The dissection of R genes and locus Pc5.1 in Phytophthora capsici infection provides a novel view of disease resistance in peppers

stjosephs-hospital

Background: Phytophthora capsici root rot (PRR) is a disastrous disease in peppers (Capsicum spp.) caused by soilborne oomycete with typical symptoms of necrosis and constriction at the basal stem and consequent plant wilting.

 

Most studies on the QTL mapping of P. capsici resistance suggested a consensus broad-spectrum QTL on chromosome 5 named Pc.5.1 regardless of P. capsici isolates and resistant resources. In addition, all these reports proposed NBS-ARC domain genes as candidate genes controlling resistance.

Results: We screened out 10 PRR-resistant resources from 160 Capsicum germplasm and inspected the response of locus Pc.5.1 and NBS-ARC genes during P. capsici infection by comparing the root transcriptomes of resistant pepper 305R and susceptible pepper 372S.

 

To dissect the structure of Pc.5.1, we anchored genetic markers onto pepper genomic sequence and made an extended Pc5.1 (Ext-Pc5.1) located at 8.35 Mb-38.13 Mb on chromosome 5 which covered all Pc5.1 reported in publications.

A total of 571 NBS-ARC genes were mined from the genome of pepper CM334 and 34 genes were significantly affected by P. capsici infection in either 305R or 372S. Only 5 inducible NBS-ARC genes had LRR domains and none of them was positioned at Ext-Pc5.1. Ext-Pc5.1 did show strong response to P. capsici infection and there were a total of 44 differentially expressed genes (DEGs), but no candidate genes proposed by previous publications was included. Snakin-1 (SN1), a well-known antimicrobial peptide gene located at Pc5.1, was significantly decreased in 372S but not in 305R.

Moreover, there was an impressive upregulation of sugar pathway genes in 305R, which was confirmed by metabolite analysis of roots. The biological processes of histone methylation, histone phosphorylation, DNA methylation, and nucleosome assembly were strongly activated in 305R but not in 372S, indicating an epigenetic-related defense mechanism.

Conclusions: Those NBS-ARC genes that were suggested to contribute to Pc5.1 in previous publications did not show any significant response in P. capsici infection and there were no significant differences of these genes in transcription levels between 305R and 372S.

 

Other pathogen defense-related genes like SN1 might account for Pc5.1. Our study also proposed the important role of sugar and epigenetic regulation in the defense against P. capsici.

 

Bioinformatics analysis and identification of genes and molecular pathways in steroid-induced osteonecrosis of the femoral head

 

Background: Steroid-induced osteonecrosis of the femoral head (ONFH) is a common hip joint disease and is difficult to be diagnosed early. At present, the pathogenesis of steroid-induced ONFH remains unclear, and recognized and effective diagnostic biomarkers are deficient. The present study aimed to identify potentially important genes and signaling pathways involved in steroid-induced ONFH and investigate their molecular mechanisms.

 

Methods: Microarray data sets GSE123568 (peripheral blood) and GSE74089 (cartilage) were obtained from the Gene Expression Omnibus database, including 34 ONFH samples and 14 control samples. Morpheus software and Venn diagram were used to identify DEGs and co-expressed DEGs, respectively. Besides, we conducted Kyoto Encyclopedia of Genome (KEGG) and gene ontology (GO) pathway enrichment analysis.

We construct a protein-protein interaction (PPI) network through GEO2R and used cytoHubba to divide the PPI network into multiple sub-networks. Additionally, quantitative real-time polymerase chain reaction (qRT-PCR) was performed to verify the bioinformatics analysis results.

Results: A total of 118 intersecting DEGs were obtained between the peripheral blood and cartilage samples, including 40 upregulated genes and 78 downregulated genes. Then, GO and KEGG pathway enrichment analysis revealed that upregulated DEGs focused on the signaling pathways related to staphylococcus aureus infection, leishmaniasis, antigen processing, and presentation, as well as asthma and graft-versus-host disease.

