ePath: an online database towards comprehensive essential gene annotation for prokaryotes.

Experimental techniques for identifying essential genes (for example) in prokaryotes are generally expensive, taking a long time and sometimes unrealistic. Emerging silico methods provide alternative methods for for example prediction, but often have limits including significant calculation requirements and a lack...

A Simple Method for Sample Preparation to Facilitate Efficient Whole-Genome Sequencing of African Swine Fever Virus.

In recent years, African swine fever has become the main threat of animal health for the pig industry. To facilitate the rapid genetic analysis of its causal agent, the African swine fever virus (ASFV), we have developed a simple and effective...

Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics.

Despite hundreds of sequentered arabidopsis genomes, very few things are known about the degree of genomic collinearity within a single species due to the low number of assemblies at the chromosome level. Here we report assemblies of reference quality at the...

MIST: A multiloci identification system for Trichoderma

Due to the rapid expansion of microbial taxonomy, an accurate identification of common mushrooms in industry and agriculture such as trichoderma species are difficult. In this study, we introduce the online multi-line identification system (fog) for automated three hundred and forty-nine...

Development and Application of a Prophage Integrase Typing Scheme for Group B Streptococcus

Group B Streptococcus (GBS) is a gram-positive pathogen that mainly affects humans, livestock and fish. Mobile genetic elements play an important role in the evolution of GBS, its adaptation to species and host niches, as well as its pathogenicity. In particular,...

Molecular docking and Pharmacoinformatics studies reveal potential phytochemicals against HCV NS5B Polymerase

The Hepatitis C (HCV) virus is one of the serious health problems affecting a third of the world’s population. The high variations of the HCV genome are assigned to rapid replication by NS5B polymerase and therefore constitute the most attractive target...