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The impact of chromosomal fusions on 3D genome folding and recombination in the germ line

| Steven WashingtonSteven Washington | 0 Comment
stjosephs-hospital

The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation capture in combination with single-nucleotide polymorphism (SNP) genotyping and analysis of crossover events to study how the higher-order chromatin organization and recombination landscapes are affected by chromosomal fusions in the mammalian germ line.

 

We demonstrate that chromosomal fusions alter the nuclear architecture during meiosis, including an increased rate of heterologous interactions in primary spermatocytes, and alterations in both chromosome synapsis and axis length.

 

These disturbances in topology were associated with changes in genomic landscapes of recombination, resulting in detectable genomic footprints. Overall, we show that chromosomal fusions impact the dynamic genome topology of germ cells in two ways: (i) altering chromosomal nuclear occupancy and synapsis, and (ii) reshaping landscapes of recombination.

 

Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of HNSCC with or without HPV infection

Head and neck squamous cell carcinoma (HNSCC) are the sixth most common cancer type in the world. Human papillomavirus (HPV) infection is an emerging risk factor for HNSCC. Immune infiltration of HNSCC is linked to therapeutic results. This article aimed to decide whether variations in HPV status affect immune infiltration, molecular mechanism, and how these results vary in HNSCC patients.

 

We investigated the tumor-infiltrating immune cells (TIICs) and immune-related gene differences between HPV (+) and HPV (-) HNSCC. The gene expression quantification data of HNSCC and their clinical information were download from the TCGA database. Immune-related genes have been linked to the ImmPort platform.

 

After analyzed of 22 TIICs in the HNSCC tumor environment by CIBERSORT and further assessment, lower memory B cell and higher T cell regulatory were connected with better HPV (-) HNSCC outcome, higher activated memory CD4 T cell, higher T cell regulatory, and lower activated NK cell were linked with better HPV (+) result.

 

We finally got five forms of immune genes (CAMP, EDNRB, NTS, CXCL9, LHB) associated with HNSCC progression. Higher expressions of CAMP, EDNRB, and NTS were associated with increased overall survival in HPV (-) patients. Higher expression of CXCL9 and lower expression of LHB contributed to increased overall survival of HPV (+) patients.

 

There tend to be discrepancies in the cell structure of TIICs and immune-related genes in HPV (-) and HPV (+) HNSCC. These variances are typically too crucial for the therapeutic outcome of the patient and the development of the tumor. In specific, our sample established these candidate immune cells and immune-related genes as candidate reservoirs for further researches.

Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage

The evolutionary pressure of endemic malaria and other erythrocytic pathogens has shaped variation in genes encoding erythrocyte structural and functional proteins, influencing responses to hemolytic stress during transfusion and disease.

 

We sought to identify such genetic variants in blood donors by conducting a genome-wide association study (GWAS) of 12,353 volunteer donors, including 1,483 African Americans, 1,477 Asians, and 960 Hispanics, whose stored erythrocytes were characterized by quantitative assays of in vitro osmotic, oxidative, and cold-storage hemolysis.

GWAS revealed 27 significant loci (p<5×10-8), many in candidate genes known to modulate erythrocyte structure, metabolism, and ion channels, including SPTA1, ALDH2, ANK1, HK1, MAPKAPK5, AQP1, PIEZO1, and SLC4A1/Band 3. GWAS of oxidative hemolysis identified variants in antioxidant enzymes including GLRX, GPX4, G6PD, and a novel golgi-transport protein SEC14L4.

 

Genome wide significant loci were also tested for association with the severity of steady state (baseline) in vivo hemolytic anemia in patients with sickle cell disease, with confirmation of identified SNPs in HBA2, G6PD, PIEZO1, AQP1 and SEC14L4. Many of the identified variants, such as those in G6PD, have previously been shown to impair erythrocyte recovery after transfusion, associate with anemia, or cause rare Mendelian human hemolytic diseases.

Candidate SNPs in these genes, especially in polygenic combinations, may affect RBC recovery after transfusion and modulate disease severity in hemolytic diseases, such as sickle cell disease and malaria.