Downregulated genes were concentrated in the FoxO signaling pathway, AMPK signaling pathway, signaling pathway regulating stem cell pluripotency, and mTOR signaling pathway. Some hub genes with high interactions such as CXCR1, FPR1, MAPK1, FOXO3, FPR2, CXCR2, and TYROBP were identified in the PPI network.

The results of qRT-PCR demonstrated that CXCR1, FPR1, and TYROBP were upregulated while MAPK1 was downregulated in peripheral blood of steroid-induced ONFH patients. This was consistent with the bioinformatics analysis.

Conclusions: The present study would provide novel insight into the genes and associated pathways involved in steroid-induced ONFH. CXCR1, FPR1, TYROBP, and MAPK1 may be used as potential drug targets and biomarkers for the diagnosis and prognosis of steroid-induced ONFH.

stjosephs-hospital

stjosephs-hospital

Cultural Evolution of Genetic Heritability

Behavioral genetics and cultural evolution have both revolutionized our understanding of human behavior-largely independent of each other. Here we reconcile these two fields under a dual inheritance framework, offering a more nuanced understanding of the interaction between genes and culture.

Going beyond typical analyses of gene-environment interactions, we describe the cultural dynamics that shape these interactions by shaping the environment and population structure. A cultural evolutionary approach can explain, for example, how factors such as rates of innovation and diffusion, density of cultural sub-groups, and tolerance for behavioral diversity impact heritability estimates, thus yielding predictions for different social contexts.

  • Moreover, when cumulative culture functionally overlaps with genes, genetic effects become masked, unmasked, or even reversed, and the causal effects of an identified gene become confounded with features of the cultural environment.
  • The manner of confounding is specific to a particular society at a particular time, but a WEIRD (Western, educated, industrialized, rich, democratic) sampling problem obscures this boundedness.
  • Cultural evolutionary dynamics are typically missing from models of gene-to-phenotype causality, hindering generalizability of genetic effects across societies and across time.
  • We lay out a reconciled framework and use it to predict the ways in which heritability should differ between societies, between socioeconomic levels and other groupings within some societies but not others, and over the life course.
  • An integrated cultural evolutionary behavioral genetic approach cuts through the nature-nurture debate and helps resolve controversies in topics such as IQ.

anti- NFKB1 antibody

FNab05702 100µg
EUR 606.3
Description: Antibody raised against NFKB1

anti- NFKB1 antibody

FNab05703 100µg
EUR 702
Description: Antibody raised against NFKB1

anti- NFKB2 antibody

FNab05705 100µg
EUR 606.3
Description: Antibody raised against NFKB2

anti- NFKB2 antibody

FNab05706 100µg
EUR 658.5
Description: Antibody raised against NFKB2

Human Transcription factor p65 protein (NFKB3)

1-CSB-RP039844h
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Transcription factor p65 protein(NFKB3),partial expressed in E.coli

Human Transcription factor p65 protein (NFKB3)

1-CSB-RP039874h
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Transcription factor p65 protein(NFKB3),partial expressed in E.coli

Anti-NFkB p105/p50/NFKB1 Antibody

PB9149 100ug/vial
EUR 400.8

Anti-NFkB p100/p52/NFKB2 Antibody

PB9150 100ug/vial
EUR 400.8

Anti-NFkB p100/p52/NFKB2 Antibody

PA1946 100ug/vial
EUR 400.8

Anti-NFkB p100/p52/NFKB2 Antibody

PA1946-1 100ug/vial
EUR 352.8

Anti-NFkB p105/p50/NFKB1 Antibody

PA2111 100ug/vial
EUR 352.8

Anti-NFkB p105/p50/NFKB1 Antibody

PA2111-1 100ug/vial
EUR 352.8

anti- NFKB1,p105,p50-Specific antibody

FNab05704 100µg
EUR 702
Description: Antibody raised against NFKB1,p105,p50-Specific

anti- NFKB2,p52,p100-Specific antibody

FNab05707 100µg
EUR 658.5
Description: Antibody raised against NFKB2,p52,p100-Specific

anti- NFKBIE antibody

FNab05708 100µg
EUR 658.5
Description: Antibody raised against NFKBIE

anti- NFKBIZ antibody

FNab05709 100µg
EUR 606.3
Description: Antibody raised against NFKBIZ

Rat Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx255851-96tests 96 tests
EUR 801.6

