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IgG Lambda Light Chain antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : immunoglob µLin lambda locus
Aliases : IgG Lambda Light Chain, IGL, IGL-, immunoglob µLin lambda locus
Observed MW : 25 kDa
Uniprot ID : P0DOX8
Reactivity : Human
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID :
Research Area :
0,01 0.01 USD
IgG kappa Light Chain antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : immunoglob µLin kappa locus
Aliases : IgG Kappa Light Chain, IGK, IGK-, IGKC, immunoglob µLin kappa locus
Observed MW : 26 kDa
Uniprot ID : P0DOX7
Reactivity : Human
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID :
Research Area :
0,01 0.01 USD
IgG control antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : Recombinant Protein
Aliases : Human IgG
Observed MW : 25 kda, 50 kDa
Uniprot ID :
Reactivity : Human
Application : ELISA, WB
Recommended dilution : WB : 1 : 2000-1 : 20000
Gene ID :
Research Area : Immunology
0,01 0.01 USD
IgG Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : IgG
Product Type : polyclonal Ab Antibody
Immunogen Species : Goat
UniProt ID :
Immunogen : Goat IgG light chain (Native Protein)
Raised in : Guinea pig
Species Reactivity : Goat
Tested Applications : ELISA
Background : The basic structure of IgG molec µLe is composed of four polypeptide chains, that is, from the same two small molec µLar weight peptides (referred to as light chain, Light chain, L chain, the relative molec µLar mass of about 25,000) and two the same relative molec µLar mass of the larger peptides (called heavy chain, heavy chain, H chain, the relative molec µLar mass of about 55,000) composed. A natural two light chains of IgG molec µLes are always the same. The goat IgG antibodies can specifically recognize the light chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others
0,01 0.01 USD
IgG Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : IgG
Product Type : polyclonal Ab Antibody
Immunogen Species : Goat
UniProt ID :
Immunogen : Goat IgG light chain (Native Protein)
Raised in : Guinea pig
Species Reactivity : Goat
Tested Applications :
Background : The basic structure of IgG molec µLe is composed of four polypeptide chains, that is, from the same two small molec µLar weight peptides (referred to as light chain, Light chain, L chain, the relative molec µLar mass of about 25,000) and two the same relative molec µLar mass of the larger peptides (called heavy chain, heavy chain, H chain, the relative molec µLar mass of about 55,000) composed. A natural two light chains of IgG molec µLes are always the same. The goat IgG antibodies can specifically recognize the light chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others
0,01 0.01 USD
IgG Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : IgG
Product Type : polyclonal Ab Antibody
Immunogen Species : Goat
UniProt ID :
Immunogen : Goat IgG light chain (Native Protein)
Raised in : Guinea pig
Species Reactivity : Goat
Tested Applications : ELISA
Background : The basic structure of IgG molec µLe is composed of four polypeptide chains, that is, from the same two small molec µLar weight peptides (referred to as light chain, Light chain, L chain, the relative molec µLar mass of about 25,000) and two the same relative molec µLar mass of the larger peptides (called heavy chain, heavy chain, H chain, the relative molec µLar mass of about 55,000) composed. A natural two light chains of IgG molec µLes are always the same. The goat IgG antibodies can specifically recognize the light chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others
0,01 0.01 USD
IgG Antibody
Volume : 50 µg
Clone Number :
Aliases : IgG
Product Type : polyclonal Ab Antibody
Immunogen Species : Goat
UniProt ID :
Immunogen : Goat IgG light chain (Native Protein)
Raised in : Guinea pig
Species Reactivity : Goat
Tested Applications : ELISA
Background : The basic structure of IgG molec µLe is composed of four polypeptide chains, that is, from the same two small molec µLar weight peptides (referred to as light chain, Light chain, L chain, the relative molec µLar mass of about 25,000) and two the same relative molec µLar mass of the larger peptides (called heavy chain, heavy chain, H chain, the relative molec µLar mass of about 55,000) composed. A natural two light chains of IgG molec µLes are always the same. The goat IgG antibodies can specifically recognize the light chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others
0,01 0.01 USD
IgG (Light Chain Specific) Monoclonal Antibody
Volume : 50 µg
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Rabbit
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Rabbit
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background :
Clonality : Monoclonal
Isotype : IgG
Purification Method : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conj µgate : Non-conj µgated
Buffer : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IgG (Light Chain Specific)
Research Areas : Others
0,01 0.01 USD
IgG (H+L) Monoclonal Antibody
Volume : 50 µg
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Rabbit
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Rabbit
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background :
Clonality : Monoclonal
Isotype : IgG
Purification Method : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conj µgate : Non-conj µgated
Buffer : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IgG (H+L)
Research Areas : Others
0,01 0.01 USD
IgG (Fc specific Heavy Chain) Monoclonal Antibody
Volume : 50 µg
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Rabbit
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Rabbit
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background :
Clonality : Monoclonal
Isotype : IgG
Purification Method : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conj µgate : Non-conj µgated
Buffer : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IgG (Fc specific,Heavy Chain)
Research Areas : Others
0,01 0.01 USD
IGFN1 Antibody
Volume : 50 µg
Clone Number :
Aliases : IGFN1 antibody; EEF1A2BP1 antibody; KYIP1Immunoglob µLin-like and fibronectin type III domain-containing protein 1 antibody; EEF1A2-binding protein 1 antibody; KY-interacting protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86VF2
Immunogen : Recombinant Protein
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC; WB : 1 : 2000-5000, IHC : 1 : 200-500
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Affinity purification
Conj µgate : Non-conj µgated
Buffer : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFN1
Research Areas : Epigenetics and Nuclear Signaling
0,01 0.01 USD
IGFL4 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFL4
GeneID : 444882
Uniprot : Q6B9Z1
Specificity : IGFL4 Antibody detects endogenous levels of total IGFL4.
Immunogen : A syntheVolumed peptide derived from human IGFL4, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2840691
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF10111-BP
Des# Blocking Peptide : IGFL4 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFL3 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFL3
GeneID : 388555
Uniprot : Q6UXB1
Specificity : IGFL3 Antibody detects endogenous levels of total IGFL3.
Immunogen : A syntheVolumed peptide derived from human IGFL3, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842173
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8977-BP
Des# Blocking Peptide : IGFL3 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFL2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFL2
GeneID : 147920
Uniprot : Q6UWQ7
Specificity : IGFL2 Antibody detects endogenous levels of total IGFL2.
Immunogen : A syntheVolumed peptide derived from human IGFL2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2840690
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF10110-BP
Des# Blocking Peptide : IGFL2 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFL1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFL1
GeneID : 374918
Uniprot : Q6UW32
Specificity : IGFL1 Antibody detects endogenous levels of total IGFL1.
Immunogen : A syntheVolumed peptide derived from human IGFL1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human,Mouse
Prediction : Bovine,Sheep
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839723
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2517-BP
Des# Blocking Peptide : IGFL1 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBPL1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBPL1
GeneID : 347252
Uniprot : Q8WX77
Specificity : IGFBPL1 Antibody detects endogenous levels of total IGFBPL1.
