Se rendre au contenu
Alb Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Alb 1 antibody; alb antibody; ALBU_RAT antibody; Albumin antibody; Serum albumin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P02770
Immunogen : Serum Albumin purified from Rat serum (Native Protein)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications :
Background : Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and dr µgs. Its main function is the reg µLation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Alb
Research Areas : Cardiovasc µLar
2.848,56 € 2848.56 EUR
Alb Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Alb 1 antibody; alb antibody; ALBU_RAT antibody; Albumin antibody; Serum albumin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P02770
Immunogen : Serum Albumin purified from Rat serum (Native Protein)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and dr µgs. Its main function is the reg µLation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Alb
Research Areas : Cardiovasc µLar
2.848,56 € 2848.56 EUR
Alb Antibody
Volume : 50 µg
Clone Number :
Aliases : Alb 1 antibody; alb antibody; ALBU_RAT antibody; Albumin antibody; Serum albumin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P02770
Immunogen : Serum Albumin purified from Rat serum (Native Protein)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and dr µgs. Its main function is the reg µLation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Alb
Research Areas : Cardiovasc µLar
2.848,56 € 2848.56 EUR
ALAS2 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 @aminolev µLinate synthase erythroid specific antibody; 5 aminolev µLinate synthase 2 antibody; 5 aminolev µLinate synthase 5 aminolev µLinate synthase 2 antibody; 5 aminolev µLinate synthase erythroid specific mitochondrial antibody; 5 aminolev µLinic acid synthase 2 antibody; 5 aminolev µLinic acid synthase antibody; 5-aminolev µLinate synthase antibody; 5-aminolev µLinic acid synthase 2 antibody; Alas 2 antibody; ALAS antibody; ALAS E antibody; ALAS; erythroid antibody; ALAS-E antibody; Alas2 antibody; ALASE antibody; Aminolev µLinate delta synthase 2 antibody; Aminolev µLinic acid synthase 2; erythroid antibody; ANH1 antibody; ASB antibody; Delta ALA synthase 2 antibody; Delta ALA synthetase antibody; Delta aminolev µLinate synthase 2 antibody; Delta aminolev µLinate synthase antibody; Delta-ALA synthase 2 antibody; Delta-aminolev µLinate synthase 2 antibody; Erythroid specific ALAS antibody; erythroid-specific antibody; FLJ93603 antibody; HEM0_HUMAN antibody; mitochondrial antibody; OTTHUMP00000023388 antibody; OTTHUMP00000023389 antibody; OTTMUSP00000020679 antibody; RP23-338A17.1 antibody; SIDBA1 antibody; XLDPP antibody; XLEPP antibody; XLSA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22557
Immunogen : Recombinant Human 5-aminolev µLinate synthase, erythroid-specific, mitochondrial protein (50-587AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : mitochondrial inner membrane, mitochondrial matrix, mitochondrion, 5-aminolev µLinate synthase activity, coenzyme binding, glycine binding, cell µLar iron ion homeostasis, erythrocyte differentiation, heme biosynthetic process, hemoglobin biosynthetic process
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALAS2
Research Areas : Others
2.848,56 € 2848.56 EUR
