cusabio specializes in the production of antibody

Recombinant Antibody Production

Reference

CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit. Our products have been widely used by researchers in the worldwide. Now, we have listed a part of the publications citing our products, you can enter the catalog number to search the products what you want and see the corresponding reference.

Custom Recombinant Antibody Production

Recombinant antibody, also known as genetic engineering antibody, refers to the usage of recombinant DNA and protein engineering technology to modify or recombine antibody genes according to various needs, then expressed after transfection via appropriate receptor cell.
Cusabio could offer one-stop service of recombinant antibody production to customers upon your various needs.
The production process of Cusabio custom recombinant antibody is as follows.

cusabio specializes in the production of antibody

cusabio specializes in the production of antibody

Process & Deliverables:

Antigen Preparation Process Deliverables Production Time
Peptide Synthesis
  • Select Positive Gene
  • Recombinant Antibody Expression
  • Protein A/G Purification
  • ELISA, WB Validation
  1. QC report of antigen;
  2. 100ug×purified recombinant antibodies together with QC report, including the information of gene sequencing, concentration, purity and endotoxin content;
  3. WB positive guarantee for antigen;
  4. Other applications(IHC, IF, IP, FC, ChIP) could be available upon customers’ requests.
8-16 weeks
Recombinant Protein Production 12-16 weeks
Native Protein Selection 12-16 weeks

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the small lymphocyte subtype. Mature B cells mainly reside in the lymph nodes in the superficial layer of the lymph node cortex and in the red and white nodes of the spleen. B cells can differentiate into plasma cells under the stimulation of antigens. Plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity of the body. In this article, we collect several question about B cell, and want to these information help you understand this kind of cell.

What is The Function of B Cell?

The function of B cell mainly includes two sections. On the one hand, they function in the humoral immunity component of the adaptive immune system by secreting antibodies. These antibodies serve as flags or the flares over a battle site. They recruit other defensive molecules in the bloodstream to the site, working toward killing the infection-causing organism. They also signal other immune cells to, in turn, wage war on the invader.

In addition to their essential role in humoral immunity, B cells also regulate many other functions essential for immune homeostasis. Of major importance, B cells are required for the initiation of T-cell immune responses by B cells antigen presenting and cytokines secreting.

In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, and not from bone marrow as commonly believed.

What is The B Cell Differentiation?

The differentiation process of mammalian B cells can be divided into five stages: pre-B cells, immature B cells, mature B cells, activated B cells, and plasma cells. Among them, the differentiation of pre-B cells and immature B cells is antigen-untrusted, and the differentiation process is performed in the bone marrow. The antigen-dependent phase refers to mature B cells that are activated after antigen stimulation and continue to differentiate into plasma cells that synthesize and secrete antibodies. This stage of differentiation is mainly performed in peripheral immune organs.

Some of the activated B-cells become memory B-cells, which have very long lives in the bone marrow, lymph nodes and spleen. They remember the antigen they are specific for and are ready to respond quickly if they see it again. These are the cells that give us long-lasting immunity to different invaders. (Figure 1).

 

MEK5 recombinant monoclonal antibody

A5672 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human MEK5 for WB, IF,ELISA

MEK7 recombinant monoclonal antibody

A5673 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human MEK7 for WB, IF,ELISA

HDAC10 recombinant monoclonal antibody

A5674 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human HDAC10 for WB, IF,ELISA

FOXO4 recombinant monoclonal antibody

A5675 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human FOXO4 for WB ,ELISA

JNK3 recombinant monoclonal antibody

A5677 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human JNK3 for WB, IF,ELISA

PAX7 recombinant monoclonal antibody

A5679 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PAX7 for WB ,ELISA

Cdc25B recombinant monoclonal antibody

A5684 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Cdc25B for WB ,ELISA

CDC45 recombinant monoclonal antibody

A5685 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CDC45 for WB ,ELISA

CDC40 recombinant monoclonal antibody

A5686 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CDC40 for WB ,ELISA

HSPA4 recombinant monoclonal antibody

A5688 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human HSPA4 for WB ,ELISA

CDC42 recombinant monoclonal antibody

A5689 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CDC42 for WB, IHC,ELISA

CITED2 recombinant monoclonal antibody

A5692 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CITED2 for WB ,ELISA

E2F1 recombinant monoclonal antibody

A5693 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human E2F1 for WB, IHC, IF,ELISA

Bmi1 recombinant monoclonal antibody

A5694 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Bmi1 for WB, IF,ELISA

PTP1B recombinant monoclonal antibody

A5695 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PTP1B for WB ,ELISA

PDIA6 recombinant monoclonal antibody

A5698 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PDIA6 for WB, IF,ELISA

RAGE recombinant monoclonal antibody

A5699 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human RAGE for WB ,ELISA

Dnmt1 recombinant monoclonal antibody

A5700 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Dnmt1 for WB, IF,ELISA

ABCG2 recombinant monoclonal antibody

A5702 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ABCG2 for WB ,ELISA

PDHA1 recombinant monoclonal antibody

A5703 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PDHA1 for WB, IF,ELISA

ASPP2 recombinant monoclonal antibody

A5704 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ASPP2 for WB, IF,ELISA

CD19 recombinant monoclonal antibody

A5705 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CD19 for WB ,ELISA

SERPINA1 recombinant monoclonal antibody

A5706 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human SERPINA1 for WB, IHC,ELISA

SERCA2 recombinant monoclonal antibody

A5708 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human SERCA2 for WB, IHC, IF,ELISA

FGFR2 recombinant monoclonal antibody

A5709 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human FGFR2 for WB ,ELISA

FGF21 recombinant monoclonal antibody

A5710 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human FGF21 for WB ,ELISA

KIFC1 recombinant monoclonal antibody

A5713 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human KIFC1 for WB, IHC, IF,ELISA

RNF20 recombinant monoclonal antibody

A5714 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human RNF20 for WB,ELISA

Smad3 recombinant monoclonal antibody

A5715 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Smad3 for WB, IHC,ELISA

CDK2 recombinant monoclonal antibody

A5716 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CDK2 for WB,ELISA

CCR9 recombinant monoclonal antibody

A5717 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CCR9 for WB,ELISA

Survivin recombinant monoclonal antibody

A5719 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Survivin for WB,ELISA

CDX2 recombinant monoclonal antibody

A5720 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CDX2 for WB, IHC,ELISA

p53 recombinant monoclonal antibody

A5722 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human p53 for WB,ELISA

HDAC1 recombinant monoclonal antibody

A5723 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human HDAC1 for WB, IF,ELISA

TRAF6 recombinant monoclonal antibody

A5724 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human TRAF6 for WB, IHC,ELISA

MMP9 recombinant monoclonal antibody

A5725 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human MMP9 for WB,ELISA