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Expression of Escherichia coli araE and modified lacY genes in Campylobacter jejuni is not sufficient for arabinose transport

| Steven WashingtonSteven Washington | 0 Comment
stjosephs-hospital

 Introduction: Unlike Escherichia coli , Campylobacter jejuni is unable to import a range of sugars, including arabinose, which makes common expression vectors, such as pBAD33, non-functional in these bacteria.

Aim: The aim of this study was to investigate whether the E. coli transporters AraE and modified LacY (LacYA177C) would enable C. jejuni to uptake arabinose.

Methodology and results: The respective genes of E. coli were constitutively expressed in C. jejuni strain 11168H after integration into the chromosome via homologous recombination. Vectors carrying these genes also contained a reporter gene, gfp, under the control of the arabinose-inducible promoter, pBAD. These constructs were verified in E. coli by demonstrating the induction of gfp in the presence of arabinose.

Integration of the genes into one of the rRNA gene clusters was verified by PCR and genome sequencing. The latter also confirmed that the inserted gene clusters contained no mutations. Expression of the gfp gene in the presence of arabinose inducer was monitored using fluorescence microscopy of colonies and fluorimetry using both whole cells and lysates.

Conclusion: The results demonstrated the inability of C. jejuni to use arabinose transporters, which are fully functional in E. coli , suggesting a remarkable difference in the physiology of these bacteria.

 

Genome-Wide Analysis of Peptidoglycan Recognition Protein Genes in Fig Wasps (Hymenoptera, Chalcidoidea)

 

  • The innate immunity is the most important defense against pathogen of insects, and the peptidoglycan recognition proteins (PGRPs) play an important role in the processes of immune recognition and initiation of Toll, IMD and other signal pathways. In fig wasps, pollinators and non-pollinators present different evolutionary histories and lifestyles, even though both are closely associated with fig syconia, which may indicate their different patterns in the evolution of PGRPs.
  • By manual annotation, we got all the PGRP genes of 12 fig wasp species, containing seven pollinators and five non-pollinators, and investigated their putative different evolutionary patterns. We found that the number of PGRP genes in pollinators was significantly lower than in non-pollinators, and the number of catalytic PGRP presented a declining trend in pollinators.
  • More importantly, PGRP-SA is associated with initiating the Toll pathway, as well as gram-negative bacteria-binding proteins (GNBPs), which were completely lost in pollinators, which led us to speculate that the initiation of Toll pathway was simpler in pollinators than in non-pollinators.
  • We concluded that fig pollinators owned a more streamlined innate immune recognition system than non-pollinators. Our results provide molecular evidence for the adaptive evolution of innate immunity in insects of host specificity.

 

Comparative genomics of Alexander Fleming’s original Penicillium isolate (IMI 15378) reveals sequence divergence of penicillin synthesis genes 

Antibiotics were derived originally from wild organisms and therefore understanding how these compounds evolve among different lineages might help with the design of new antimicrobial drugs. We report the draft genome sequence of Alexander Fleming’s original fungal isolate behind the discovery of penicillin, now classified as Penicillium rubens Biourge (1923) (IMI 15378). We compare the structure of the genome and genes involved in penicillin synthesis with those in two ‘high producing’ industrial strains of P. rubens and the closely related species P. nalgiovense.

The main effector genes for producing penicillin G (pcbAB, pcbC and penDE) show amino acid divergence between the Fleming strain and both industrial strains, whereas a suite of regulatory genes are conserved. Homologs of penicillin N effector genes cefD1 and cefD2 were also found and the latter displayed amino acid divergence between the Fleming strain and industrial strains.

The draft assemblies contain several partial duplications of penicillin-pathway genes in all three P. rubens strains, to differing degrees, which we hypothesise might be involved in regulation of the pathway. The two industrial strains are identical in sequence across all effector and regulatory genes but differ in duplication of the pcbAB-pcbC-penDE complex and partial duplication of fragments of regulatory genes. We conclude that evolution in the wild encompassed both sequence changes of the effector genes and gene duplication, whereas human-mediated changes through mutagenesis and artificial selection led to duplication of the penicillin pathway genes.

stjosephs-hospital

stjosephs-hospital

Transposon Insertion in the purL Gene Induces Biofilm Depletion in Escherichia coli ATCC 25922

Current Escherichia coli antibiofilm treatments comprise a combination of antibiotics commonly used against planktonic cells, leading to treatment failure. A better understanding of the genes involved in biofilm formation could facilitate the development of efficient and specific new antibiofilm treatments.