ALAS2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 @aminolev µLinate synthase erythroid specific antibody; 5 aminolev µLinate synthase 2 antibody; 5 aminolev µLinate synthase 5 aminolev µLinate synthase 2 antibody; 5 aminolev µLinate synthase erythroid specific mitochondrial antibody; 5 aminolev µLinic acid synthase 2 antibody; 5 aminolev µLinic acid synthase antibody; 5-aminolev µLinate synthase antibody; 5-aminolev µLinic acid synthase 2 antibody; Alas 2 antibody; ALAS antibody; ALAS E antibody; ALAS; erythroid antibody; ALAS-E antibody; Alas2 antibody; ALASE antibody; Aminolev µLinate delta synthase 2 antibody; Aminolev µLinic acid synthase 2; erythroid antibody; ANH1 antibody; ASB antibody; Delta ALA synthase 2 antibody; Delta ALA synthetase antibody; Delta aminolev µLinate synthase 2 antibody; Delta aminolev µLinate synthase antibody; Delta-ALA synthase 2 antibody; Delta-aminolev µLinate synthase 2 antibody; Erythroid specific ALAS antibody; erythroid-specific antibody; FLJ93603 antibody; HEM0_HUMAN antibody; mitochondrial antibody; OTTHUMP00000023388 antibody; OTTHUMP00000023389 antibody; OTTMUSP00000020679 antibody; RP23-338A17.1 antibody; SIDBA1 antibody; XLDPP antibody; XLEPP antibody; XLSA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22557
Immunogen : Recombinant Human 5-aminolev µLinate synthase, erythroid-specific, mitochondrial protein (50-587AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : mitochondrial inner membrane, mitochondrial matrix, mitochondrion, 5-aminolev µLinate synthase activity, coenzyme binding, glycine binding, cell µLar iron ion homeostasis, erythrocyte differentiation, heme biosynthetic process, hemoglobin biosynthetic process
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALAS2
Research Areas : Others
2.848,56 € 2848.56 EUR
ALAS2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 @aminolev µLinate synthase erythroid specific antibody; 5 aminolev µLinate synthase 2 antibody; 5 aminolev µLinate synthase 5 aminolev µLinate synthase 2 antibody; 5 aminolev µLinate synthase erythroid specific mitochondrial antibody; 5 aminolev µLinic acid synthase 2 antibody; 5 aminolev µLinic acid synthase antibody; 5-aminolev µLinate synthase antibody; 5-aminolev µLinic acid synthase 2 antibody; Alas 2 antibody; ALAS antibody; ALAS E antibody; ALAS; erythroid antibody; ALAS-E antibody; Alas2 antibody; ALASE antibody; Aminolev µLinate delta synthase 2 antibody; Aminolev µLinic acid synthase 2; erythroid antibody; ANH1 antibody; ASB antibody; Delta ALA synthase 2 antibody; Delta ALA synthetase antibody; Delta aminolev µLinate synthase 2 antibody; Delta aminolev µLinate synthase antibody; Delta-ALA synthase 2 antibody; Delta-aminolev µLinate synthase 2 antibody; Erythroid specific ALAS antibody; erythroid-specific antibody; FLJ93603 antibody; HEM0_HUMAN antibody; mitochondrial antibody; OTTHUMP00000023388 antibody; OTTHUMP00000023389 antibody; OTTMUSP00000020679 antibody; RP23-338A17.1 antibody; SIDBA1 antibody; XLDPP antibody; XLEPP antibody; XLSA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22557
Immunogen : Recombinant Human 5-aminolev µLinate synthase, erythroid-specific, mitochondrial protein (50-587AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : mitochondrial inner membrane, mitochondrial matrix, mitochondrion, 5-aminolev µLinate synthase activity, coenzyme binding, glycine binding, cell µLar iron ion homeostasis, erythrocyte differentiation, heme biosynthetic process, hemoglobin biosynthetic process
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALAS2
Research Areas : Others
2.848,56 € 2848.56 EUR
ALAS2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ALAS2
GeneID : 212
Uniprot : P22557
Specificity : ALAS2 Antibody detects endogenous levels of ALAS2.