Immunogen : A syntheVolumed peptide derived from human IGFBPL1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human,Mouse,Rat
Prediction : Bovine,Sheep,Rabbit
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839718
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2512-BP
Des# Blocking Peptide : IGFBPL1 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP7 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : AGM antibody; Angiomod µLin antibody; FSTL2 antibody; IBP-7 antibody; IBP7 antibody; IBP7_HUMAN antibody; IGF binding protein 7 antibody; IGF-binding protein 7 antibody; IGFBP rP1 antibody; IGFBP-7 antibody; IGFBP-rP1 antibody; IGFBP7 antibody; IGFBPRP1 antibody; Ins µLin like growth factor binding protein 7 antibody; Ins µLin-like growth factor-binding protein 7 antibody; MAC25 antibody; MAC25 protein antibody; PGI2 stim µLating factor antibody; PGI2-stim µLating factor antibody; Prostacyclin stim µLating factor antibody; Prostacyclin-stim µLating factor antibody; PSF antibody; RAMSVPS antibody; TAF antibody; Tumor-derived adhesion factor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16270
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 7 protein (64-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds IGF-I and IGF-II with a relatively low affinity. Stim µLates prostacyclin (PGI2) production. Stim µLates cell adhesion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP7
Research Areas : Cancer; Signal transduction
0,01 0.01 USD
IGFBP7 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : AGM antibody; Angiomod µLin antibody; FSTL2 antibody; IBP-7 antibody; IBP7 antibody; IBP7_HUMAN antibody; IGF binding protein 7 antibody; IGF-binding protein 7 antibody; IGFBP rP1 antibody; IGFBP-7 antibody; IGFBP-rP1 antibody; IGFBP7 antibody; IGFBPRP1 antibody; Ins µLin like growth factor binding protein 7 antibody; Ins µLin-like growth factor-binding protein 7 antibody; MAC25 antibody; MAC25 protein antibody; PGI2 stim µLating factor antibody; PGI2-stim µLating factor antibody; Prostacyclin stim µLating factor antibody; Prostacyclin-stim µLating factor antibody; PSF antibody; RAMSVPS antibody; TAF antibody; Tumor-derived adhesion factor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16270
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 7 protein (64-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds IGF-I and IGF-II with a relatively low affinity. Stim µLates prostacyclin (PGI2) production. Stim µLates cell adhesion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP7
Research Areas : Cancer; Signal transduction
0,01 0.01 USD
IGFBP7 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AGM antibody; Angiomod µLin antibody; FSTL2 antibody; IBP-7 antibody; IBP7 antibody; IBP7_HUMAN antibody; IGF binding protein 7 antibody; IGF-binding protein 7 antibody; IGFBP rP1 antibody; IGFBP-7 antibody; IGFBP-rP1 antibody; IGFBP7 antibody; IGFBPRP1 antibody; Ins µLin like growth factor binding protein 7 antibody; Ins µLin-like growth factor-binding protein 7 antibody; MAC25 antibody; MAC25 protein antibody; PGI2 stim µLating factor antibody; PGI2-stim µLating factor antibody; Prostacyclin stim µLating factor antibody; Prostacyclin-stim µLating factor antibody; PSF antibody; RAMSVPS antibody; TAF antibody; Tumor-derived adhesion factor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16270
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 7 protein (64-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds IGF-I and IGF-II with a relatively low affinity. Stim µLates prostacyclin (PGI2) production. Stim µLates cell adhesion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP7
Research Areas : Cancer; Signal transduction
0,01 0.01 USD
IGFBP7 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBP7
GeneID : 3490
Uniprot : Q16270
Specificity : IGFBP7 Antibody detects endogenous levels of total IGFBP7.
Immunogen : A syntheVolumed peptide derived from human IGFBP7, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Bovine,Sheep,Rabbit,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 100, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839085
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7131-BP
Des# Blocking Peptide : IGFBP7 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP6 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : IBP 6 antibody; IBP-6 antibody; IBP6 antibody; IBP6_HUMAN antibody; IGF binding protein 6 antibody; IGF-binding protein 6 antibody; IGFBP 6 antibody; IGFBP-6 antibody; IGFBP6 antibody; Ins µLin like growth factor binding protein 6 antibody; Ins µLin-like growth factor-binding protein 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24592
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 6 protein (32-161AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stim µLate the growth promoting effects of the IGFs on cell c µLture. They alter the interaction of IGFs with their cell surface receptors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP6
Research Areas : Signal transduction
0,01 0.01 USD
IGFBP6 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : IBP 6 antibody; IBP-6 antibody; IBP6 antibody; IBP6_HUMAN antibody; IGF binding protein 6 antibody; IGF-binding protein 6 antibody; IGFBP 6 antibody; IGFBP-6 antibody; IGFBP6 antibody; Ins µLin like growth factor binding protein 6 antibody; Ins µLin-like growth factor-binding protein 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24592
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 6 protein (32-161AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stim µLate the growth promoting effects of the IGFs on cell c µLture. They alter the interaction of IGFs with their cell surface receptors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP6
Research Areas : Signal transduction
0,01 0.01 USD
IGFBP6 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : IBP 6 antibody; IBP-6 antibody; IBP6 antibody; IBP6_HUMAN antibody; IGF binding protein 6 antibody; IGF-binding protein 6 antibody; IGFBP 6 antibody; IGFBP-6 antibody; IGFBP6 antibody; Ins µLin like growth factor binding protein 6 antibody; Ins µLin-like growth factor-binding protein 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24592
Immunogen : Recombinant Human Ins µLin-like growth factor-binding protein 6 protein (32-161AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stim µLate the growth promoting effects of the IGFs on cell c µLture. They alter the interaction of IGFs with their cell surface receptors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP6
Research Areas : Signal transduction
0,01 0.01 USD
IGFBP6 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBP6
GeneID : 3489
Uniprot : P24592
Specificity : IGFBP6 Antibody detects endogenous levels of total IGFBP6.
Immunogen : A syntheVolumed peptide derived from human IGFBP6, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842155
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8959-BP
Des# Blocking Peptide : IGFBP6 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP5 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBP5
GeneID : 3488
Uniprot : P24593
Specificity : IGFBP5 Antibody detects endogenous levels of total IGFBP5.
Immunogen : A syntheVolumed peptide derived from human IGFBP5, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838536
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6574-BP
Des# Blocking Peptide : IGFBP5 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP4 antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : This gene is a member of the ins µLin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglob µLin type-I domain. The protein binds both ins µLin-like growth factors (IGFs) I and II and circ µLates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Immunogen : ins µLin-like growth factor binding protein 4
Aliases : IBP4
Observed MW : 17 kDa
Uniprot ID : P22692
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 100
Gene ID : 3487
Research Area : Cardiovasc µLar, Metabolism, Signal Transduction
0,01 0.01 USD
IGFBP3 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBP3
GeneID : 3486
Uniprot : P17936
Specificity : IGFBP3 Antibody detects endogenous levels of total IGFBP3.
Immunogen : A syntheVolumed peptide derived from human IGFBP3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Horse,Sheep,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835084
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF6203-BP
Des# Blocking Peptide : IGFBP3 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBP2
GeneID : 3485
Uniprot : P18065
Specificity : IGFBP2 Antibody detects endogenous levels of total IGFBP2.