Pig Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx361108-96tests 96 tests
EUR 990

Rat Transcription factor p65 / NFKB3 (RELA) ELISA Kit

20-abx156040
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx254289-96tests 96 tests
EUR 801.6

Human Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx252815-96tests 96 tests
EUR 801.6

Sheep Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx364265-96tests 96 tests
EUR 1111.2

Mouse Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx570127-96tests 96 tests
EUR 801.6

Human Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx570125-96tests 96 tests
EUR 801.6

Human Transcription factor p65 / NFKB3 (RELA) ELISA Kit

20-abx152945
  • EUR 7970.40
  • EUR 4250.40
  • EUR 990.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rabbit Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx362582-96tests 96 tests
EUR 990

Monkey Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx359107-96tests 96 tests
EUR 990

Rabbit Anti-Human NFKB1 (aa 930-934) Polyclonal Antibody

CPB-1129RH 100 ul
EUR 552

Rabbit Anti-Human NFKB1 (aa 160-170) Polyclonal Antibody

CPB-1169RH 100 ul
EUR 552

Rabbit Anti-Human NFKB2 (aa 160-171) Polyclonal Antibody

CPB-1176RH 100 ul
EUR 552

Chicken Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx357192-96tests 96 tests
EUR 990

Guinea pig Transcription factor p65 / NFKB3 (RELA) ELISA Kit

abx357262-96tests 96 tests
EUR 990

Rabbit Anti-Human NFKB2 Polyclonal Antibody, aa.864-868

CPB-930RH 100 ul
EUR 552

Rabbit Anti-Human NFKB2 Polyclonal Antibody, aa.868-872

CPB-931RH 100 ul
EUR 552

Rabbit Anti-Human NFKB1 Polyclonal Antibody, aa.335-339

CPB-932RH 100 ul
EUR 552

Rabbit Anti-Human NFKB1 Polyclonal Antibody, aa.891-895

CPB-933RH 100 ul
EUR 552

Rabbit Anti-Human NFKB1 Polyclonal Antibody, aa.905-909

CPB-934RH 100 ul
EUR 552

NFKB1 antibody

10R-11003 100 ug
EUR 418.8
Description: Mouse monoclonal NFKB1 antibody

NFKB1 antibody

10R-11155 100 ug
EUR 418.8
Description: Mouse Monoclonal NFKB1 antibody

NFKB2 antibody

10R-1605 100 ug
EUR 614.4
Description: Mouse monoclonal NFKB2 antibody

NFKB1 antibody

20-PR03 100 ul
EUR 682.8
Description: Rabbit polyclonal NFKB1 antibody

NFKB2 antibody

38583-100ul 100ul
EUR 302.4

NFKB2 Antibody

37182-100ul 100ul
EUR 302.4

NFKB1 antibody

39087-100ul 100ul
EUR 302.4

NFKB1 Antibody

BF0466 200ul
EUR 540

NFKB1 antibody

70R-10525 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal NFKB1 antibody

NFKB1 antibody

70R-18860 50 ul
EUR 522
Description: Rabbit polyclonal NFKB1 antibody

NFKB2 antibody

70R-18861 50 ul
EUR 522
Description: Rabbit polyclonal NFKB2 antibody

NFKB1 antibody

70R-15433 100 ug
EUR 392.4
Description: Rabbit polyclonal NFKB1 antibody

NFKB1 Antibody

35588-100ul 100ul
EUR 302.4

NFKB2 Antibody

ABD7190 100 ug
EUR 525.6

NFKB2 Antibody

1-CSB-PA003428
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.IF:1/200-1/1000.ELISA:1/20000

NFKB2 Antibody

1-CSB-PA003429
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

NFKB1 Antibody

1-CSB-PA003430
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/10000

NFKB1 Antibody

1-CSB-PA003431
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000

NFKB1 Antibody

1-CSB-PA003434
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000

NFKB1 Antibody

1-CSB-PA004763
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA10354A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, ChIP; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500