Immunogen : A syntheVolumed peptide derived from human ALAS2.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15265-BP
Des# Blocking Peptide : ALAS2 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
ALAS1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 aminolev µLinate synthase antibody; 5 aminolev µLinate synthase nonspecific mitochondrial antibody; 5 aminolev µLinic acid synthase antibody; 5-aminolev µLinate synthase antibody; 5-aminolev µLinic acid synthase 1 antibody; Alas 1 antibody; ALAS 3 antibody; ALAS antibody; ALAS H antibody; ALAS HOUSEKEEPING TYPE antibody; ALAS N antibody; ALAS-H antibody; alaS1 antibody; ALAS3 antibody; ALASH antibody; Aminolev µLinate delta synthase 1 antibody; Aminolev µLinic acid synthase 1 antibody; Delta ALA synthetase antibody; Delta aminolev µLinate synthase antibody; Delta-ALA synthase 1 antibody; Delta-aminolev µLinate synthase 1 antibody; HEM1_HUMAN antibody; MIG 4 antibody; MIG4 antibody; Migration inducing protein 4 antibody; mitochondrial antibody; nonspecific antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13196
Immunogen : Recombinant Human 5-aminolev µLinate synthase, nonspecific, mitochondrial protein (57-285AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : cytoplasm, mitochondrial matrix, mitochondrion, nucleoplasm, 5-aminolev µLinate synthase activity, identical protein binding, heme biosynthetic process, mitochondrion organization
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALAS1
Research Areas : Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
ALAS1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 aminolev µLinate synthase antibody; 5 aminolev µLinate synthase nonspecific mitochondrial antibody; 5 aminolev µLinic acid synthase antibody; 5-aminolev µLinate synthase antibody; 5-aminolev µLinic acid synthase 1 antibody; Alas 1 antibody; ALAS 3 antibody; ALAS antibody; ALAS H antibody; ALAS HOUSEKEEPING TYPE antibody; ALAS N antibody; ALAS-H antibody; alaS1 antibody; ALAS3 antibody; ALASH antibody; Aminolev µLinate delta synthase 1 antibody; Aminolev µLinic acid synthase 1 antibody; Delta ALA synthetase antibody; Delta aminolev µLinate synthase antibody; Delta-ALA synthase 1 antibody; Delta-aminolev µLinate synthase 1 antibody; HEM1_HUMAN antibody; MIG 4 antibody; MIG4 antibody; Migration inducing protein 4 antibody; mitochondrial antibody; nonspecific antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13196
Immunogen : Recombinant Human 5-aminolev µLinate synthase, nonspecific, mitochondrial protein (57-285AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : cytoplasm, mitochondrial matrix, mitochondrion, nucleoplasm, 5-aminolev µLinate synthase activity, identical protein binding, heme biosynthetic process, mitochondrion organization
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALAS1
Research Areas : Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
ALAS1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 aminolev µLinate synthase antibody; 5 aminolev µLinate synthase nonspecific mitochondrial antibody; 5 aminolev µLinic acid synthase antibody; 5-aminolev µLinate synthase antibody; 5-aminolev µLinic acid synthase 1 antibody; Alas 1 antibody; ALAS 3 antibody; ALAS antibody; ALAS H antibody; ALAS HOUSEKEEPING TYPE antibody; ALAS N antibody; ALAS-H antibody; alaS1 antibody; ALAS3 antibody; ALASH antibody; Aminolev µLinate delta synthase 1 antibody; Aminolev µLinic acid synthase 1 antibody; Delta ALA synthetase antibody; Delta aminolev µLinate synthase antibody; Delta-ALA synthase 1 antibody; Delta-aminolev µLinate synthase 1 antibody; HEM1_HUMAN antibody; MIG 4 antibody; MIG4 antibody; Migration inducing protein 4 antibody; mitochondrial antibody; nonspecific antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13196
Immunogen : Recombinant Human 5-aminolev µLinate synthase, nonspecific, mitochondrial protein (57-285AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : cytoplasm, mitochondrial matrix, mitochondrion, nucleoplasm, 5-aminolev µLinate synthase activity, identical protein binding, heme biosynthetic process, mitochondrion organization
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALAS1
Research Areas : Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
Alas1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ALAS1
GeneID : 211
Uniprot : P13196
Specificity : Alas1 Antibody detects endogenous levels of total Alas1.