Immunogen : A syntheVolumed peptide derived from human IGFBP2, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841231
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7765-BP
Des# Blocking Peptide : IGFBP2 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP1 Monoclonal Antibody
Volume : 50 µg
Clone Number : 1E1B2
Aliases : IGFBP1Ins µLin-like growth factor-binding protein 1IGF-binding protein 1
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P08833
Immunogen : Recombinant Human IGFBP1 Protein
Raised in : Mouse
Species Reactivity : Human,Mouse
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background : This gene is a member of the Ins µLin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglob µLin domain. The protein binds both ins µLin-like growth factors (IGFs) I and II and circ µLates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : >95%,Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 15mmol/L NaN3
Constituents : 0.1mol/L Nacl
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGFBP1
Research Areas : Cardiovasc µLar;Signal transduction
0,01 0.01 USD
Igfbp1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Igfbp1 antibody; Igfbp-1 antibody; Ins µLin-like growth factor-binding protein 1 antibody; IBP-1 antibody; IGF-binding protein 1 antibody; IGFBP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P47876
Immunogen : Recombinant Mouse Ins µLin-like growth factor-binding protein 1 protein (26-272AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stim µLate the growth promoting effects of the IGFs on cell c µLture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Igfbp1
Research Areas : Cardiovasc µLar; Signal transduction
0,01 0.01 USD
Igfbp1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Igfbp1 antibody; Igfbp-1 antibody; Ins µLin-like growth factor-binding protein 1 antibody; IBP-1 antibody; IGF-binding protein 1 antibody; IGFBP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P47876
Immunogen : Recombinant Mouse Ins µLin-like growth factor-binding protein 1 protein (26-272AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stim µLate the growth promoting effects of the IGFs on cell c µLture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Igfbp1
Research Areas : Cardiovasc µLar; Signal transduction
0,01 0.01 USD
Igfbp1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Igfbp1 antibody; Igfbp-1 antibody; Ins µLin-like growth factor-binding protein 1 antibody; IBP-1 antibody; IGF-binding protein 1 antibody; IGFBP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P47876
Immunogen : Recombinant Mouse Ins µLin-like growth factor-binding protein 1 protein (26-272AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stim µLate the growth promoting effects of the IGFs on cell c µLture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Igfbp1
Research Areas : Cardiovasc µLar; Signal transduction
0,01 0.01 USD
IGFBP1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFBP1
GeneID : 3484
Uniprot : P08833
Specificity : IGFBP1 Antibody detects endogenous levels of total IGFBP1.
Immunogen : A syntheVolumed peptide derived from human IGFBP1 corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Horse,Rabbit,Dog,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 100, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839084
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7130-BP
Des# Blocking Peptide : IGFBP1 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGFBP1
Volume : 50 µg
Protein Type : Cytokine
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGFBP 4
Volume : 50 µg
Protein Type : Cytokine
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGFALS Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGFALS
GeneID : 3483
Uniprot : P35858
Specificity : IGFALS Antibody detects endogenous levels of total IGFALS.
Immunogen : A syntheVolumed peptide derived from human IGFALS, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837001
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF4650-BP
Des# Blocking Peptide : IGFALS Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF2R Specific antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : ins µLin-like growth factor 2 receptor
Aliases :
Observed MW : 274 kDa
Uniprot ID : P11717
Reactivity : Human
Application : ELISA, WB, IHC, IP, IF
Recommended dilution : WB : 1 : 1000-1 : 4000; IP : 1 : 500-1 : 1000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID :
Research Area : Cancer, Immunology, Signal Transduction
0,01 0.01 USD
IGF2R Antibody HRP conjugated
Volume : 50 µL
Clone Number :
Aliases : 300 kDa mannose 6 phosphate receptor antibody; 300 kDa mannose 6-phosphate receptor antibody; Cation independent mannose 6 phosphate receptor antibody; Cation-independent mannose-6-phosphate receptor antibody; CD222 antibody; CD222 antigen antibody; CI Man 6 P receptor antibody; CI Man-6-P receptor antibody; CI MPR antibody; CI-M6PR antibody; CI-MPR antibody; CIMPR antibody; IGF 2 receptor antibody; IGF 2R antibody; IGF II receptor antibody; IGF-II receptor antibody; IGF2 receptor antibody; Igf2r antibody; Ins µLin like growth factor 2 receptor antibody; Ins µLin like growth factor II receptor antibody; Ins µLin-like growth factor 2 receptor antibody; Ins µLin-like growth factor II receptor antibody; M6P R antibody; M6P/IGF2 receptor antibody; M6P/IGF2R antibody; M6PR antibody; mannose 6 phosphate receptor antibody; mannose 6 phosphate receptor, cation independent antibody; MPR 300 antibody; MPR300 antibody; MPRI antibody; MPRI_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11717
Immunogen : Recombinant Human Cation-independent mannose-6-phosphate receptor protein (2328-2491AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the res µLting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive reg µLator of T-cell coactivation, by binding DPP4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2R
Research Areas : Tags & Cell Markers; Immunology; Signal transduction
0,01 0.01 USD
IGF2R Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : 300 kDa mannose 6 phosphate receptor antibody; 300 kDa mannose 6-phosphate receptor antibody; Cation independent mannose 6 phosphate receptor antibody; Cation-independent mannose-6-phosphate receptor antibody; CD222 antibody; CD222 antigen antibody; CI Man 6 P receptor antibody; CI Man-6-P receptor antibody; CI MPR antibody; CI-M6PR antibody; CI-MPR antibody; CIMPR antibody; IGF 2 receptor antibody; IGF 2R antibody; IGF II receptor antibody; IGF-II receptor antibody; IGF2 receptor antibody; Igf2r antibody; Ins µLin like growth factor 2 receptor antibody; Ins µLin like growth factor II receptor antibody; Ins µLin-like growth factor 2 receptor antibody; Ins µLin-like growth factor II receptor antibody; M6P R antibody; M6P/IGF2 receptor antibody; M6P/IGF2R antibody; M6PR antibody; mannose 6 phosphate receptor antibody; mannose 6 phosphate receptor, cation independent antibody; MPR 300 antibody; MPR300 antibody; MPRI antibody; MPRI_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11717
Immunogen : Recombinant Human Cation-independent mannose-6-phosphate receptor protein (2328-2491AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the res µLting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive reg µLator of T-cell coactivation, by binding DPP4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2R
Research Areas : Tags & Cell Markers; Immunology; Signal transduction
0,01 0.01 USD
IGF2R Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : 300 kDa mannose 6 phosphate receptor antibody; 300 kDa mannose 6-phosphate receptor antibody; Cation independent mannose 6 phosphate receptor antibody; Cation-independent mannose-6-phosphate receptor antibody; CD222 antibody; CD222 antigen antibody; CI Man 6 P receptor antibody; CI Man-6-P receptor antibody; CI MPR antibody; CI-M6PR antibody; CI-MPR antibody; CIMPR antibody; IGF 2 receptor antibody; IGF 2R antibody; IGF II receptor antibody; IGF-II receptor antibody; IGF2 receptor antibody; Igf2r antibody; Ins µLin like growth factor 2 receptor antibody; Ins µLin like growth factor II receptor antibody; Ins µLin-like growth factor 2 receptor antibody; Ins µLin-like growth factor II receptor antibody; M6P R antibody; M6P/IGF2 receptor antibody; M6P/IGF2R antibody; M6PR antibody; mannose 6 phosphate receptor antibody; mannose 6 phosphate receptor, cation independent antibody; MPR 300 antibody; MPR300 antibody; MPRI antibody; MPRI_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11717
Immunogen : Recombinant Human Cation-independent mannose-6-phosphate receptor protein (2328-2491AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the res µLting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive reg µLator of T-cell coactivation, by binding DPP4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2R
Research Areas : Tags & Cell Markers; Immunology; Signal transduction
0,01 0.01 USD
IGF2R Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF2R
GeneID : 3482
Uniprot : P11717
Specificity : IGF2R Antibody detects endogenous levels of total IGF2R.