NFKB2 Antibody

1-CSB-PA10449A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

NFKB1 Antibody

1-CSB-PA259078
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:5000, IHC:1:5-1:20

NFKB2 Antibody

1-CSB-PA821156
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:10000, WB:1:1000-1:5000

NFKB2 Antibody

1-CSB-PA785439
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:15-1:50

NFKB2 Antibody

1-CSB-PA015760GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB

NFKB1 Antibody

1-CSB-PA020085
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA020086
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/5000

NFKB1 Antibody

1-CSB-PA020090
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA020096
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

NFKB1 Antibody

1-CSB-PA015759GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

NFKB1 Antibody

1-CSB-PA441503
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000

NFKB1 Antibody

1-CSB-PA546304
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:5000, IHC:1:25-1:100

NFKB1 Antibody

F52441-0.4ML 0.4 ml
EUR 330.65
Description: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NFkB is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NFkB complexes are held in the cytoplasm in an inactive state complexed with members of the NFkB inhibitor (I-kappa-B) family. In a conventional activation pathway, IkB is phosphorylated by IkB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NFkB complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NFkB p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NFkB proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally. p50 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. In a complex with MAP3K8, NFKB1/p105 represses MAP3K8-induced MAPK signaling; active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105.

NFKB1 Antibody

F54028-0.1ML 0.1 ml
EUR 322.15
Description: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. [UniProt]

NFKB1 Antibody

F47079-0.4ML 0.4 ml
EUR 322.15
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

NFKB2 Antibody

F47541-0.4ML 0.4 ml
EUR 322.15
Description: NF-kappa-B has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-kappa-B is activated by a wide variety of stimuli, such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. NFKB1 (MIM 164011) and NFKB2 encode p105 and p100 proteins that are processed to produce the active p50 and p52 NF-kappa-B subunits, respectively. However, the p100 and p105 proteins serve regulatory functions and should not be considered exclusively as precursor forms. The most abundant activated form of NF-kappa-B is a heterodimer of the p50 or p52 subunit bound to the RELA subunit (MIM 164014). Other NF-kappa-B complexes, consisting of hetero- and homodimers of p50, p52, RELA, REL (MIM 164910), and RELB (MIM 604758), have also been detected. NF-kappa-B complexes are inhibited by I-kappa-B proteins, NFKBIA (MIM 164008) or NFKBIB (MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by the kinases IKBKA (CHUK; MIM 600664) or IKBKB (MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. The activated NF-kappa-B complex translocates into the nucleus and binds DNA at kappa-B-binding motifs, such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].

NFKB1 Antibody

R20321-0.1ML 100ul
EUR 347.65
Description: This antibody reacts to human nuclear factor-kappa-B p105 subunit and p50 subunit.

NFKB2 Antibody

R31047 100 ug
EUR 356.15
Description: Nuclear Factor Kappa-B, Subunit 2, also known as NFKB or p52/p100 subunit, is a protein that in humans is encoded by the NFKB2 gene. Liptay et al.(1992) mapped the gene for what they called the p49/p100 subunit of NFKB to chromosome 10 by Southern blot analysis of panels of human/Chinese hamster cell hybrids. By fluorescence in situ hybridization(FISH), they confirmed the localization and mapped the gene with greater resolution to 10q24. NFKB2 appears to be the same as LYT10. Claudio et al.(2002) showed that bone marrow(BM) cells from Nfkb2-deficient mice, but not Nfkb1-deficient mice, failed to increase relative and total IgD-positive transitional-1(T1) stage B cells in response to Baff. In vivo, however, Nfkb2-deficient mice did generate mature B cells, but at reduced numbers. Mice of the aly/aly strain, which are naturally deficient in Nik, and mice of the A/WySNJ strain, which have a mutation in Baffr, also failed to produce T1 B cells in response to Baff. Baff stimulation enhanced expression of Bcl2 in T1 B cells, thereby promoting B-cell survival, and caused the processing of the p100 form of the protein to p52, which again required Baffr and Nik, but not Nemo(IKKG). Immunoblot analysis showed that BM cells contained primarily p100.