Immunogen : A syntheVolumed peptide derived from human Alas1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2840889
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2900-BP
Des# Blocking Peptide : Alas1 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AlaRS antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : AARS(alanyl-tRNA synthetase) is also named as AlaRS(alanine tRNA ligase 1 cytoplasmic), renal carcinoma antigen NY-REN-42 and belongs to the class-II aminoacyl-tRNA synthetase family. It can interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. AARS consists of three domains : the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stim µLating deacylation of misacylated tRNAs(PMID : 19661429).
Immunogen : alanyl-tRNA synthetase
Aliases : AARS, Alanine tRNA ligase, alanyl tRNA synthetase, AlaRS
Observed MW : 107 kDa
Uniprot ID : P49588
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF, IP
Recommended dilution : WB : 1 : 200-1 : 1000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200; IP : 1 : 200-1 : 2000
Gene ID :
Research Area : Neuroscience, Metabolism
310,20 € 310.2 EUR
Alanine Transaminase Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : GPT
GeneID : 2875
Uniprot : P24298
Specificity : Alanine Transaminase Antibody detects endogenous levels of total Alanine Transaminase.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14428-BP
Des# Blocking Peptide : Alanine Transaminase Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
ALADIN antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The protein encoded by this gene is a member of the WD-repeat family of reg µLatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen : achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
Aliases : AAA, AAAS, AAASb, ADRACALA, ADRACALIN, ALADIN, DKFZp586G1624, GL003
Observed MW : 60 kDa
Uniprot ID : Q9NRG9
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200; IF : 1 : 50 - 1 : 200
Gene ID : 8086
Research Area : Neuroscience
310,20 € 310.2 EUR
ALAD Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ALAD
GeneID : 210
Uniprot : P13716
Specificity : ALAD Antibody detects endogenous levels of ALAD.
Immunogen : A syntheVolumed peptide derived from human ALAD.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14597-BP
Des# Blocking Peptide : ALAD Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
alaC Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : alaC antibody; yfdZ antibody; b2379 antibody; JW2376 antibody; Glutamate-pyruvate aminotransferase AlaC antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P77434
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaC protein (1-412AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaC
Research Areas : Others
2.848,56 € 2848.56 EUR
alaC Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : alaC antibody; yfdZ antibody; b2379 antibody; JW2376 antibody; Glutamate-pyruvate aminotransferase AlaC antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P77434
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaC protein (1-412AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications :
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaC
Research Areas : Others
2.848,56 € 2848.56 EUR
alaC Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : alaC antibody; yfdZ antibody; b2379 antibody; JW2376 antibody; Glutamate-pyruvate aminotransferase AlaC antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P77434
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaC protein (1-412AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaC
Research Areas : Others
2.848,56 € 2848.56 EUR
alaC Antibody
Volume : 50 µg
Clone Number :
Aliases : alaC antibody; yfdZ antibody; b2379 antibody; JW2376 antibody; Glutamate-pyruvate aminotransferase AlaC antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P77434
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaC protein (1-412AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaC
Research Areas : Others
2.848,56 € 2848.56 EUR
alaA Antibody HRP conjugated
Volume : 50 µL
Clone Number :
Aliases : alaA antibody; yfbQ antibody; b2290 antibody; JW2287Glutamate-pyruvate aminotransferase AlaA antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli(strain K12)
UniProt ID : P0A959
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaA protein (1-405AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaA
Research Areas : Others
2.848,56 € 2848.56 EUR
alaA Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : alaA antibody; yfbQ antibody; b2290 antibody; JW2287Glutamate-pyruvate aminotransferase AlaA antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli(strain K12)
UniProt ID : P0A959
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaA protein (1-405AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications :
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaA
Research Areas : Others
2.848,56 € 2848.56 EUR
alaA Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : alaA antibody; yfbQ antibody; b2290 antibody; JW2287Glutamate-pyruvate aminotransferase AlaA antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli(strain K12)
UniProt ID : P0A959
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaA protein (1-405AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaA
Research Areas : Others
2.848,56 € 2848.56 EUR
alaA Antibody
Volume : 50 µL
Clone Number :
Aliases : alaA antibody; yfbQ antibody; b2290 antibody; JW2287Glutamate-pyruvate aminotransferase AlaA antibody; EC 2.6.1.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli(strain K12)
UniProt ID : P0A959
Immunogen : Recombinant Escherichia coli Glutamate-pyruvate aminotransferase AlaA protein (1-405AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA, WB; Recommended dilution : WB : 1 : 1000-1 : 5000
Background : Involved in the biosynthesis of alanine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : alaA
Research Areas : Others
2.848,56 € 2848.56 EUR
AL2S7 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK15
GeneID : 65061
Uniprot : Q96Q40
Specificity : AL2S7 Antibody detects endogenous levels of total AL2S7.