Immunogen : A syntheVolumed peptide derived from human IGF2R.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2847729
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF6939-BP
Des# Blocking Peptide : IGF2R Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF2BP3 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Cancer/testis antigen 98 antibody; CT98 antibody; DKFZp686F1078 antibody; hKOC antibody; IF2B3_HUMAN antibody; IGF II mRNA binding protein 3 antibody; IGF-II mRNA-binding protein 3 antibody; IGF2 mRNA binding protein 3 antibody; IGF2 mRNA-binding protein 3 antibody; IGF2BP3 antibody; IMP 3 antibody; IMP-3 antibody; Ins µLin like growth factor 2 mRNA binding protein 3 antibody; Ins µLin-like growth factor 2 mRNA-binding protein 3 antibody; KH domain containing protein overexpressed in cancer antibody; KH domain-containing protein overexpressed in cancer antibody; KOC 1 antibody; KOC1 antibody; VICKZ 3 antibody; VICKZ family member 3 antibody; VICKZ3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00425
Immunogen : Recombinant Human Ins µLin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also mod µLates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\'-UTR of the ins µLin-like growth factor 2 (IGF2) mRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2BP3
Research Areas : Epigenetics and Nuclear Signaling; Cancer
0,01 0.01 USD
IGF2BP3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cancer/testis antigen 98 antibody; CT98 antibody; DKFZp686F1078 antibody; hKOC antibody; IF2B3_HUMAN antibody; IGF II mRNA binding protein 3 antibody; IGF-II mRNA-binding protein 3 antibody; IGF2 mRNA binding protein 3 antibody; IGF2 mRNA-binding protein 3 antibody; IGF2BP3 antibody; IMP 3 antibody; IMP-3 antibody; Ins µLin like growth factor 2 mRNA binding protein 3 antibody; Ins µLin-like growth factor 2 mRNA-binding protein 3 antibody; KH domain containing protein overexpressed in cancer antibody; KH domain-containing protein overexpressed in cancer antibody; KOC 1 antibody; KOC1 antibody; VICKZ 3 antibody; VICKZ family member 3 antibody; VICKZ3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00425
Immunogen : Recombinant Human Ins µLin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also mod µLates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\'-UTR of the ins µLin-like growth factor 2 (IGF2) mRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2BP3
Research Areas : Epigenetics and Nuclear Signaling; Cancer
0,01 0.01 USD
IGF2BP3 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Cancer/testis antigen 98 antibody; CT98 antibody; DKFZp686F1078 antibody; hKOC antibody; IF2B3_HUMAN antibody; IGF II mRNA binding protein 3 antibody; IGF-II mRNA-binding protein 3 antibody; IGF2 mRNA binding protein 3 antibody; IGF2 mRNA-binding protein 3 antibody; IGF2BP3 antibody; IMP 3 antibody; IMP-3 antibody; Ins µLin like growth factor 2 mRNA binding protein 3 antibody; Ins µLin-like growth factor 2 mRNA-binding protein 3 antibody; KH domain containing protein overexpressed in cancer antibody; KH domain-containing protein overexpressed in cancer antibody; KOC 1 antibody; KOC1 antibody; VICKZ 3 antibody; VICKZ family member 3 antibody; VICKZ3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00425
Immunogen : Recombinant Human Ins µLin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also mod µLates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\'-UTR of the ins µLin-like growth factor 2 (IGF2) mRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2BP3
Research Areas : Epigenetics and Nuclear Signaling; Cancer
0,01 0.01 USD
IGF2BP3 Antibody
Volume : 100 µL
Host : Mouse
Clonality : Monoclonal
Isotype : IgG1
GeneName : IGF2BP3
GeneID : 10643
Uniprot : O00425
Specificity : IGF2BP3 antibody detects endogenous levels of total IGF2BP3.
Immunogen : Purified recombinant fragment of human IGF2BP3 expressed in E. Coli.
Storage : Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IHC,ELISA
Dilution : ELISA 1 : 10000, WB 1 : 500-1 : 2000, IHC 1 : 200-1 : 1000
Conj µgate : Unconj µgated
RRID : AB_2833861
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide :
Des# Blocking Peptide :
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF2BP2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF2BP2
GeneID : 10644
Uniprot : Q9Y6M1
Specificity : IGF2BP2 Antibody detects endogenous levels of total IGF2BP2.
Immunogen : A syntheVolumed peptide derived from human IGF2BP2, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837061
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF4710-BP
Des# Blocking Peptide : IGF2BP2 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF2BP1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Coding region determinant-binding protein antibody; CRD BP antibody; CRD-BP antibody; CRDBP antibody; IF2B1 antibody; IF2B1_HUMAN antibody; IGF II mRNA binding protein 1 antibody; IGF-II mRNA-binding protein 1 antibody; IGF2 mRNA binding protein 1 antibody; IGF2 mRNA-binding protein 1 antibody; IGF2BP1 antibody; IMP 1 antibody; IMP-1 antibody; IMP1 antibody; Ins µLin like growth factor 2 mRNA binding protein 1 antibody; Ins µLin-like growth factor 2 mRNA-binding protein 1 antibody; VICKZ family member 1 antibody; VICKZ1 antibody; ZBP 1 antibody; ZBP-1 antibody; ZBP1 antibody; Zip code binding protein 1 antibody; Zip code-binding protein 1 antibody; Zipcode binding protein 1 antibody; Zipcode-binding protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZI8
Immunogen : Recombinant Human Ins µLin-like growth factor 2 mRNA-binding protein 1 protein (440-534AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also mod µLates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in ad µLt sensory neurons (By similarity). Reg µLates localized beta-actin/ACTB mRNA translation, a crucial process for cell polarity, cell migration and neurite outgrowth. Co-transcriptionally associates with the ACTB mRNA in the nucleus. This binding involves a conserved 54-nucleotide element in the ACTB mRNA 3\'-UTR, known as the \'zipcode\'. The RNP thus formed is exported to the cytoplasm, binds to a motor protein and is transported along the cytoskeleton to the cell periphery. During transport, prevents ACTB mRNA from being translated into protein. When the RNP complex reaches its destination near the plasma membrane, IGF2BP1 is phosphorylated. This releases the mRNA, allowing ribosomal 40S and 60S subunits to assemble and initiate ACTB protein synthesis. Monomeric ACTB then assembles into the subcortical actin cytoskeleton (By similarity). During neuronal development, key reg µLator of neurite outgrowth, growth cone guidance and neuronal cell migration, presumably thro µgh the spatiotemporal fine tuning of protein synthesis, such as that of ACTB (By similarity). May reg µLate mRNA transport to activated synapses (By similarity). Binds to and stabilizes ABCB1/MDR-1 mRNA (By similarity). During interstinal wound repair, interacts with and stabilizes PTGS2 transcript. PTGS2 mRNA stabilization may be crucial for colonic mucosal wound healing (By similarity). Binds to the 3\'-UTR of IGF2 mRNA by a mechanism of cooperative and sequential dimerization and reg µLates IGF2 mRNA subcell µLar localization and translation. Binds to MYC mRNA, in the coding region instability determinant (CRD) of the open reading frame (ORF), hence prevents MYC cleavage by endonucleases and possibly microRNA targeting to MYC-CRD. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to the oncofetal H19 transcript and to the neuron-specific TAU mRNA and reg µLates their localizations. Binds to and stabilizes BTRC/FBW1A mRNA. Binds to the adenine-rich autoreg µLatory sequence (ARS) located in PABPC1 mRNA and represses its translation. PABPC1 mRNA-binding is stim µLated by PABPC1 protein. Prevents BTRC/FBW1A mRNA degradation by disrupting microRNA-dependent interaction with AGO2. Promotes the directed movement of tumor-derived cells by fine-tuning intracell µLar signaling networks. Binds to MAPK4 3\'-UTR and inhibits its translation. Interacts with PTEN transcript open reading frame (ORF) and prevents mRNA decay. This combined action on MAPK4 (down-reg µLation) and PTEN (up-reg µLation) antagonizes HSPB1 phosphorylation, consequently it prevents G-actin sequestration by phosphorylated HSPB1 allowing F-actin polymerization. Hence enhances the velocity of cell migration and stim µLates directed cell migration by PTEN-mod µLated polarization. Interacts with Hepatitis C virus (HCV) 5\'-UTR and 3\'-UTR and specifically enhances translation at the HCV IRES, but not 5\'-cap-dependent translation, possibly by recruiting eIF3. Interacts with HIV-1 GAG protein and blocks the formation of infectious HIV-1 particles. Reduces HIV-1 assembly by inhibiting viral RNA packaging, as well as assembly and processing of GAG protein on cell µLar membranes. During cell µLar stress, such as oxidative stress or heat shock, stabilizes target mRNAs that are recruited to stress gran µLes, including CD44, IGF2, MAPK4, MYC, PTEN, RAPGEF2 and RPS6KA5 transcripts.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2BP1