NFKB1 Antibody

R31224 100 ug
EUR 356.15
Description: Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing.

NFKB2 Antibody

R31570 100 ug
EUR 356.15
Description: Nuclear factor kappa-B subunit 2 is a protein that in humans is encoded by the NFKB2 gene. It is mapped to 10q24.32. This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFKB). NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner.

NFKB1 antibody (HRP)

60R-2109 100 ug
EUR 392.4
Description: Rabbit polyclonal NFKB1 antibody (HRP)

NFKB1 antibody (FITC)

60R-2110 100 ug
EUR 392.4
Description: Rabbit polyclonal NFKB1 antibody (FITC)

NFKB1 Antibody (p105)

F52441-0.08ML 0.08 ml
EUR 140.25
Description: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NFkB is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NFkB complexes are held in the cytoplasm in an inactive state complexed with members of the NFkB inhibitor (I-kappa-B) family. In a conventional activation pathway, IkB is phosphorylated by IkB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NFkB complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NFkB p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NFkB proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally. p50 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. In a complex with MAP3K8, NFKB1/p105 represses MAP3K8-induced MAPK signaling; active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105.

NFKB1 Antibody (p105)

F47079-0.08ML 0.08 ml
EUR 140.25
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Anti-IKB beta/NFKBIB Antibody

PB9292 100ug/vial
EUR 400.8

NFKB1 Antibody NF-kB p105/p50

R31223 100 ug
EUR 356.15
Description: NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing.

NFKB1 antibody (biotin)

60R-2111 100 ug
EUR 392.4
Description: Rabbit polyclonal NFKB1 antibody (biotin)

Anti-IKB alpha/NFKBIA Antibody

PB9291 100ug/vial
EUR 400.8

Rabbit Anti-Human NFKB1 Polyclonal Antibody, Phospho-Ser932

CPB-782RH 100 ul
EUR 670.8

Rabbit Anti-Human NFKB1 Polyclonal Antibody, Phospho-Ser927

CPB-827RH 100 ul
EUR 670.8

NFKB2 (p100) Antibody

F47541-0.08ML 0.08 ml
EUR 140.25
Description: NF-kappa-B has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-kappa-B is activated by a wide variety of stimuli, such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. NFKB1 (MIM 164011) and NFKB2 encode p105 and p100 proteins that are processed to produce the active p50 and p52 NF-kappa-B subunits, respectively. However, the p100 and p105 proteins serve regulatory functions and should not be considered exclusively as precursor forms. The most abundant activated form of NF-kappa-B is a heterodimer of the p50 or p52 subunit bound to the RELA subunit (MIM 164014). Other NF-kappa-B complexes, consisting of hetero- and homodimers of p50, p52, RELA, REL (MIM 164910), and RELB (MIM 604758), have also been detected. NF-kappa-B complexes are inhibited by I-kappa-B proteins, NFKBIA (MIM 164008) or NFKBIB (MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by the kinases IKBKA (CHUK; MIM 600664) or IKBKB (MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. The activated NF-kappa-B complex translocates into the nucleus and binds DNA at kappa-B-binding motifs, such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].

NFKB1p105 Antibody

35587-100ul 100ul
EUR 302.4

NFKB2 (pS872) Antibody

abx333034-100ul 100 ul
EUR 560.4

NFKB1 (pS337) Antibody

20-abx000177
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS927) Antibody

20-abx000315
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS893) Antibody

20-abx000462
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS907) Antibody

20-abx000463
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 (pS932) Antibody

20-abx000464
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB2 (pS866) Antibody

20-abx000465
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB2 (pS870) Antibody

20-abx000466
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

NFKB1 Antibody, HRP conjugated

1-CSB-PA10354B0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

NFKB2 Antibody, HRP conjugated

1-CSB-PA10449B0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Polyclonal NFKB1 Antibody (S932)

