Mycobacterium tuberculosis (Mtb) strains of Beijing lineage have brought about nice concern due to their speedy emergence of drug resistance and worldwide unfold. DNA mutation charges that mirror evolutional adaptation
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A compound heterozygous mutation of the alkaline phosphatase ALPL gene causes hypophosphatasia in a Han Chinese familyA compound heterozygous mutation of the alkaline phosphatase ALPL gene causes hypophosphatasia in a Han Chinese family
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Hypophosphatasia (HPP) is a uncommon hereditary systemic illness that’s characterised by faulty bone and/or dental mineralization, and is brought on by mutations within the alkaline phosphatase gene (ALPL). The current
The impact of chromosomal fusions on 3D genome folding and recombination in the germ lineThe impact of chromosomal fusions on 3D genome folding and recombination in the germ line
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The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of
The development and controversy of competitive endogenous RNA hypothesis in non-coding genesThe development and controversy of competitive endogenous RNA hypothesis in non-coding genes
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As a momentous post-transcriptional regulator, microRNAs (miRNAs) are attracting more and more attention. The classical miRNAs regulated mechanism shows it binds to the targets’ 3’UTR thus play the role in