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stjosephs-hospital

Incorporating Genomic and Genetic Testing into the Treatment of Metastatic Luminal Breast Cancer

Background: Treatment of patients with luminal metastatic breast cancer (MBC) has become even more complex over the last few years as molecular profiling has begun to alter disease management. It is well accepted that MBC is not curable but is treatable. Today we are able to prolong progression-free survival and partly overall survival with targeted and more individual treatment strategies adjusted according to the molecular subtype.

Summary: Genetic and genomic testing has become therapeutically relevant in luminal MBC and is therefore an integral component within the treatment spectrum. By now, germline testing of BRCABRCAPIK3CA mutations are inevitable elements in disease management and the current state of the art in luminal MBC patients.

Furthermore, testing of ESR1 resistance mutation, ERBB2 mutation, microsatellite instability, and neurotrophic tyrosine receptor kinase (NTRK) gene fusion (mainly in secretory breast cancer) has recently gained increasing attention. However, based on the expanding role of personalized medicine, clinicians are now faced with substantial new challenges and possibly unsuspected possibilities. The following review summarizes current developments in genetic and genomic testing in luminal MBC.

Key messages: In luminal MBC genomics have become an integral component within the spectrum of oncological treatment establishing novel therapeutic facilities. Further developments in treatment personalization adjusted according to the molecular subtype should become increasingly important in order to enhance the progress of de-escalation of chemotherapy in luminal MBC. However, based on the expanding role of personalized medicine, clinicians are now faced with substantial new challenges and possibly unsuspected possibilities.

 

HIV-1 p24 ELISA Kit

Z7040001 Biochain 1 kit
EUR 974.4
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

HIV-1 p24

E5-00024 EnoGene 1mg
EUR 1152

HIV-1 p24

E62H002 EnoGene 100ug
EUR 458.4

HIV Type 1 p24 Antigen ELISA (96 Determinations)

0801111 Zeptometrix 96T
EUR 657.79
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Type 1 p24 Antigen ELISA (96 Determinations)

801111 Zeptometrix 96 Determinations
EUR 591

HIV Type 1 p24 Antigen ELISA 2.0 (96 Determinations)

0801002 Cusabio 96T
EUR 657.79
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Type 1 p24 Antigen ELISA 2.0 (96 Determinations)

801002 Zeptometrix 96 Determinations
EUR 574

HIV type 1 P24

DAG1520 Creative Diagnostics 100 µg
EUR 972

HIV-1 p24 Antibody

7313-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.

HIV-1 p24 Antibody

7313-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.

Recombinant HIV-1 p24

7-07603 CHI Scientific 100µg Ask for price

Recombinant HIV-1 p24

7-07604 CHI Scientific 500µg Ask for price

Recombinant HIV-1 p24

7-07605 CHI Scientific 1000µg Ask for price

HIV-1 Gag p24

05-005 Sceti 50 ug
EUR 434.4
Description: The HIV-1 Gag p24 is available in Europe and for worldwide shipping via Gentaur.

HIV-1 Gag p24

05-006 Sceti 250 ug
EUR 1154.4
Description: The HIV-1 Gag p24 is available in Europe and for worldwide shipping via Gentaur.

HIV-1, p24 Protein

abx069857-1mg Abbexa 1 mg
EUR 1888.8

HIV-1 p24 Protein

abx169032-1mg Abbexa 1 mg
EUR 661.2

HIV-1 p24 Antibody

20-abx137062 Abbexa
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

HIV-1 p24 Antibody

abx021869-1mg Abbexa 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021870-1mg Abbexa 1 mg
EUR 760.8

HIV-1 p24 Antibody

abx021871-1mg Abbexa 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021872-1mg Abbexa 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021873-1mg Abbexa 1 mg
EUR 794.4

HIV-1 p24 Antibody

abx021882-1mg Abbexa 1 mg
EUR 1178.4

HIV-1 p24 Antibody

abx021883-1mg Abbexa 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021886-1mg Abbexa 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021887-1mg Abbexa 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx021888-1mg Abbexa 1 mg
EUR 1220.4