Research Areas : Epigenetics and Nuclear Signaling
0,01 0.01 USD
IGF2BP1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Coding region determinant-binding protein antibody; CRD BP antibody; CRD-BP antibody; CRDBP antibody; IF2B1 antibody; IF2B1_HUMAN antibody; IGF II mRNA binding protein 1 antibody; IGF-II mRNA-binding protein 1 antibody; IGF2 mRNA binding protein 1 antibody; IGF2 mRNA-binding protein 1 antibody; IGF2BP1 antibody; IMP 1 antibody; IMP-1 antibody; IMP1 antibody; Ins µLin like growth factor 2 mRNA binding protein 1 antibody; Ins µLin-like growth factor 2 mRNA-binding protein 1 antibody; VICKZ family member 1 antibody; VICKZ1 antibody; ZBP 1 antibody; ZBP-1 antibody; ZBP1 antibody; Zip code binding protein 1 antibody; Zip code-binding protein 1 antibody; Zipcode binding protein 1 antibody; Zipcode-binding protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZI8
Immunogen : Recombinant Human Ins µLin-like growth factor 2 mRNA-binding protein 1 protein (440-534AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also mod µLates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in ad µLt sensory neurons (By similarity). Reg µLates localized beta-actin/ACTB mRNA translation, a crucial process for cell polarity, cell migration and neurite outgrowth. Co-transcriptionally associates with the ACTB mRNA in the nucleus. This binding involves a conserved 54-nucleotide element in the ACTB mRNA 3\'-UTR, known as the \'zipcode\'. The RNP thus formed is exported to the cytoplasm, binds to a motor protein and is transported along the cytoskeleton to the cell periphery. During transport, prevents ACTB mRNA from being translated into protein. When the RNP complex reaches its destination near the plasma membrane, IGF2BP1 is phosphorylated. This releases the mRNA, allowing ribosomal 40S and 60S subunits to assemble and initiate ACTB protein synthesis. Monomeric ACTB then assembles into the subcortical actin cytoskeleton (By similarity). During neuronal development, key reg µLator of neurite outgrowth, growth cone guidance and neuronal cell migration, presumably thro µgh the spatiotemporal fine tuning of protein synthesis, such as that of ACTB (By similarity). May reg µLate mRNA transport to activated synapses (By similarity). Binds to and stabilizes ABCB1/MDR-1 mRNA (By similarity). During interstinal wound repair, interacts with and stabilizes PTGS2 transcript. PTGS2 mRNA stabilization may be crucial for colonic mucosal wound healing (By similarity). Binds to the 3\'-UTR of IGF2 mRNA by a mechanism of cooperative and sequential dimerization and reg µLates IGF2 mRNA subcell µLar localization and translation. Binds to MYC mRNA, in the coding region instability determinant (CRD) of the open reading frame (ORF), hence prevents MYC cleavage by endonucleases and possibly microRNA targeting to MYC-CRD. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to the oncofetal H19 transcript and to the neuron-specific TAU mRNA and reg µLates their localizations. Binds to and stabilizes BTRC/FBW1A mRNA. Binds to the adenine-rich autoreg µLatory sequence (ARS) located in PABPC1 mRNA and represses its translation. PABPC1 mRNA-binding is stim µLated by PABPC1 protein. Prevents BTRC/FBW1A mRNA degradation by disrupting microRNA-dependent interaction with AGO2. Promotes the directed movement of tumor-derived cells by fine-tuning intracell µLar signaling networks. Binds to MAPK4 3\'-UTR and inhibits its translation. Interacts with PTEN transcript open reading frame (ORF) and prevents mRNA decay. This combined action on MAPK4 (down-reg µLation) and PTEN (up-reg µLation) antagonizes HSPB1 phosphorylation, consequently it prevents G-actin sequestration by phosphorylated HSPB1 allowing F-actin polymerization. Hence enhances the velocity of cell migration and stim µLates directed cell migration by PTEN-mod µLated polarization. Interacts with Hepatitis C virus (HCV) 5\'-UTR and 3\'-UTR and specifically enhances translation at the HCV IRES, but not 5\'-cap-dependent translation, possibly by recruiting eIF3. Interacts with HIV-1 GAG protein and blocks the formation of infectious HIV-1 particles. Reduces HIV-1 assembly by inhibiting viral RNA packaging, as well as assembly and processing of GAG protein on cell µLar membranes. During cell µLar stress, such as oxidative stress or heat shock, stabilizes target mRNAs that are recruited to stress gran µLes, including CD44, IGF2, MAPK4, MYC, PTEN, RAPGEF2 and RPS6KA5 transcripts.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2BP1
Research Areas : Epigenetics and Nuclear Signaling
0,01 0.01 USD
IGF2BP1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Coding region determinant-binding protein antibody; CRD BP antibody; CRD-BP antibody; CRDBP antibody; IF2B1 antibody; IF2B1_HUMAN antibody; IGF II mRNA binding protein 1 antibody; IGF-II mRNA-binding protein 1 antibody; IGF2 mRNA binding protein 1 antibody; IGF2 mRNA-binding protein 1 antibody; IGF2BP1 antibody; IMP 1 antibody; IMP-1 antibody; IMP1 antibody; Ins µLin like growth factor 2 mRNA binding protein 1 antibody; Ins µLin-like growth factor 2 mRNA-binding protein 1 antibody; VICKZ family member 1 antibody; VICKZ1 antibody; ZBP 1 antibody; ZBP-1 antibody; ZBP1 antibody; Zip code binding protein 1 antibody; Zip code-binding protein 1 antibody; Zipcode binding protein 1 antibody; Zipcode-binding protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZI8
Immunogen : Recombinant Human Ins µLin-like growth factor 2 mRNA-binding protein 1 protein (440-534AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also mod µLates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in ad µLt sensory neurons (By similarity). Reg µLates localized beta-actin/ACTB mRNA translation, a crucial process for cell polarity, cell migration and neurite outgrowth. Co-transcriptionally associates with the ACTB mRNA in the nucleus. This binding involves a conserved 54-nucleotide element in the ACTB mRNA 3\'-UTR, known as the \'zipcode\'. The RNP thus formed is exported to the cytoplasm, binds to a motor protein and is transported along the cytoskeleton to the cell periphery. During transport, prevents ACTB mRNA from being translated into protein. When the RNP complex reaches its destination near the plasma membrane, IGF2BP1 is phosphorylated. This releases the mRNA, allowing ribosomal 40S and 60S subunits to assemble and initiate ACTB protein synthesis. Monomeric ACTB then assembles into the subcortical actin cytoskeleton (By similarity). During neuronal development, key reg µLator of neurite outgrowth, growth cone guidance and neuronal cell migration, presumably thro µgh the spatiotemporal fine tuning of protein synthesis, such as that of ACTB (By similarity). May reg µLate mRNA transport to activated synapses (By similarity). Binds to and stabilizes ABCB1/MDR-1 mRNA (By similarity). During interstinal wound repair, interacts with and stabilizes PTGS2 transcript. PTGS2 mRNA stabilization may be crucial for colonic mucosal wound healing (By similarity). Binds to the 3\'-UTR of IGF2 mRNA by a mechanism of cooperative and sequential dimerization and reg µLates IGF2 mRNA subcell µLar localization and translation. Binds to MYC mRNA, in the coding region instability determinant (CRD) of the open reading frame (ORF), hence prevents MYC cleavage by endonucleases and possibly microRNA targeting to MYC-CRD. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to the oncofetal H19 transcript and to the neuron-specific TAU mRNA and reg µLates their localizations. Binds to and stabilizes BTRC/FBW1A mRNA. Binds to the adenine-rich autoreg µLatory sequence (ARS) located in PABPC1 mRNA and represses its translation. PABPC1 mRNA-binding is stim µLated by PABPC1 protein. Prevents BTRC/FBW1A mRNA degradation by disrupting microRNA-dependent interaction with AGO2. Promotes the directed movement of tumor-derived cells by fine-tuning intracell µLar signaling networks. Binds to MAPK4 3\'-UTR and inhibits its translation. Interacts with PTEN transcript open reading frame (ORF) and prevents mRNA decay. This combined action on MAPK4 (down-reg µLation) and PTEN (up-reg µLation) antagonizes HSPB1 phosphorylation, consequently it prevents G-actin sequestration by phosphorylated HSPB1 allowing F-actin polymerization. Hence enhances the velocity of cell migration and stim µLates directed cell migration by PTEN-mod µLated polarization. Interacts with Hepatitis C virus (HCV) 5\'-UTR and 3\'-UTR and specifically enhances translation at the HCV IRES, but not 5\'-cap-dependent translation, possibly by recruiting eIF3. Interacts with HIV-1 GAG protein and blocks the formation of infectious HIV-1 particles. Reduces HIV-1 assembly by inhibiting viral RNA packaging, as well as assembly and processing of GAG protein on cell µLar membranes. During cell µLar stress, such as oxidative stress or heat shock, stabilizes target mRNAs that are recruited to stress gran µLes, including CD44, IGF2, MAPK4, MYC, PTEN, RAPGEF2 and RPS6KA5 transcripts.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF2BP1
Research Areas : Epigenetics and Nuclear Signaling
0,01 0.01 USD
IGF2BP1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF2BP1
GeneID : 10642
Uniprot : Q9NZI8
Specificity : IGF2BP1 Antibody detects endogenous levels of total IGF2BP1.
Immunogen : A syntheVolumed peptide derived from human IGF2BP1 corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838399
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6436-BP
Des# Blocking Peptide : IGF2BP1 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF2/IGF II
Volume : 50 µg
Protein Type : Cytokine
Product Grade : For Research Use.
Tag : None
Species : Human
Expressed In : E.coli
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGF2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF2
GeneID : 3481
Uniprot : P01344
Specificity : IGF2 Antibody detects endogenous levels of total IGF2.
Immunogen : A syntheVolumed peptide derived from human IGF2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Rabbit,Dog
Application : WB,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839722
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2516-BP
Des# Blocking Peptide : IGF2 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF1R/Insulin Receptor Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF1R,INSR
GeneID : 3480,3643
Uniprot : P08069/P06213
Specificity : IGF1R/Ins µLin Receptor Antibody detects endogenous levels of total IGF1R/Ins µLin Receptor.
Immunogen : A syntheVolumed peptide derived from human IGF1R/Ins µLin Receptor, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Bovine,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835009
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF6125-BP
Des# Blocking Peptide : IGF1R/Ins µLin Receptor Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF1R/INSR Antibody
Volume : 50 µg
Clone Number :
Aliases : IGF1R; Ins µLin-like growth factor 1 receptor; Ins µLin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; INSR; Ins µLin receptor; IR; CD antigen CD220
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069/P06213
Immunogen : SyntheVolumed peptide derived from Human IGF-IR around the non-phosphorylation site of Y1161.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R/INSR
Research Areas : Cancer;Developmental biology;Signal transduction
0,01 0.01 USD
IGF1R Beta Antibody
Volume : 100 µL
Host : Mouse
Clonality : Monoclonal
Isotype : IgG1
GeneName : IGF1R
GeneID : 3480
Uniprot : P08069
Specificity : IGF1R-Beta antibody detects endogenous levels of total IGF1R-Beta.
Immunogen : Purified recombinant fragment of human IGF1R-Beta expressed in E. Coli.
Storage : Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IHC,ELISA
Dilution : ELISA 1 : 10000, WB 1 : 500-1 : 2000, IHC 1 : 200-1 : 1000
Conj µgate : Unconj µgated
RRID : AB_2833601
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide :
Des# Blocking Peptide :
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF1R Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Recombinant Human Ins µLin-like growth factor 1 receptor protein (763-931AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of m µLtiple substrates, that function as signaling adapter proteins including, the ins µLin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways : the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The res µLt of activating the MAPK pathway is increased cell µLar proliferation, whereas activating the PI3K pathway inhibits apoptosis and stim µLates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa reg µLatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis thro µgh mTOR activation and triggers the antiapoptotic effects of IGFIR thro µgh phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also thro µgh the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In partic µLar activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1 which is able to directly associate with the IGF1R.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer; Developmental biology; Signal transduction
0,01 0.01 USD
IGF1R Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Recombinant Human Ins µLin-like growth factor 1 receptor protein (763-931AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of m µLtiple substrates, that function as signaling adapter proteins including, the ins µLin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways : the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The res µLt of activating the MAPK pathway is increased cell µLar proliferation, whereas activating the PI3K pathway inhibits apoptosis and stim µLates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa reg µLatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis thro µgh mTOR activation and triggers the antiapoptotic effects of IGFIR thro µgh phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also thro µgh the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In partic µLar activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1 which is able to directly associate with the IGF1R.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer; Developmental biology; Signal transduction
0,01 0.01 USD
IGF1R Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Recombinant Human Ins µLin-like growth factor 1 receptor protein (763-931AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of m µLtiple substrates, that function as signaling adapter proteins including, the ins µLin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways : the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The res µLt of activating the MAPK pathway is increased cell µLar proliferation, whereas activating the PI3K pathway inhibits apoptosis and stim µLates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa reg µLatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis thro µgh mTOR activation and triggers the antiapoptotic effects of IGFIR thro µgh phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also thro µgh the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In partic µLar activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1 which is able to directly associate with the IGF1R.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer; Developmental biology; Signal transduction
0,01 0.01 USD
IGF1R antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : IGF1R, also named as CD221 is a receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cell. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) (PMID : 6279656). Both the alpha and beta subunits are syntheVolumed from a single mRNA precursor. The precursor is then glycosylated, proteolytically cleaved, and crosslinked by cysteine bonds.