Immunogen : A syntheVolumed peptide derived from human AL2S7, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Sheep,Rabbit,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2834303
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF0509-BP
Des# Blocking Peptide : AL2S7 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKTIP Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : AKT interacting protein antibody; AKT-interacting protein antibody; AKTIP antibody; AKTIP_HUMAN antibody; FT 1 antibody; FT1 antibody; Fused toes homolog antibody; Fused toes protein homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H8T0
Immunogen : Recombinant Human AKT-interacting protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesic µLar protein sorting complex (the HOPS complex). Reg µLates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKTIP
Research Areas : Others
2.848,56 € 2848.56 EUR
AKTIP Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : AKT interacting protein antibody; AKT-interacting protein antibody; AKTIP antibody; AKTIP_HUMAN antibody; FT 1 antibody; FT1 antibody; Fused toes homolog antibody; Fused toes protein homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H8T0
Immunogen : Recombinant Human AKT-interacting protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesic µLar protein sorting complex (the HOPS complex). Reg µLates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKTIP
Research Areas : Others
2.848,56 € 2848.56 EUR
AKTIP Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AKT interacting protein antibody; AKT-interacting protein antibody; AKTIP antibody; AKTIP_HUMAN antibody; FT 1 antibody; FT1 antibody; Fused toes homolog antibody; Fused toes protein homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H8T0
Immunogen : Recombinant Human AKT-interacting protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesic µLar protein sorting complex (the HOPS complex). Reg µLates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKTIP
Research Areas : Others
2.848,56 € 2848.56 EUR
AKTIP antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conj µgating enzymes but lacks the conserved cysteine residue that enables those enzymes to conj µgate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and mod µLates PKB activity by enhancing the phosphorylation of PKB's reg µLatory sites. Alternative splicing res µLts in two transcript variants encoding the same protein.
Immunogen : AKT interacting protein
Aliases : AKT interacting protein, AKTIP, FT1 FTS, Fused toes protein homolog
Observed MW : 36 kDa
Uniprot ID : Q9H8T0
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200
Gene ID : 64400
Research Area : Metabolism
310,20 € 310.2 EUR
AKT3 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Akt3 antibody; AKT3 kinase antibody; AKT3_HUMAN antibody; DKFZp434N0250 antibody; MPPH antibody; PKB gamma antibody; PKBG antibody; PRKBG antibody; Protein kinase Akt-3 antibody; Protein Kinase AKT3 antibody; Protein kinase B gamma antibody; RAC gamma antibody; RAC gamma serine/threonine protein kinase antibody; RAC-gamma serine/threonine-protein kinase antibody; RAC-PK-gamma antibody; RACPK Gamma antibody; Serine threonine protein kinase Akt 3 antibody; Serine threonine protein kinase Akt3 antibody; STK 2 antibody; STK-2 antibody; STK2 antibody; V akt murine thymoma viral oncogene homolog 3 (protein kinase B; gamma) antibody; V akt murine thymoma viral oncogene homolog 3 antibody; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y243
