Background: Mechanisms driving the progression of chronic lymphocytic leukemia (CLL) from its early stages are not fully understood. The acquisition of molecular changes at the time of progression has been observed in a small fraction of patients, suggesting that CLL progression is not mainly driven by dynamic clonal evolution. In order to shed light on mechanisms that lead to CLL progression, we investigated longitudinal changes in both the genetic and immunological scenarios.
Methods: We performed genetic and immunological longitudinal analysis using paired primary samples from untreated CLL patients that underwent clinical progression (sampling at diagnosis and progression) and from patients with stable disease (sampling at diagnosis and at long-term asymptomatic follow-up).
Results: Molecular analysis showed limited and non-recurrent molecular changes at progression, indicating that clonal evolution is not the main driver of clinical progression. Our analysis of the immune kinetics found an increasingly dysfunctional CD8+ T cell compartment in progressing patients that was not observed in those patients that remained asymptomatic.
Specifically, terminally exhausted effector CD8+ T cells (T-betdim/-EomeshiPD1hi) accumulated, while the the co-expression of inhibitory receptors (PD1, CD244 and CD160) increased, along with an altered gene expression profile in T cells only in those patients that progressed. In addition, malignant cells from patients at clinical progression showed enhanced capacity to induce exhaustion-related markers in CD8+ T cells ex vivo mainly through a mechanism dependent on soluble factors including IL-10.
Conclusions: Altogether, we demonstrate that the interaction with the immune microenvironment plays a key role in clinical progression in CLL, thereby providing a rationale for the use of early immunotherapeutic intervention.
Searching for signatures of positive selection in cytochrome b gene associated with subterranean lifestyle in fast-evolving arvicolines (Arvicolinae, Cricetidae, Rodentia)
Background: Mitochondrial genes encode proteins involved in oxidative phosphorylation. Variations in lifestyle and ecological niche can be directly reflected in metabolic performance. Subterranean rodents represent a good model for testing hypotheses on adaptive evolution driven by important ecological shifts.
Voles and lemmings of the subfamily Arvicolinae (Rodentia: Cricetidae) provide a good example for studies of adaptive radiation. This is the youngest group within the order Rodentia showing the fastest rates of diversification, including the transition to the subterranean lifestyle in several phylogenetically independent lineages.
Results: We evaluated the signatures of selection in the mitochondrial cytochrome b (cytB) gene in 62 Arvicolinae species characterized by either subterranean or surface-dwelling lifestyle by assessing amino acid sequence variation, exploring the functional consequences of the observed variation in the tertiary protein structure, and estimating selection pressure. Our analysis revealed that:
(1) three of the convergent amino acid substitutions were found among phylogenetically distant subterranean species and
(2) these substitutions may have an influence on the protein complex structure
(3) cytB showed an increased ω and evidence of relaxed selection in subterranean lineages, relative to non-subterranean, and
(4) eight protein domains possess increased nonsynonymous substitutions ratio in subterranean species.
Conclusions: Our study provides insights into the adaptive evolution of the cytochrome b gene in the Arvicolinae subfamily and its potential implications in the molecular mechanism of adaptation. We present a framework for future characterizations of the impact of specific mutations on the function, physiology, and interactions of the mtDNA-encoded proteins involved in oxidative phosphorylation.
stjosephs-hospital
Screening of wheat genotypes for the presence of common bunt resistance genes
Common bunt is known to cause grain yield and quality losses in wheat due to bunt ball formation and infestation of the grain. The aim of this study is to identify for sources of resistance to common bunt in wheat genotypes using phytopathological and molecular methods. In general, studied 60 Kazakh and foreign wheat genotypes were found 15 samples with the Bt9, Bt8 and Bt11 genes. Carriers of the Bt10 gene include the five varieties.
The four resistance genes, Bt8, Bt10, Bt11, Bt9, and Bt10 were identified in the Karasai variety. Phytopathological and molecular screening of Kazakh and foreign wheat genotypes selected 18 with genes for resistance to the disease. According to evaluation on an artificial infection 19 varieties showed an immune type of reaction.
These varieties will be used in breeding programs as donors to create resistant varieties against the common bunt. Thus, approaches can reduce the level of fungicides use and the most effective method to control the common bunt.