APR04474G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NFKB1 (S932). This antibody is tested and proven to work in the following applications:

NFKB1 Antibody, FITC conjugated

1-CSB-PA10354C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NFKB2 Antibody, FITC conjugated

1-CSB-PA10449C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NFKB2. Recognizes NFKB2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NFKB2 (Ab-870) Antibody

CSB-PA178291- each
EUR 402
Description: A polyclonal antibody against NFKB2 (Ab-870). Recognizes NFKB2 (Ab-870) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB2 (Ab-870) Antibody

CSB-PA178291-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB2 (Ab-870). Recognizes NFKB2 (Ab-870) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-337) Antibody

CSB-PA186775- each
EUR 402
Description: A polyclonal antibody against NFKB1 (Ab-337). Recognizes NFKB1 (Ab-337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-337) Antibody

CSB-PA186775-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB1 (Ab-337). Recognizes NFKB1 (Ab-337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-932) Antibody

CSB-PA190132- each
EUR 402
Description: A polyclonal antibody against NFKB1 (Ab-932). Recognizes NFKB1 (Ab-932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-932) Antibody

CSB-PA190132-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB1 (Ab-932). Recognizes NFKB1 (Ab-932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-893) Antibody

CSB-PA108426- each
EUR 402
Description: A polyclonal antibody against NFKB1 (Ab-893). Recognizes NFKB1 (Ab-893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-893) Antibody

CSB-PA108426-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB1 (Ab-893). Recognizes NFKB1 (Ab-893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB2 (Ab-872) Antibody

CSB-PA274947- each
EUR 402
Description: A polyclonal antibody against NFKB2 (Ab-872). Recognizes NFKB2 (Ab-872) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

NFKB2 (Ab-872) Antibody

CSB-PA274947-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB2 (Ab-872). Recognizes NFKB2 (Ab-872) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

NFKB1 (Ab-907) Antibody

CSB-PA696291- each
EUR 402
Description: A polyclonal antibody against NFKB1 (Ab-907). Recognizes NFKB1 (Ab-907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB1 (Ab-907) Antibody

CSB-PA696291-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB1 (Ab-907). Recognizes NFKB1 (Ab-907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

NFKB2 (Ab-866) Antibody

CSB-PA000249- each
EUR 402
Description: A polyclonal antibody against NFKB2 (Ab-866). Recognizes NFKB2 (Ab-866) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

NFKB2 (Ab-866) Antibody

CSB-PA000249-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against NFKB2 (Ab-866). Recognizes NFKB2 (Ab-866) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Antibody for Human NFKB1

SPC-1303D 0.1ml
EUR 376.8
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is unconjugated.

Antibody for Human NFKB1

SPC-1303D-A390 0.1ml
EUR 433.2
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 390.

Antibody for Human NFKB1

SPC-1303D-A488 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 488.

Antibody for Human NFKB1

SPC-1303D-A565 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 565.

Antibody for Human NFKB1

SPC-1303D-A594 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 594.

Antibody for Human NFKB1

SPC-1303D-A633 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 633.

Antibody for Human NFKB1

SPC-1303D-A655 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 655.

Antibody for Human NFKB1

SPC-1303D-A680 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 680.

Antibody for Human NFKB1

SPC-1303D-A700 0.1ml
EUR 432
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 700.

Antibody for Human NFKB1

SPC-1303D-ALP 0.1ml
EUR 426
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human NFKB1

SPC-1303D-APC 0.1ml
EUR 430.8
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to APC .

Antibody for Human NFKB1

SPC-1303D-APCCY7 0.1ml
EUR 518.4
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to APC/Cy7.

Antibody for Human NFKB1

SPC-1303D-BI 0.1ml
EUR 428.4
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Biotin.

Antibody for Human NFKB1

SPC-1303D-DY350 0.1ml
EUR 523.2
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 350.

Antibody for Human NFKB1

SPC-1303D-DY405 0.1ml
EUR 494.4
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 405.

Antibody for Human NFKB1

SPC-1303D-DY488 0.1ml
EUR 471.6
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 488.

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