Immunogen : Recombinant Human RAC-gamma serine/threonine-protein kinase protein (1-164AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molec µLe in up-reg µLation and down-reg µLation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cell µLar energy demands. Down-reg µLation by RNA interference reduces the expression of the phosphorylated form of BAD, res µLting in the induction of caspase-dependent apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT3
Research Areas : Cancer; Signal transduction
2.848,56 € 2848.56 EUR
AKT3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Akt3 antibody; AKT3 kinase antibody; AKT3_HUMAN antibody; DKFZp434N0250 antibody; MPPH antibody; PKB gamma antibody; PKBG antibody; PRKBG antibody; Protein kinase Akt-3 antibody; Protein Kinase AKT3 antibody; Protein kinase B gamma antibody; RAC gamma antibody; RAC gamma serine/threonine protein kinase antibody; RAC-gamma serine/threonine-protein kinase antibody; RAC-PK-gamma antibody; RACPK Gamma antibody; Serine threonine protein kinase Akt 3 antibody; Serine threonine protein kinase Akt3 antibody; STK 2 antibody; STK-2 antibody; STK2 antibody; V akt murine thymoma viral oncogene homolog 3 (protein kinase B; gamma) antibody; V akt murine thymoma viral oncogene homolog 3 antibody; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y243
Immunogen : Recombinant Human RAC-gamma serine/threonine-protein kinase protein (1-164AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molec µLe in up-reg µLation and down-reg µLation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cell µLar energy demands. Down-reg µLation by RNA interference reduces the expression of the phosphorylated form of BAD, res µLting in the induction of caspase-dependent apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT3
Research Areas : Cancer; Signal transduction
2.848,56 € 2848.56 EUR
AKT3 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Akt3 antibody; AKT3 kinase antibody; AKT3_HUMAN antibody; DKFZp434N0250 antibody; MPPH antibody; PKB gamma antibody; PKBG antibody; PRKBG antibody; Protein kinase Akt-3 antibody; Protein Kinase AKT3 antibody; Protein kinase B gamma antibody; RAC gamma antibody; RAC gamma serine/threonine protein kinase antibody; RAC-gamma serine/threonine-protein kinase antibody; RAC-PK-gamma antibody; RACPK Gamma antibody; Serine threonine protein kinase Akt 3 antibody; Serine threonine protein kinase Akt3 antibody; STK 2 antibody; STK-2 antibody; STK2 antibody; V akt murine thymoma viral oncogene homolog 3 (protein kinase B; gamma) antibody; V akt murine thymoma viral oncogene homolog 3 antibody; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y243
Immunogen : Recombinant Human RAC-gamma serine/threonine-protein kinase protein (1-164AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molec µLe in up-reg µLation and down-reg µLation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cell µLar energy demands. Down-reg µLation by RNA interference reduces the expression of the phosphorylated form of BAD, res µLting in the induction of caspase-dependent apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT3
Research Areas : Cancer; Signal transduction
2.848,56 € 2848.56 EUR
AKT3 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKT3
GeneID : 10000
Uniprot : Q9Y243
Specificity : AKT3 Antibody detects endogenous levels of total AKT3.
