cusabio specializes in the production of antibody

Recombinant Antibody Production

Reference

CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit. Our products have been widely used by researchers in the worldwide. Now, we have listed a part of the publications citing our products, you can enter the catalog number to search the products what you want and see the corresponding reference.

Custom Recombinant Antibody Production

Recombinant antibody, also known as genetic engineering antibody, refers to the usage of recombinant DNA and protein engineering technology to modify or recombine antibody genes according to various needs, then expressed after transfection via appropriate receptor cell.
Cusabio could offer one-stop service of recombinant antibody production to customers upon your various needs.
The production process of Cusabio custom recombinant antibody is as follows.

cusabio specializes in the production of antibody

cusabio specializes in the production of antibody

Process & Deliverables:

Antigen Preparation Process Deliverables Production Time
Peptide Synthesis
  • Select Positive Gene
  • Recombinant Antibody Expression
  • Protein A/G Purification
  • ELISA, WB Validation
  1. QC report of antigen;
  2. 100ugĂ—purified recombinant antibodies together with QC report, including the information of gene sequencing, concentration, purity and endotoxin content;
  3. WB positive guarantee for antigen;
  4. Other applications(IHC, IF, IP, FC, ChIP) could be available upon customers’ requests.
8-16 weeks
Recombinant Protein Production 12-16 weeks
Native Protein Selection 12-16 weeks

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the small lymphocyte subtype. Mature B cells mainly reside in the lymph nodes in the superficial layer of the lymph node cortex and in the red and white nodes of the spleen. B cells can differentiate into plasma cells under the stimulation of antigens. Plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity of the body. In this article, we collect several question about B cell, and want to these information help you understand this kind of cell.

What is The Function of B Cell?

The function of B cell mainly includes two sections. On the one hand, they function in the humoral immunity component of the adaptive immune system by secreting antibodies. These antibodies serve as flags or the flares over a battle site. They recruit other defensive molecules in the bloodstream to the site, working toward killing the infection-causing organism. They also signal other immune cells to, in turn, wage war on the invader.

In addition to their essential role in humoral immunity, B cells also regulate many other functions essential for immune homeostasis. Of major importance, B cells are required for the initiation of T-cell immune responses by B cells antigen presenting and cytokines secreting.

In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, and not from bone marrow as commonly believed.

What is The B Cell Differentiation?

The differentiation process of mammalian B cells can be divided into five stages: pre-B cells, immature B cells, mature B cells, activated B cells, and plasma cells. Among them, the differentiation of pre-B cells and immature B cells is antigen-untrusted, and the differentiation process is performed in the bone marrow. The antigen-dependent phase refers to mature B cells that are activated after antigen stimulation and continue to differentiate into plasma cells that synthesize and secrete antibodies. This stage of differentiation is mainly performed in peripheral immune organs.

Some of the activated B-cells become memory B-cells, which have very long lives in the bone marrow, lymph nodes and spleen. They remember the antigen they are specific for and are ready to respond quickly if they see it again. These are the cells that give us long-lasting immunity to different invaders. (Figure 1).

 

Mouse Recombinant anti-Human CD8 Recombinant Antibody

xAP-0344 100ug
EUR 280

Mouse Recombinant anti-Human LAP Recombinant Antibody

xAP-0443 100ug
EUR 280

Rat Recombinant anti-Mouse CD11c Recombinant Antibody

xAP-0518 100ug
EUR 280

Rat Recombinant anti-Mouse CD154 Recombinant Antibody

xAP-0545 100ug
EUR 280

Rat Recombinant anti-Mouse CD62L Recombinant Antibody

xAP-0679 100ug
EUR 280

Mouse Recombinant anti-Rat CD161 Recombinant Antibody

xAP-0871 100ug
EUR 280

Mouse Recombinant anti-Human CD10 Recombinant Antibody

xAP-0047 100ug
EUR 280

Mouse Recombinant anti-Human CD14 Recombinant Antibody

xAP-0102 100ug
EUR 280

Mouse Recombinant anti-Human CD14 Recombinant Antibody

xAP-0103 100ug
EUR 280

Mouse Recombinant anti-Human CD14 Recombinant Antibody

xAP-0104 100ug
EUR 280

Mouse Recombinant anti-Human CD15 Recombinant Antibody

xAP-0118 100ug
EUR 280

Mouse Recombinant anti-Human CD16 Recombinant Antibody

xAP-0129 100ug
EUR 280

Mouse Recombinant anti-Human CD25 Recombinant Antibody

xAP-0197 100ug
EUR 280

Mouse Recombinant anti-Human CD27 Recombinant Antibody

xAP-0204 100ug
EUR 280

Mouse Recombinant anti-Human CD38 Recombinant Antibody

xAP-0258 100ug
EUR 280

Mouse Recombinant anti-Human CD38 Recombinant Antibody

xAP-0259 100ug
EUR 280

Mouse Recombinant anti-Human CD40 Recombinant Antibody

xAP-0269 100ug
EUR 280

Mouse Recombinant anti-Human CD45 Recombinant Antibody

xAP-0280 100ug
EUR 280

Mouse Recombinant anti-Human CD45 Recombinant Antibody

xAP-0281 100ug
EUR 280

Mouse Recombinant anti-Human CD52 Recombinant Antibody

xAP-0300 100ug
EUR 280

Mouse Recombinant anti-Human CD53 Recombinant Antibody

xAP-0301 100ug
EUR 280

Mouse Recombinant anti-Human CD57 Recombinant Antibody

xAP-0311 100ug
EUR 280

Mouse Recombinant anti-Human CD59 Recombinant Antibody

xAP-0314 100ug
EUR 280

Mouse Recombinant anti-Human CD80 Recombinant Antibody

xAP-0347 100ug
EUR 280

Mouse Recombinant anti-Human CD8a Recombinant Antibody

xAP-0360 100ug
EUR 280

Mouse Recombinant anti-Human CD8b Recombinant Antibody

xAP-0361 100ug
EUR 280

Mouse Recombinant anti-Mouse CD19 Recombinant Antibody

xAP-0562 100ug
EUR 280

Mouse Recombinant anti-Mouse CD20 Recombinant Antibody

xAP-0570 100ug
EUR 280

Mouse Recombinant anti-Mouse CD3e Recombinant Antibody

xAP-0641 100ug
EUR 280

Mouse Recombinant anti-Mouse CD45 Recombinant Antibody

xAP-0657 100ug
EUR 280

Mouse Recombinant anti-Mouse CD48 Recombinant Antibody

xAP-0666 100ug
EUR 280

Mouse Recombinant anti-Mouse CD8a Recombinant Antibody

xAP-0705 100ug
EUR 280

Mouse Recombinant anti-Human CD11b Recombinant Antibody

xAP-0072 100ug
EUR 280

Mouse Recombinant anti-Human CD123 Recombinant Antibody

xAP-0081 100ug
EUR 280

Mouse Recombinant anti-Human CD161 Recombinant Antibody

xAP-0132 100ug
EUR 280

Mouse Recombinant anti-Human CD163 Recombinant Antibody

xAP-0136 100ug
EUR 280

Mouse Recombinant anti-Human CD305 Recombinant Antibody

xAP-0225 100ug
EUR 280