Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : c-Met(also named as MET or HGFR) is a receptor tyrosine kinase that transduces signals from the extracell µLar matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. c-Met reg µLates many physiological processes including proliferation, scattering, morphogenesis and survival. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are dis µLfide linked to form the mature receptor. Overexpression and/or mutation of c-Met has been reported in various human malignancies, including lung cancer, breast cancer, head and neck cancer, gastric cancer, colorectal cancer, bladder cancer, uterine cervix carcinoma, and esophageal carcinoma, c-Met co µLd serve as an important therapeutic target(PMID : 26036285). This antibody recognizes the N-term of c-Met.
Immunogen : met proto-oncogene(hepatocyte growth factor receptor)
Aliases : AUTS9, c-Met, HGF receptor, HGF/SF receptor, HGFR, MET, Proto oncogene c Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine protein kinase Met
Observed MW : 150 kDa
Uniprot ID : P08581
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 1000; IHC : 1 : 50-1 : 200
Gene ID : 4233
Research Area : Epigenetics, Metabolism, Immunology, Cancer, Neuroscience, Stem Cells, Cell Division and Proliferation