Immunogen : ins µLin-like growth factor 1 receptor
Aliases : CD221 IGFIR, IGFR, JTK13
Observed MW : 70 kDa,90-100 kDa, 130 kDa
Uniprot ID : P08069
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID : 3480
Research Area : Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience
0,01 0.01 USD
IGF1R (Ab 1346) Antibody
Volume : 100 µL
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Peptide sequence around aa.1344~1348 (Q-P-Y-A-H) derived from Human IGF-1R .
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : This receptor binds ins µLin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stim µLated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Adams, T.E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093
Baserga, R. et al. (2000) Oncogene 19, 5574-5581
Scheidegger, K.J. et al. (2000) J. Biol. Chem. 275, 38921-38928.
O'Connor R, et al. Mol Cell Biol 1997 Jan; 17(1) : 427-35
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer;Developmental biology;Signal transduction
0,01 0.01 USD
IGF1R (Ab 1280) Antibody
Volume : 100 µL
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Peptide sequence around aa. 1278~1282 (S-F-Y-Y-S ) derived from Human IGF-1R .
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : This receptor binds ins µLin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stim µLated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Adams, T.E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093
Baserga, R. et al. (2000) Oncogene 19, 5574-5581
Scheidegger, K.J. et al. (2000) J. Biol. Chem. 275, 38921-38928.
O'Connor R, et al. Mol Cell Biol 1997 Jan; 17(1) : 427-35
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer;Developmental biology;Signal transduction
0,01 0.01 USD
IGF1R (Ab 1165/1166) Antibody
Volume : 100 µL
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Peptide sequence around aa.1163~1167/1164~1168 (T-D-Y-Y-R-K) derived from Human IGF-1R .
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 1000
Background : This receptor binds ins µLin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stim µLated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Li S, et al. (1994) J Biol Chem; 269(51) : 32558-64.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer;Developmental biology;Signal transduction
0,01 0.01 USD
IGF1R (Ab 1161) Antibody
Volume : 100 µL
Clone Number :
Aliases : CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Ins µLin like growth factor 1 receptor antibody; Ins µLin like growth factor 1 receptor precursor antibody; Ins µLin-like growth factor 1 receptor beta chain antibody; Ins µLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08069
Immunogen : Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF : 1 : 100-1 : 200
Background : This receptor binds ins µLin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stim µLated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Li S, et al. (1994) J Biol Chem; 269(51).
Hernandez-Sanchez C, et al. (1995) J Biol Chem.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1R
Research Areas : Cancer;Developmental biology;Signal transduction
0,01 0.01 USD
IGF1B Specific antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : ins µLin-like growth factor 1(somatomedin C)
Aliases : IBP1 IGF I, IGF1 IGF1A, IGF1B, IGFI, Ins µLin like growth factor I, Mechano growth factor, MGF, Somatomedin C
Observed MW : 22 kDa
Uniprot ID : P05019
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 20 - 1 : 200
Gene ID : 3479
Research Area : Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience
0,01 0.01 USD
IGF1 Receptor Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF1R
GeneID : 3480
Uniprot : P08069
Specificity : IGF1 Receptor Antibody detects endogenous levels of total IGF1 Receptor.
Immunogen : A syntheVolumed peptide derived from human IGF1 Receptor, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat,Pig
Prediction : Bovine,Rabbit,Dog,Chicken,Xenopus
Application : WB,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2844702
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF4697-BP
Des# Blocking Peptide : IGF1 Receptor Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : IBP1 antibody; IGF I antibody; IGF IA antibody; IGF IB antibody; IGF-I antibody; Igf1 antibody; IGF1_HUMAN antibody; IGF1A antibody; IGFI antibody; IGFIA antibody; Ins µLin like growth factor 1 (somatomedin C) antibody; Ins µLin like growth factor 1 antibody; Ins µLin like growth factor IA antibody; Ins µLin like growth factor IB antibody; Ins µLin-like growth factor I antibody; Mechano growth factor antibody; MGF antibody; OTTHUMP00000195080 antibody; OTTHUMP00000195081 antibody; OTTHUMP00000195082 antibody; OTTHUMP00000195083 antibody; OTTHUMP00000195084 antibody; Somatomedia C antibody; Somatomedin C antibody; Somatomedin-C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05019
Immunogen : Recombinant Human Ins µLin-like growth factor I protein (49-118AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of m µLtiple substrates, that function as signaling adapter proteins including, the ins µLin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways : the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The res µLt of activating the MAPK pathway is increased cell µLar proliferation, whereas activating the PI3K pathway inhibits apoptosis and stim µLates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa reg µLatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis thro µgh mTOR activation and triggers the antiapoptotic effects of IGFIR thro µgh phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also thro µgh the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In partic µLar activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1 which is able to directly associate with the IGF1R.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1
Research Areas : Cancer; Developmental biology; Signal transduction
0,01 0.01 USD
IGF1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : IBP1 antibody; IGF I antibody; IGF IA antibody; IGF IB antibody; IGF-I antibody; Igf1 antibody; IGF1_HUMAN antibody; IGF1A antibody; IGFI antibody; IGFIA antibody; Ins µLin like growth factor 1 (somatomedin C) antibody; Ins µLin like growth factor 1 antibody; Ins µLin like growth factor IA antibody; Ins µLin like growth factor IB antibody; Ins µLin-like growth factor I antibody; Mechano growth factor antibody; MGF antibody; OTTHUMP00000195080 antibody; OTTHUMP00000195081 antibody; OTTHUMP00000195082 antibody; OTTHUMP00000195083 antibody; OTTHUMP00000195084 antibody; Somatomedia C antibody; Somatomedin C antibody; Somatomedin-C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05019
Immunogen : Recombinant Human Ins µLin-like growth factor I protein (49-118AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of m µLtiple substrates, that function as signaling adapter proteins including, the ins µLin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways : the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The res µLt of activating the MAPK pathway is increased cell µLar proliferation, whereas activating the PI3K pathway inhibits apoptosis and stim µLates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa reg µLatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis thro µgh mTOR activation and triggers the antiapoptotic effects of IGFIR thro µgh phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also thro µgh the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In partic µLar activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1 which is able to directly associate with the IGF1R.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1
Research Areas : Cancer; Developmental biology; Signal transduction
0,01 0.01 USD
IGF1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : IBP1 antibody; IGF I antibody; IGF IA antibody; IGF IB antibody; IGF-I antibody; Igf1 antibody; IGF1_HUMAN antibody; IGF1A antibody; IGFI antibody; IGFIA antibody; Ins µLin like growth factor 1 (somatomedin C) antibody; Ins µLin like growth factor 1 antibody; Ins µLin like growth factor IA antibody; Ins µLin like growth factor IB antibody; Ins µLin-like growth factor I antibody; Mechano growth factor antibody; MGF antibody; OTTHUMP00000195080 antibody; OTTHUMP00000195081 antibody; OTTHUMP00000195082 antibody; OTTHUMP00000195083 antibody; OTTHUMP00000195084 antibody; Somatomedia C antibody; Somatomedin C antibody; Somatomedin-C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05019
Immunogen : Recombinant Human Ins µLin-like growth factor I protein (49-118AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor tyrosine kinase which mediates actions of ins µLin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and ins µLin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of m µLtiple substrates, that function as signaling adapter proteins including, the ins µLin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways : the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The res µLt of activating the MAPK pathway is increased cell µLar proliferation, whereas activating the PI3K pathway inhibits apoptosis and stim µLates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa reg µLatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis thro µgh mTOR activation and triggers the antiapoptotic effects of IGFIR thro µgh phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also thro µgh the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In partic µLar activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1 which is able to directly associate with the IGF1R.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGF1
Research Areas : Cancer; Developmental biology; Signal transduction
0,01 0.01 USD
IGF1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGF1
GeneID : 3479
Uniprot : P05019
Specificity : IGF1 Antibody detects endogenous levels of total IGF1.