A total of 2578 E. coli mutants were generated by transposon insertion, of which 536 were analysed in this study. After sequencing, Tn263 mutant, classified as low biofilm-former (LF) compared to the wild-type (wt) strain (ATCC 25922), showed an interruption in the purL gene, involved in the de novo purine biosynthesis pathway.

To elucidate the role of purL in biofilm formation, a knockout was generated showing reduced production of curli fibres, leading to an impaired biofilm formation. These conditions were restored by complementation of the strain or addition of exogenous inosine. Proteomic and transcriptional analyses were performed to characterise the differences caused by purL alterations.

Thirteen proteins were altered compared to wt. The corresponding genes were analysed by qRT-PCR not only in the Tn263 and wt, but also in clinical strains with different biofilm activity. Overall, this study suggests that purL is essential for biofilm formation in E. coli and can be considered as a potential antibiofilm target.

 

Characterizing patient-oncologist communication in genomic tumor testing: The 21-gene recurrence score as an exemplar

Objective: Women with early-stage, ER + breast cancer are recommend to receive genomic profiling tests, such as the 21-gene Recurrence Score (RS) test, to guide treatment decisions. We examined test- and treatment-related information discussed and the associations between RS categories and aspects of communication during patient-oncologist clinical encounters.

Methods: As part of a larger trial, clinical encounters (N = 46) were audiorecorded and coded for 1) RS- and treatment-related information, 2) shared decision making, 3) patient active participation, and 4) oncologist patient-centered communication. We examined differences by RS category using mixed models, adjusting for nesting within oncologist.

Results: Patients with a high RS were more likely to receive a chemotherapy recommendation (p < .01), hear about the risks/side effects of chemotherapy (p < .01), and offer their preferences (p = .02) than those with intermediate or low RS. Elements of shared decision making increased with RS. Oncologist patient-centered communication (M = 4.09/5, SD = .25) and patient active participation (M = 3.5/4, SD = 1.0) were high across RS.

Conclusion: Findings suggest that disease severity, rather than clinical uncertainty, impact treatment recommendations and shared decision making.

Practice implications: Oncologists adjust test- and treatment-related information and shared decision making by disease severity. This information provides a framework to inform decision making in complex cancer and genomics settings.

 

ACTN3 Antibody

ABD7803 Lifescience Market 100 ug
EUR 525.6

ACTN3 Antibody

ABD8016 Lifescience Market 100 ug
EUR 525.6

ACTN3 Antibody

DF8016 Affbiotech 200ul
EUR 420

ACTN3 Antibody

1-CSB-PA124802 Cusabio
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000

ACTN3 Antibody

1-CSB-PA288460 Cusabio
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000

ACTN3 Antibody

1-CSB-PA000816 Cusabio
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/20000

ACTN3 Antibody

1-CSB-PA001243LA01HU Cusabio
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

ACTN3 antibody

PAab10008 Lifescience Market 100 ug
EUR 463.2

ACTN3 Antibody

R32494 NSJ Bioreagents 100 ug
EUR 356.15
Description: Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

ACTN2 / ACTN3 Antibody

abx332374-100ul Abbexa 100 ul
EUR 510

ACTN2 / ACTN3 Antibody

20-abx329446 Abbexa
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

ACTN2/ACTN3 Antibody

CSB-PA960396- Cusabio each
EUR 402
Description: A polyclonal antibody against ACTN2/ACTN3. Recognizes ACTN2/ACTN3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

ACTN2/ACTN3 Antibody

CSB-PA960396-100ul Cusabio 100ul
EUR 379.2
Description: A polyclonal antibody against ACTN2/ACTN3. Recognizes ACTN2/ACTN3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

ACTN2/ACTN3 Antibody

1-CSB-PA000815 Cusabio
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN2/ACTN3. Recognizes ACTN2/ACTN3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

Polyclonal ACTN3 Antibody

APR14796G Leading Biology 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTN3 . This antibody is tested and proven to work in the following applications:

ACTN1 / ACTN2 / ACTN3 / ACTN4 Antibody

abx332562-100ul Abbexa 100 ul
EUR 510

ACTN1 / ACTN2 / ACTN3 / ACTN4 Antibody

20-abx328684 Abbexa
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

ACTN1/ACTN2/ACTN3/ACTN4 Antibody

CSB-PA096347- Cusabio each
EUR 402
Description: A polyclonal antibody against ACTN1/ACTN2/ACTN3/ACTN4. Recognizes ACTN1/ACTN2/ACTN3/ACTN4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ACTN1/ACTN2/ACTN3/ACTN4 Antibody