Genetic Mutations Associated with Pierre Robin Syndrome/Sequence: A Systematic Review
Pierre Robin syndrome/sequence (PRS) is associated with a triad of symptoms that includes micrognathia, cleft palate, and glossoptosis that may lead to respiratory obstruction. The syndrome occurs in 2 forms: nonsyndromic PRS (nsPRS), and PRS associated with other syndromes (sPRS). Studies have shown varying genetic mutations associated with both nsPRS and sPRS.
The present systematic review aims to provide a comprehensive collection of published literature reporting genetic mutations in PRS. Web of Science, PubMed, and Scopus were searched using the keywords: “Pierre Robin syndrome/sequence AND gene mutation.”
- The search resulted in 208 articles, of which 93 were excluded as they were duplicates/irrelevant.
- The full-text assessment led to the further exclusion of 76 articles. From the remaining 39 articles included in the review, details of 324 cases were extracted. 56% of the cases were sPRS, and 22% of the cases were associated with other malformations and the remaining were nsPRS.
- Genetic mutations were noted in 30.9% of the 300 cases. Based on the review, SOX9 was found to be the most common gene associated with both nsPRS and sPRS. The gene mutation in sPRS was specific to the associated syndrome.
- Due to the lack of original studies, a quantitative analysis was not possible. Thus, future studies must focus on conducting large-scale cohort studies.
- Along with generating data on genetic mutation, future studies must also conduct pedigree analysis to assess potential familial inheritance, which in turn could provide valuable insights into the etiopathogenesis of PRS.
 HTLV-I Envelope Recombinant Antigen |
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| 00203-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HLTV-I envelope recombinant antigen. C-terminus of gp-46 and most of p21. |
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HTLV-I Envelope Recombinant Antigen |
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| 00203-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HLTV-I envelope recombinant antigen. C-terminus of gp-46 and most of p21. |
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) Anti-HTLV Type I p19 Clone TP-7 (100 µg) |
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| 0801003 | Zeptometrix | 100 µg | EUR 340.8 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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) Anti-HTLV Type I p19 Clone 45/6.11.1.3 (100 µg) |
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| 0801082 | Zeptometrix | 100 µg | EUR 340.8 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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) Anti-HTLV Type II p19 Clone 78/6.18.07 (100 µg) |
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| 0801093 | Zeptometrix | 100 µg | EUR 340.8 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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) Anti-HTLV Type I p19 Clone TP-7 (1 mg) |
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| 0801107 | Zeptometrix | 1 mg | EUR 2026.85 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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) Anti-HTLV Type I p19 Clone 45/6.11.1.3 (1 mg) |
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| 0801108 | Zeptometrix | 1 mg | EUR 2026.85 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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) Anti-HTLV Type II p19 Clone 78/6.18.07 (1 mg) |
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| 0801113 | Zeptometrix | 1 mg | EUR 2026.85 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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 HTLV-I p24 core recombinant antigen |
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| 00204-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HLTV-I p24 core recombinant antigen. |
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HTLV-I p24 core recombinant antigen |
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| 00204-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HLTV-I p24 core recombinant antigen. |
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 HTLV-1 virus mosaic recombinant antigen |
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| 00205-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HTLV-1 virus mosaic recombinant antigen a.a. 374-400/190-207. |
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HTLV-1 virus mosaic recombinant antigen |
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| 00205-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HTLV-1 virus mosaic recombinant antigen a.a. 374-400/190-207. |
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 Antibody) p19 INK4d (p19 INK4d) Antibody |
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| 20-abx119556 | Abbexa |
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p19 INK4d (p19 INK4d) Antibody |
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| abx236065-100ug | Abbexa | 100 ug | EUR 577.2 |
 p19 Antibody |
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| abx034359-400ul | Abbexa | 400 ul | EUR 627.6 |
p19 Antibody |
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| abx034359-80l | Abbexa | 80 µl | EUR 343.2 |
 pSoup+P19 |
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| PVT14690 | Lifescience Market | 2 ug | EUR 1218 |
 Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed |
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| ELISA-1 | Alpha Diagnostics | 1 | EUR 242.4 |
 HTLV 1 ELISA Kit |
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| VArk-Lsx012 | Creative Biolabs | 1 KIT | Ask for price |
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Description: Used for analyzing the presence of the human T-Cell lymphotropic viruses. |
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 SKP1A / p19 Cell ELISA Kit |
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| abx595547-96tests | Abbexa | 96 tests | EUR 764.4 |
 p19 INK4d ELISA KIT|Human |