Immunogen : A syntheVolumed peptide derived from human IGF1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837876
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF5391-BP
Des# Blocking Peptide : IGF1 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IGF I R/IGF1R
Volume : 50 µg
Protein Type : Target proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGF I
Volume : 50 µg
Protein Type : Cytokine
Product Grade : For Research Use.
Tag : None
Species : Human
Expressed In : E.coli
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGF 1
Volume : 1mg
Protein Type : Cytokine
Product Grade : For GMP Manufacturing
Tag : None
Species : Human
Expressed In :
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGF Binding Protein 6/IGFBP 6
Volume : 50 µg
Protein Type : Cytokine
Product Grade : For Research Use.
Tag : C-6His
Species : Mouse
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGF Binding Protein 5/IGFBP 5
Volume : 20 µg
Protein Type : Target proteins
Product Grade : For Research Use.
Tag : C-6His-Avi
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IGBP1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IGBP1
GeneID : 3476
Uniprot : P78318
Specificity : IGBP1 Antibody detects endogenous levels of IGBP1.
Immunogen : A syntheVolumed peptide derived from human IGBP1.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15710-BP
Des# Blocking Peptide : IGBP1 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IgA Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName :
GeneID :
Uniprot : P01876/P01877
Specificity : IgA Antibody detects endogenous levels of total IgA.
Immunogen : A syntheVolumed peptide derived from human IgA, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Rat
Prediction :
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841767
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8563-BP
Des# Blocking Peptide : IgA Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
Ig lambda constant 2
Volume : 50 µg
Protein Type : Target proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
Ig kappa/Immunoglobulin Kappa Constant
Volume : 50 µg
Protein Type : Target proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
0,01 0.01 USD
IFT88 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IFT88
GeneID : 8100
Uniprot : Q13099
Specificity : IFT88 Antibody detects endogenous levels of total IFT88.
Immunogen : A syntheVolumed peptide derived from human IFT88, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat,Dog
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
Application : WB,IHC
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200
Conj µgate : Unconj µgated
RRID : AB_2844806
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12001-BP
Des# Blocking Peptide : IFT88 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IFT81 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IFT81
GeneID : 28981
Uniprot : Q8WYA0
Specificity : IFT81 Antibody detects endogenous levels of total IFT81.
Immunogen : A syntheVolumed peptide derived from human IFT81 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat,Dog
Prediction : Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus
Application : WB,IHC
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200
Conj µgate : Unconj µgated
RRID : AB_2844837
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12032-BP
Des# Blocking Peptide : IFT81 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IFT80 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : ATD2 antibody; Ift80 antibody; IFT80_HUMAN antibody; Intraflagellar transport 80 homolog (Chlamydomonas) antibody; Intraflagellar transport protein 80 homolog antibody; KIAA1374 antibody; WD repeat domain 56 antibody; WD repeat-containing protein 56 antibody; WDR56 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2H3
Immunogen : Recombinant Human Intraflagellar transport protein 80 homolog protein (1-268AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFT80
Research Areas : Others
0,01 0.01 USD
IFT80 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : ATD2 antibody; Ift80 antibody; IFT80_HUMAN antibody; Intraflagellar transport 80 homolog (Chlamydomonas) antibody; Intraflagellar transport protein 80 homolog antibody; KIAA1374 antibody; WD repeat domain 56 antibody; WD repeat-containing protein 56 antibody; WDR56 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2H3
Immunogen : Recombinant Human Intraflagellar transport protein 80 homolog protein (1-268AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFT80
Research Areas : Others
0,01 0.01 USD
IFT80 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : ATD2 antibody; Ift80 antibody; IFT80_HUMAN antibody; Intraflagellar transport 80 homolog (Chlamydomonas) antibody; Intraflagellar transport protein 80 homolog antibody; KIAA1374 antibody; WD repeat domain 56 antibody; WD repeat-containing protein 56 antibody; WDR56 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2H3
Immunogen : Recombinant Human Intraflagellar transport protein 80 homolog protein (1-268AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFT80
Research Areas : Others
0,01 0.01 USD
IFT80 antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Component of the intraflagellar transport(IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Immunogen : intraflagellar transport 80 homolog(Chlamydomonas)
Aliases : KIAA1374, WDR56
Observed MW : 88-90 kDa
Uniprot ID : Q9P2H3
Reactivity : Human, Mouse
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 57560
Research Area : Signal Transduction
0,01 0.01 USD
IFT74 Antibody
Volume : 50 µL
Clone Number :
Aliases : intraflagellar transport 74, Chlamydomonas, homolog of antibody; Capillary morphogenesis gene 1 protein antibody; Capillary morphogenesis protein 1 antibody; Ccdc2 antibody; CMG 1 antibody; CMG-1 antibody; Coiled-coil domain containing 2 antibody; Coiled-coil domain-containing protein 2 antibody; IFT74 antibody; IFT74_HUMAN antibody; intraflagellar transport 74 homolog (Chlamydomonas) antibody; intraflagellar transport 74 homolog antibody; Intraflagellar transport protein 74 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96LB3
Immunogen : Synthetic peptide of Human IFT74
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; ELISA : 1 : 1000-1 : 5000, IHC : 1 : 50-1 : 200
Background : Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71 a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in ad µLt and fetal kidney and testis, with lower levels of expression in ad µLt heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been s µggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional reg µLator of cyclin D2 in spermatocyte-derived cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFT74
Research Areas : Cardiovasc µLar
0,01 0.01 USD
IFT57 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : IFT57
GeneID : 55081
Uniprot : Q9NWB7
Specificity : IFT57 Antibody detects endogenous levels of total IFT57.
Immunogen : A syntheVolumed peptide derived from human IFT57, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat,Dog
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200
Conj µgate : Unconj µgated
RRID : AB_2844852
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12047-BP
Des# Blocking Peptide : IFT57 Blocking peptide
Blocking Peptide Price : $549 CAD
0,01 0.01 USD
IFT52 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : IFT52 antibody; C20orf9 antibody; NGD5 antibody; CGI-53 antibody; Intraflagellar transport protein 52 homolog antibody; Protein NGD5 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y366
Immunogen : Recombinant Human Intraflagellar transport protein 52 homolog protein (325-434AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia (PubMed : 27466190). Required for the anterograde transport of IFT88 (PubMed : 27466190).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFT52
Research Areas :
0,01 0.01 USD
IFT52 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : IFT52 antibody; C20orf9 antibody; NGD5 antibody; CGI-53 antibody; Intraflagellar transport protein 52 homolog antibody; Protein NGD5 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y366
Immunogen : Recombinant Human Intraflagellar transport protein 52 homolog protein (325-434AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia (PubMed : 27466190). Required for the anterograde transport of IFT88 (PubMed : 27466190).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFT52
Research Areas :
0,01 0.01 USD