CSB-PA096347-100ul Cusabio 100ul
EUR 379.2
Description: A polyclonal antibody against ACTN1/ACTN2/ACTN3/ACTN4. Recognizes ACTN1/ACTN2/ACTN3/ACTN4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ACTN1/ACTN2/ACTN3/ACTN4 Antibody

1-CSB-PA000814 Cusabio
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN1/ACTN2/ACTN3/ACTN4. Recognizes ACTN1/ACTN2/ACTN3/ACTN4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

ACTN3 Conjugated Antibody

C34157 SAB 100ul
EUR 476.4

ACTN3 Antibody, HRP conjugated

1-CSB-PA001243LB01HU Cusabio
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

ACTN3 Antibody, FITC conjugated

1-CSB-PA001243LC01HU Cusabio
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Polyclonal ACTN3 Antibody (Center)

APR14798G Leading Biology 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTN3 (Center). This antibody is tested and proven to work in the following applications:

ACTN3 Antibody, Biotin conjugated

1-CSB-PA001243LD01HU Cusabio
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ACTN3. Recognizes ACTN3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Actinin Alpha 3 (ACTN3) Antibody

abx230122-100ug Abbexa 100 ug
EUR 610.8

Alpha Actinin 3 (ACTN3) Antibody

20-abx213418 Abbexa
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Alpha Actinin 3 (ACTN3) Antibody

20-abx213419 Abbexa
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Actinin Alpha 3 (ACTN3) Antibody

abx026732-400ul Abbexa 400 ul
EUR 627.6

Actinin Alpha 3 (ACTN3) Antibody

abx026732-80l Abbexa 80 µl
EUR 343.2

Actinin Alpha 3 (ACTN3) Antibody

20-abx013892 Abbexa
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Actinin Alpha 3 (ACTN3) Antibody

abx038105-100ug Abbexa 100 ug
EUR 469.2

Actinin Alpha 3 (ACTN3) Antibody

20-abx130639 Abbexa
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Alpha Actinin 3 (ACTN3) Antibody

20-abx328117 Abbexa
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Actinin Alpha 3 (ACTN3) Antibody

20-abx009624 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

ACTN3 Antibody / Alpha Actinin 3

RQ4625 NSJ Bioreagents 100ug
EUR 356.15
Description: Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

Polyclonal ACTN3 Antibody (aa1-50)

APR14797G Leading Biology 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTN3 (aa1-50). This antibody is tested and proven to work in the following applications:

Anti-Human ACTN3 DyLight® 488 conjugated Antibody

A02693-Dyl488 BosterBio 100ug/vial
EUR 412.8

Anti-Human ACTN3 DyLight® 550 conjugated Antibody

A02693-Dyl550 BosterBio 100ug/vial
EUR 412.8

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human)

4-PAB104Hu01 Cloud-Clone
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3)

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), PE

4-PAB104Hu01-PE Cloud-Clone
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with PE.

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), APC

4-PAB104Hu01-APC Cloud-Clone
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with APC.

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), Cy3

4-PAB104Hu01-Cy3 Cloud-Clone
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with Cy3.

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), HRP

4-PAB104Hu01-HRP Cloud-Clone
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with HRP.

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), FITC

4-PAB104Hu01-FITC Cloud-Clone
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with FITC.

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), Biotinylated

4-PAB104Hu01-Biotin Cloud-Clone
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with Biotin.

Actinin Alpha 3 (ACTN3) Polyclonal Antibody (Human), APC-Cy7

4-PAB104Hu01-APC-Cy7 Cloud-Clone
  • EUR 656.40
  • EUR 7327.20
  • EUR 1948.80
  • EUR 872.40
  • EUR 372.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Actinin Alpha 3 (ACTN3). This antibody is labeled with APC-Cy7.