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| EF001493 | Lifescience Market | 96 Tests | EUR 826.8 |
 p19 Polyclonal Antibody |
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| ABP53464-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of p19 from Human. This p19 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human p19 at AA rangle: 70-150 |
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p19 Polyclonal Antibody |
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| ABP53464-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of p19 from Human. This p19 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human p19 at AA rangle: 70-150 |
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p19 Polyclonal Antibody |
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| ABP53464-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of p19 from Human. This p19 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human p19 at AA rangle: 70-150 |
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 p19 INK4d Antibody |
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| DF13861 | Affbiotech | 100ul | EUR 420 |
p19 Polyclonal Antibody |
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| ES4463-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against p19 from Human. This antibody is tested and validated for IHC, WB, ELISA |
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p19 Polyclonal Antibody |
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| ES4463-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against p19 from Human. This antibody is tested and validated for IHC, WB, ELISA |
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 P19 INK4d antibody |
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| 70R-31779 | Fitzgerald | 100 ug | EUR 392.4 |
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Description: Rabbit polyclonal P19 INK4d antibody |
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 pSoup+p19 Plasmid |
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| PVT3027 | Lifescience Market | 2 ug | EUR 390 |
 Anti-p19 antibody |
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| STJ94861 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Rabbit polyclonal to p19. |
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 anti-p19 INK4d |
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| YF-PA10885 | Abfrontier | 50 ul | EUR 435.6 |
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Description: Mouse polyclonal to p19 INK4d |
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anti-p19 INK4d |
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| YF-PA10886 | Abfrontier | 100 ug | EUR 483.6 |
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Description: Rabbit polyclonal to p19 INK4d |
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 anti-IL23 P19 |
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| YF-PA19119 | Abfrontier | 50 ul | EUR 435.6 |
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Description: Mouse polyclonal to IL23 P19 |
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anti-IL23 P19 |
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| YF-PA19120 | Abfrontier | 50 ug | EUR 435.6 |
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Description: Mouse polyclonal to IL23 P19 |
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anti-IL23 P19 |
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| YF-PA19121 | Abfrontier | 100 ul | EUR 483.6 |
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Description: Rabbit polyclonal to IL23 P19 |
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anti-IL23 P19 |
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| YF-PA19122 | Abfrontier | 100 ug | EUR 483.6 |
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Description: Rabbit polyclonal to IL23 P19 |
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 IL23 p19 Antibody |
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| R30542 | NSJ Bioreagents | 100 ug | EUR 419 |
 Mouse HTLV-1 ELISA Kit |
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| EMH0319 | Abclonal | 96Tests | EUR 625.2 |
 Human HTLV-1 ELISA Kit |
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| EHH0319 | Abclonal | 96Tests | EUR 625.2 |
 Porcine HTLV-1 ELISA Kit |
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| EPH0319 | Abclonal | 96Tests | EUR 625.2 |
 Rat HTLV-1 ELISA Kit |
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| ERH0319 | Abclonal | 96Tests | EUR 625.2 |
 Rabbit HTLV-1 ELISA Kit |
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| ERTH0319 | Abclonal | 96Tests | EUR 625.2 |
 Goat HTLV-1 ELISA Kit |
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| EGTH0319 | Abclonal | 96Tests | EUR 625.2 |
 Bovine HTLV-1 ELISA Kit |
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| EBH0319 | Abclonal | 96Tests | EUR 625.2 |
 Canine HTLV-1 ELISA Kit |
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| ECH0319 | Abclonal | 96Tests | EUR 625.2 |
 Anserine HTLV-1 ELISA Kit |
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| EAH0319 | Abclonal | 96Tests | EUR 625.2 |
 HTLV 1/2 ELISA Kit |
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| VArk-Lsx011 | Creative Biolabs | 1 KIT | Ask for price |
|
Description: Used for analyzing the presence of the human T-Cell lymphotropic viruses. |
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 Human Interleukin 23 p19 ELISA kit |
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| E01I0086-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Human Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Interleukin 23 p19 ELISA kit |
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| E01I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Human Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Interleukin 23 p19 ELISA kit |
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| E01I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Human Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Goat Interleukin 23 p19 ELISA kit |