HIV-1 p24 Antibody

abx023027-1ml Abbexa 1 ml
EUR 693.6

HIV 1 p24 Protein

abx060589-1mg Abbexa 1 mg
EUR 1545.6

HIV-1 p24 Protein

abx061424-05mg Abbexa 0.5 mg
EUR 886.8

HIV-1 p24 Antibody

abx023925-1mg Abbexa 1 mg
EUR 828

HIV-1 p24 Antibody

abx023926-1mg Abbexa 1 mg
EUR 828

HIV-1 p24 Protein

20-abx261886 Abbexa
  • EUR 5388.00
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

p24-HIV(p24/661) Antibody

BNCA0661-250 Biotium 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), APC conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCAP0661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCAP0661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC610661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF660R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC610661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF660R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCR0661-250 Biotium 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), RPE conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNUB0661-100 Biotium 100uL
EUR 250.8
Description: Primary antibody against p24-HIV(p24/661), Concentration: 0.2mg/mL

p24-HIV(p24/661) Antibody

BNUB0661-500 Biotium 500uL
EUR 549.6
Description: Primary antibody against p24-HIV(p24/661), Concentration: 0.2mg/mL

p24-HIV(p24/661) Antibody

BNC430661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF543 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC430661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF543 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC400661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF640R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC400661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF640R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC880661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF488A conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC880661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF488A conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC810661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF680R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC810661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF680R conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCH0661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCH0661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCP0661-250 Biotium 250uL
EUR 459.6
Description: Primary antibody against p24-HIV(p24/661), PerCP conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNUM0661-50 Biotium 50uL
EUR 474
Description: Primary antibody against p24-HIV(p24/661), 1mg/mL

p24-HIV(p24/661) Antibody

BNC050661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF405M conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC050661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF405M conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC680661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF568 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC680661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF568 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC700661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF770 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC700661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF770 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC800661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF680 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC800661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF680 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCB0661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), Biotin conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNCB0661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), Biotin conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC940661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF594 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC940661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF594 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC550661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF555 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC550661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF555 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC470661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF647 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC470661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF647 conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC040661-100 Biotium 100uL
EUR 238.8
Description: Primary antibody against p24-HIV(p24/661), CF405S conjugate, Concentration: 0.1mg/mL

p24-HIV(p24/661) Antibody

BNC040661-500 Biotium 500uL
EUR 652.8
Description: Primary antibody against p24-HIV(p24/661), CF405S conjugate, Concentration: 0.1mg/mL

HIV p24 Antibody

abx021867-1mg Abbexa 1 mg
EUR 1612.8

HIV p24 Antibody

abx021868-1mg Abbexa 1 mg
EUR 1612.8

Human(HIV-P24)

QY-E05679 Qayee Biotechnology 96T
EUR 433.2

HIV Type 1 p24 Antigen ELISA (5 X 96 Determinations)

801200 Zeptometrix 5 X 96 Determinations
EUR 2330

HIV Type 1 p24 Antigen ELISA (5 X 96 Determinations)

0801200 Zeptometrix 5 X 96T
EUR 2543.52
Description: Please contact Gentaur in order to receive the datasheet of the product.

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 Alpha Diagnostics 1
EUR 242.4

HIV type 1 P24 [His]

DAG2375 Creative Diagnostics 100 µg
EUR 868.8

HIV type 1 P24 [His]

DAG2377 Creative Diagnostics 100 µg
EUR 868.8

HIV type 1 p24 [FITC]

DAGH004 Creative Diagnostics 50 Tests
EUR 1112.4

HIV type 1 P24 [GST]

DAG1516 Creative Diagnostics 100 µg
EUR 774

HIV type 1 P24 [His]

DAG1518 Creative Diagnostics 100 µg
EUR 774

HIV type 1 P24 [Biotin]

DAG1519 Creative Diagnostics 100 µg
EUR 972

HIV type 1 P24 [His]