ACTN3 siRNA

20-abx906644 Abbexa
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

ACTN3 siRNA

20-abx906645 Abbexa
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti- ACTN2 antibody

FNab00121 FN Test 100µg
EUR 606.3
Description: Antibody raised against ACTN2

anti- ACTN4 antibody

FNab00123 FN Test 100µg
EUR 606.3
Description: Antibody raised against ACTN4

ACTN3 Rabbit pAb

A12797-100ul Abclonal 100 ul
EUR 369.6

ACTN3 Rabbit pAb

A12797-200ul Abclonal 200 ul
EUR 550.8

ACTN3 Rabbit pAb

A12797-20ul Abclonal 20 ul
EUR 219.6

ACTN3 Rabbit pAb

A12797-50ul Abclonal 50 ul
EUR 267.6

ACTN3 Rabbit pAb

A12864-100ul Abclonal 100 ul
EUR 369.6

ACTN3 Rabbit pAb

A12864-200ul Abclonal 200 ul
EUR 550.8

ACTN3 Rabbit pAb

A12864-20ul Abclonal 20 ul
EUR 219.6

ACTN3 Rabbit pAb

A12864-50ul Abclonal 50 ul
EUR 267.6

ACTN3 Blocking Peptide

20-abx062207 Abbexa
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

ACTN3 Blocking Peptide

DF8016-BP Affbiotech 1mg
EUR 234

Rat ACTN3 ELISA Kit

ERA0390 Abclonal 96Tests
EUR 625.2

Goat ACTN3 ELISA Kit

EGTA0390 Abclonal 96Tests
EUR 625.2

Mouse ACTN3 ELISA Kit

EMA0390 Abclonal 96Tests
EUR 625.2

Human ACTN3 ELISA Kit

ELA-E1104h Lifescience Market 96 Tests
EUR 988.8

ACTN3 ELISA KIT|Human

EF003149 Lifescience Market 96 Tests
EUR 826.8

Human ACTN3 ELISA Kit

EHA0390 Abclonal 96Tests
EUR 625.2

Rabbit ACTN3 ELISA Kit

ERTA0390 Abclonal 96Tests
EUR 625.2

Bovine ACTN3 ELISA Kit

EBA0390 Abclonal 96Tests
EUR 625.2

Canine ACTN3 ELISA Kit

ECA0390 Abclonal 96Tests
EUR 625.2

Porcine ACTN3 ELISA Kit

EPA0390 Abclonal 96Tests
EUR 625.2

Anserini ACTN3 ELISA Kit

EAA0390 Abclonal 96Tests
EUR 625.2

Human ACTN3 shRNA Plasmid

20-abx950055 Abbexa
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse ACTN3 shRNA Plasmid

20-abx969019 Abbexa
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Anti-ACTN3 Antibody

PB10026 BosterBio 100ug/vial
EUR 400.8

Anti-ACTN3 antibody

PAab00122 Lifescience Market 100 ug
EUR 463.2

Anti-ACTN3 antibody

STJ114663 St John's Laboratory 100 µl
EUR 332.4
Description: This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

Anti-ACTN3 antibody

STJ114730 St John's Laboratory 100 µl
EUR 332.4
Description: This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

Anti-Alpha Actinin 4/ACTN4 Antibody

PB9974 BosterBio 100ug/vial
EUR 400.8

Actn3 ORF Vector (Rat) (pORF)

ORF063016 ABM 1.0 ug DNA
EUR 607.2

Guinea Pig ACTN3 ELISA Kit

EGA0390 Abclonal 96Tests
EUR 625.2

ACTN3 ORF Vector (Human) (pORF)

ORF012141 ABM 1.0 ug DNA
EUR 424.8

Actn3 ORF Vector (Mouse) (pORF)

ORF038023 ABM 1.0 ug DNA
EUR 607.2

ACTN3 ELISA Kit (Human) (OKEH04449)

OKEH04449 Aviva Systems Biology 96 Wells
EUR 794.4
Description: Description of target: This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 4.1 pg/mL

ACTN3 ELISA Kit (Mouse) (OKEH05687)

OKEH05687 Aviva Systems Biology 96 Wells
EUR 794.4
Description: Description of target: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 41 pg/mL

Recombinant Actinin Alpha 3 (ACTN3)

4-RPB104Hu01 Cloud-Clone
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Actinin Alpha 3 expressed in: E.coli

Actinin Alpha 3 (ACTN3) CLIA Kit

20-abx492418 Abbexa
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Actinin Alpha 3 (ACTN3) ELISA Kit

20-abx156912 Abbexa
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Actinin Alpha 3 (ACTN3) Protein

20-abx167185 Abbexa
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Actn3 sgRNA CRISPR Lentivector set (Rat)

K6966901 ABM 3 x 1.0 ug
EUR 406.8
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