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| E06I0086-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Goat Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Interleukin 23 p19 ELISA kit |
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| E06I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Goat Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Interleukin 23 p19 ELISA kit |
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| E06I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Goat Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Dog Interleukin 23 p19 ELISA kit |
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| E08I0086-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Canine Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Interleukin 23 p19 ELISA kit |
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| E08I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Canine Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Interleukin 23 p19 ELISA kit |
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| E08I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Canine Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Rabbit Interleukin 23 p19 ELISA kit |
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| E04I0086-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Interleukin 23 p19 ELISA kit |
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| E04I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Interleukin 23 p19 ELISA kit |
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| E04I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Pig Interleukin 23 p19 ELISA kit |
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| E07I0086-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Interleukin 23 p19 ELISA kit |
|||
| E07I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Interleukin 23 p19 ELISA kit |
|||
| E07I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Mouse Interleukin 23 p19 ELISA kit |
|||
| E03I0086-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Mouse Interleukin 23 p19 ELISA kit |
|||
| E03I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Interleukin 23 p19 ELISA kit |
|||
| E03I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Rat Interleukin 23 p19 ELISA kit |
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| E02I0086-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Interleukin 23 p19 ELISA kit |
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| E02I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Interleukin 23 p19 ELISA kit |
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| E02I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
 Monkey Interleukin 23 p19 ELISA kit |
|||
| E09I0086-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Interleukin 23 p19 ELISA kit |
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| E09I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Monkey Interleukin 23 p19 ELISA kit |
|||
| E09I0086-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Skp1 p19 Polyclonal Antibody |
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| ABP52450-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of Skp1 p19 from Human, Mouse, Rat, Monkey. This Skp1 p19 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Skp1 p19 at AA range: 10-90 |
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Skp1 p19 Polyclonal Antibody |
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| ABP52450-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of Skp1 p19 from Human, Mouse, Rat, Monkey. This Skp1 p19 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Skp1 p19 at AA range: 10-90 |
|||
Skp1 p19 Polyclonal Antibody |
|||
| ABP52450-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of Skp1 p19 from Human, Mouse, Rat, Monkey. This Skp1 p19 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Skp1 p19 at AA range: 10-90 |
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 anti- p19 INK4d antibody |
|||
| FNab06065 | FN Test | 100µg | EUR 606.3 |
|
Description: Antibody raised against p19 INK4d |
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Skp1 p19 Polyclonal Antibody |
|||
| ES3449-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against Skp1 p19 from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
Skp1 p19 Polyclonal Antibody |
|||
| ES3449-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against Skp1 p19 from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
 Anti-Skp1 p19 Antibody |
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| A00476-1 | BosterBio | 100ul | EUR 476.4 |
|
Description: Rabbit Polyclonal Antibody for Skp1 p19 Antibody (SKP1) detection.tested for WB in Human, Mouse, Rat, Monkey. |
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 Anti-p19 INK4d antibody |
|||
| PAab06065 | Lifescience Market | 100 ug | EUR 426 |
 Anti-Skp1 p19 antibody |
|||
| STJ95675 | St John's Laboratory | 200 µl | EUR 236.4 |
|
Description: Rabbit polyclonal to Skp1 p19. |
|||
) Anti-p19 INK4d (2E10) |
|||
| YF-MA12390 | Abfrontier | 100 ug | EUR 435.6 |
|
Description: Mouse monoclonal to p19 INK4d |
|||
 p19-INK4d Antibody / CDKN2D |
|||
| F55034-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
p19-INK4d Antibody / CDKN2D |
|||
| F55034-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
 IL-23A Antibody / p19 |
|||
| RQ4068 | NSJ Bioreagents | 100 ug | EUR 419 |
p19-INK4d Antibody / CDKN2D |
|||
| RQ6844 | NSJ Bioreagents | 100ug | EUR 419 |
|
Description: Cyclin-dependent kinase 4 inhibitor D is an enzyme that in humans is encoded by the CDKN2D gene. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. |
|||
 Human T-lymphotropicvirus?,HTLV-?ELISA Kit |
|||
| 201-12-1810 | SunredBio | 96 tests | EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
|||
 Guinea Pig HTLV-1 ELISA Kit |
|||
| EGH0319 | Abclonal | 96Tests | EUR 625.2 |
 Guinea pig Interleukin 23 p19 ELISA kit |
|||
| E05I0086-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Guinea pig Interleukin 23 p19 ELISA kit |
|||
| E05I0086-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Guinea pig Interleukin 23 p19 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