DAG1799 Creative Diagnostics 50 ug
EUR 2017.2

HIV-1 p24 Recombinant Protein

53-341 ProSci 0.01 mg
EUR 789.9
Description: HIV-1 p24 Recombinant Protein

Recombinant HIV-1 p24 Core

7-07597 CHI Scientific 100µg Ask for price

Recombinant HIV-1 p24 Core

7-07598 CHI Scientific 500µg Ask for price

Recombinant HIV-1 p24 Core

7-07599 CHI Scientific 1000µg Ask for price

Recombinant HIV-1 p24 , 24kDa

7-07621 CHI Scientific 2µg Ask for price

Recombinant HIV-1 p24 , 24kDa

7-07622 CHI Scientific 10µg Ask for price

Recombinant HIV-1 p24 , 24kDa

7-07623 CHI Scientific 100µg Ask for price

HIV 1 / 2 p24 Antibody

abx021866-1mg Abbexa 1 mg
EUR 1212

HIV-1 p24 Antibody (FITC)

abx021884-100ug Abbexa 100 ug
EUR 886.8

HIV 1 / 2 p24 Antibody

abx021890-1mg Abbexa 1 mg
EUR 1212

HIV-1 p24 Antibody (FITC)

abx023026-1ml Abbexa 1 ml
EUR 678

HIV-1 p24 Antibody (Biotin)

abx023028-1ml Abbexa 1 ml
EUR 794.4

HIV-1 p24 Antibody (HRP)

abx023029-1ml Abbexa 1 ml
EUR 886.8

HIV-1 p24 Core Protein

20-abx260141 Abbexa
  • EUR 1062.00
  • EUR 410.40
  • EUR 1646.40
  • 0.5 mg
  • 100 ug
  • 1 mg

Polyclonal HIV-1 p24 Antibody

APR11116G Leading Biology 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIV-1 p24 . This antibody is tested and proven to work in the following applications:

HIV-1 p24, His tag

E410A26-20 EnoGene 20μg
EUR 520.8

HIV-1 p24 Antibody [8G9]

PM-6335-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9]

PM-6335-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4]

PM-6585-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4]

PM-6585-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

Anti-HIV-1 p24 Antibody

STJ60071 St John's Laboratory 100 µg
EUR 508.8

Anti-HIV-1 p24 Antibody

STJ60072 St John's Laboratory 100 µg
EUR 508.8

HIV Type-1 p24 Antibody

V2344-100UG NSJ Bioreagents 100 ug
EUR 499
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

HIV Type-1 p24 Antibody

V2344-20UG NSJ Bioreagents 20 ug
EUR 219
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

HIV Type-1 p24 Antibody

V2344CF488-100T NSJ Bioreagents 100 Tests
EUR 499
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

HIV Type-1 p24 Antibody

V2344SAF-100UG NSJ Bioreagents 100 ug
EUR 499
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Human HIV(1+2 antibodies plus p24 antigen (4th Generation) ELISA Kit

EH4101 FN Test 96T
EUR 571.5
Description: Method of detection: Qualitative ;Reacts with: Homo sapiens;Sensitivity: Qualitative

HIV Type 1 p24 Antigen ELISA 2.0 (5 X 96 Determinations)

0801008 Zeptometrix 5 X 96T
EUR 2543.52
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Type 1 p24 Antigen ELISA 2.0 (5 X 96 Determinations)

801008 Zeptometrix 5 X 96 Determinations
EUR 2386

HIV-1 p24 Immune Complex Dissociation Kit

Z7040009 Biochain 1 kit
EUR 207.6
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Anti-HIV p24 antibody

10-2842 Fitzgerald 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

Anti-HIV p24 antibody

10-2843 Fitzgerald 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

Anti-HIV p24 antibody

10-2844 Fitzgerald 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

Anti-HIV p24 antibody

10-2845 Fitzgerald 1 mg
EUR 360
Description: Anti-HIV p24 Ag monoclonal antibody

QuickTiter HIV Lentivirus Quantitation Kit (p24 ELISA)

VPK-108-H Cell Biolabs 96 assays
EUR 866.4
Description: Quantitation of the HIV-1 p24 core protein of a lentiviral vector is an efficient, well-published method for determining lentivirus physical titer. The QuickTiter Lentivirus Quantitation Kits provide a convenient method of p24 antigen quantitation.

QuickTiter HIV Lentivirus Quantitation Kit (p24 ELISA)

VPK-108-H-5 Cell Biolabs 5 x 96 assays
EUR 3560.4
Description: Quantitation of the HIV-1 p24 core protein of a lentiviral vector is an efficient, well-published method for determining lentivirus physical titer. The QuickTiter Lentivirus Quantitation Kits provide a convenient method of p24 antigen quantitation.

HIV type 1 P24 (HXBc2) [His]

DAG2376 Creative Diagnostics 100 µg
EUR 868.8

HIV type 1 P24 (p24HXBc2) [His]

DAG2378 Creative Diagnostics 100 µg
EUR 1095.6

HIV type 1 P24 (CN54) [His]

DAG2380 Creative Diagnostics 100 µg
EUR 1095.6

Recombinant HIV-1 p24 Core, Sf9

7-07600 CHI Scientific 2µg Ask for price

Recombinant HIV-1 p24 Core, Sf9

7-07601 CHI Scientific 10µg Ask for price

Recombinant HIV-1 p24 Core, Sf9

7-07602 CHI Scientific 100µg Ask for price

Recombinant HIV-1 p24 His Tag

7-07606 CHI Scientific 5µg Ask for price

Recombinant HIV-1 p24 His Tag

7-07607 CHI Scientific 20µg Ask for price

Recombinant HIV-1 p24 His Tag

7-07608 CHI Scientific 1mg Ask for price

Recombinant HIV-1 p24, Biotin Labeled

7-07612 CHI Scientific 100µg Ask for price

Recombinant HIV-1 p24, Biotin Labeled

7-07613 CHI Scientific 500µg Ask for price

Recombinant HIV-1 p24, Biotin Labeled

7-07614 CHI Scientific 1000µg Ask for price

Recombinant HIV-1 gag p17, p24

7-07675 CHI Scientific 100µg Ask for price

Recombinant HIV-1 gag p17, p24

7-07676 CHI Scientific 500µg Ask for price

Recombinant HIV-1 gag p17, p24

7-07677 CHI Scientific 1000µg Ask for price

Mouse antibody for HIV-1 p24

1941 Virostat 100 ug
EUR 399.3
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1946 Virostat 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1947 Virostat 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1948 Virostat 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

Mouse antibody for HIV-1 p24

1949 Virostat 100 ug
EUR 425.4
Description: This is purified Mouse monoclonal antibody against HIV-1 p24 for WB, ELISA.

HIV-1 gag p24 IIIB Protein

abx060586-05mg Abbexa 0.5 mg
EUR 1128

HIV-1 p24 Core, Sf9 Protein

20-abx260012 Abbexa
  • EUR 2815.20
  • EUR 493.20
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

HIV-1 gag p17, p24 Protein

20-abx260277 Abbexa
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 p24, Biotin Labeled Protein

20-abx260358 Abbexa
  • EUR 1496.40
  • EUR 560.40
  • EUR 2364.00
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 p24, 24 kDa Protein

20-abx263118 Abbexa
  • EUR 1562.40
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Polyclonal HIV-1 p24 Antibody [7F4]

APR11117G Leading Biology 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Mouse that recognizes and binds to Human HIV-1 p24 [7F4] . This antibody is tested and proven to work in the following applications:

HIV-1 p24 Antibody [8G9] (biotin)

PM-6335-biotin-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9] (biotin)

PM-6335-biotin-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9] (HRP)

PM-6335-HRP-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [8G9] (HRP)

PM-6335-HRP-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (biotin)

PM-6585-biotin-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (biotin)

PM-6585-biotin-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (HRP)

PM-6585-HRP-002mg ProSci 0.02 mg
EUR 206.18
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

HIV-1 p24 Antibody [7F4] (HRP)

PM-6585-HRP-01mg ProSci 0.1 mg
EUR 523.7
Description: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

Recombinant HIV-1 p24 Protein [His]

VAng-0527Lsx-inquire Creative Biolabs inquire Ask for price
Description: HIV type 1 P24 Antigen, recombinant protein from insect cell expression system.

Recombinant HIV-1 P24 Protein (Gorillas)

VAng-Lsx0245-1mg Creative Biolabs 1 mg
EUR 3058.8
Description: HIV type 1 P24 (Antigen), recombinant protein from E. coli.

Monoclonal Mouse Anti-Hiv(P24)

C010105-10mg Unibiotest 10mg
EUR 1641.6

Monoclonal Mouse Anti-Hiv(P24)

C010105-1mg Unibiotest 1mg
EUR 322.8

Recombinant HIV-I p24 gag

7-07618 CHI Scientific 100µg Ask for price

Recombinant HIV-I p24 gag

7-07619 CHI Scientific 500µg Ask for price

Recombinant HIV-I p24 gag

7-07620 CHI Scientific 1000µg Ask for price

anti-HIV p24 Monoclonal antibody

012-A-01mg Virogen 0,1 mg
EUR 321
Description: anti-HIV-1 p24 IgG1 (monoclonal) Produced against a recombinant protein.

anti-HIV p24 Monoclonal antibody

012-A-1000ug Virogen 1000 ug
EUR 1539
Description: anti-HIV-1 p24 IgG1 (monoclonal) Produced against a recombinant protein.

HIV-I p24 gag Protein

20-abx260279 Abbexa
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

Anti-HIV p24 protein antibody

STJ16100518 St John's Laboratory 100 µg
EUR 487.2

Anti-HIV/p24 monoclonal Antibody

A1020-100 Biovision each
EUR 444

Goat Anti-HIV-1 p24 Polyclonal Antibody

DPAB0249 Creative Diagnostics 1 ml
EUR 781.2

Goat Anti-HIV-1 p24 Polyclonal Antibody

DPAB0250 Creative Diagnostics 1 ml
EUR 826.8

Goat Anti-HIV-1 p24 Polyclonal Antibody

DPAB0251 Creative Diagnostics 1 ml
EUR 1146

HIV-1 gag Protein p24 (137-154)

5-01316 CHI Scientific 4 x 1mg Ask for price

HIV-1 gag Protein p24 (194-210)

5-01317 CHI Scientific 4 x 1mg Ask for price

Recombinant HIV-1 p24 gag, His Tag

7-07609 CHI Scientific 100µg Ask for price

Recombinant HIV-1 p24 gag, His Tag

7-07610 CHI Scientific 500µg Ask for price

Recombinant HIV-1 p24 gag, His Tag

7-07611 CHI Scientific 1000µg Ask for price

Recombinant HIV-1 p24, Horseradish Peroxidase Labeled

7-07615 CHI Scientific 100µg Ask for price

Recombinant HIV-1 p24, Horseradish Peroxidase Labeled

7-07616 CHI Scientific 500µg Ask for price

Recombinant HIV-1 p24, Horseradish Peroxidase Labeled

7-07617 CHI Scientific 1000µg Ask for price

Recombinant HIV-1 gag p17, p24, gp120

7-07678 CHI Scientific 100µg Ask for price

Recombinant HIV-1 gag p17, p24, gp120

7-07679 CHI Scientific 500µg Ask for price

Recombinant HIV-1 gag p17, p24, gp120

7-07680 CHI Scientific 1000µg Ask for price

Anti-Capsid protein p24 (HIV-1) Purified

11-327-C025 ExBio 0.025 mg
EUR 135.6

Anti-Capsid protein p24 (HIV-1) Purified

11-327-C100 ExBio 0.1 mg
EUR 223.2

Mouse Monoclonal Anti- HIV-1 p24 IgG

AB-15210 Alpha Diagnostics 100 ug
EUR 416.4

HIV-1 gag p17, p24, gp120 Protein

20-abx260274 Abbexa
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 p24, Horseradish Peroxidase Labeled Protein

20-abx260359 Abbexa
  • EUR 1496.40
  • EUR 560.40
  • EUR 2364.00
  • 0.5 mg
  • 100 ug
  • 1 mg

HIV-1 gag Protein p24 (194-210)

H-2986.0500 Bachem 0.5mg
EUR 327.6
Description: Sum Formula: C73H126N20O23S; CAS# [141281-67-6]

HIV-1 gag Protein p24 (194-210)

H-2986.1000 Bachem 1.0mg
EUR 559.2
Description: Sum Formula: C73H126N20O23S; CAS# [141281-67-6]

HIV-1 gag Protein p24 (137-154)

H-3006.0500 Bachem 0.5mg
EUR 327.6
Description: Sum Formula: C92H158N26O26S; CAS# [198636-98-5]

HIV-1 gag Protein p24 (137-154)

H-3006.1000 Bachem 1.0mg
EUR 559.2
Description: Sum Formula: C92H158N26O26S; CAS# [198636-98-5]
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