Immunogen : A syntheVolumed peptide derived from human AKT3, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human,Mouse,Rat
Prediction :
Application : WB,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839860
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2654-BP
Des# Blocking Peptide : AKT3 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKT2 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Akt2 antibody; AKT2_HUMAN antibody; HIHGHH antibody; Murine thymoma viral (v-akt) homolog 2 antibody; murine thymoma viral (v-akt) homolog-2 antibody; Oncogene AKT2 protein kinase B beta antibody; PKB antibody; PKB beta antibody; PKBB antibody; PKBBETA antibody; PRKBB antibody; Protein kinase Akt 2 antibody; Protein kinase Akt-2 antibody; Protein kinase B beta antibody; RAC beta antibody; rac protein kinase beta antibody; RAC-BETA antibody; RAC-beta serine/threonine-protein kinase antibody; RAC-PK-beta antibody; RACbeta antibody; v akt murine thymoma viral oncogene homolog 2 antibody; V-AKT murine thymoma viral oncogene homolog 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31751
Immunogen : Recombinant Human RAC-beta serine/threonine-protein kinase protein (2-481AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Ref.10 Ref.20 One of the few specific substrates of AKT2 identified recently is PITX2. Phosphorylation of PITX2 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1. AKT2 seems also to be the principal isoform responsibleof the reg µLation of glucose uptake. Phosphorylates C2CD5 on 'Ser-197' during ins µLin-stim µLated adipocytes. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Down-reg µLation by RNA interference reduces the expression of the phosphorylated form of BAD, res µLting in the induction of caspase-dependent apoptosis. Phosphorylates CLK2 on 'Thr-343'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKT2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Akt2 antibody; AKT2_HUMAN antibody; HIHGHH antibody; Murine thymoma viral (v-akt) homolog 2 antibody; murine thymoma viral (v-akt) homolog-2 antibody; Oncogene AKT2 protein kinase B beta antibody; PKB antibody; PKB beta antibody; PKBB antibody; PKBBETA antibody; PRKBB antibody; Protein kinase Akt 2 antibody; Protein kinase Akt-2 antibody; Protein kinase B beta antibody; RAC beta antibody; rac protein kinase beta antibody; RAC-BETA antibody; RAC-beta serine/threonine-protein kinase antibody; RAC-PK-beta antibody; RACbeta antibody; v akt murine thymoma viral oncogene homolog 2 antibody; V-AKT murine thymoma viral oncogene homolog 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31751
Immunogen : Recombinant Human RAC-beta serine/threonine-protein kinase protein (2-481AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Ref.10 Ref.20 One of the few specific substrates of AKT2 identified recently is PITX2. Phosphorylation of PITX2 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1. AKT2 seems also to be the principal isoform responsibleof the reg µLation of glucose uptake. Phosphorylates C2CD5 on 'Ser-197' during ins µLin-stim µLated adipocytes. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Down-reg µLation by RNA interference reduces the expression of the phosphorylated form of BAD, res µLting in the induction of caspase-dependent apoptosis. Phosphorylates CLK2 on 'Thr-343'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKT2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Akt2 antibody; AKT2_HUMAN antibody; HIHGHH antibody; Murine thymoma viral (v-akt) homolog 2 antibody; murine thymoma viral (v-akt) homolog-2 antibody; Oncogene AKT2 protein kinase B beta antibody; PKB antibody; PKB beta antibody; PKBB antibody; PKBBETA antibody; PRKBB antibody; Protein kinase Akt 2 antibody; Protein kinase Akt-2 antibody; Protein kinase B beta antibody; RAC beta antibody; rac protein kinase beta antibody; RAC-BETA antibody; RAC-beta serine/threonine-protein kinase antibody; RAC-PK-beta antibody; RACbeta antibody; v akt murine thymoma viral oncogene homolog 2 antibody; V-AKT murine thymoma viral oncogene homolog 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31751
Immunogen : Recombinant Human RAC-beta serine/threonine-protein kinase protein (2-481AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Ref.10 Ref.20 One of the few specific substrates of AKT2 identified recently is PITX2. Phosphorylation of PITX2 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1. AKT2 seems also to be the principal isoform responsibleof the reg µLation of glucose uptake. Phosphorylates C2CD5 on 'Ser-197' during ins µLin-stim µLated adipocytes. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Down-reg µLation by RNA interference reduces the expression of the phosphorylated form of BAD, res µLting in the induction of caspase-dependent apoptosis. Phosphorylates CLK2 on 'Thr-343'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKT2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKT2
GeneID : 208
Uniprot : P31751
Specificity : AKT2 Antibody detects endogenous levels of total AKT2.
Immunogen : A syntheVolumed peptide derived from human Akt2, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835122
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF6264-BP
Des# Blocking Peptide : AKT2 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKT2 (Ab 474) Antibody
Volume : 100 µL
Clone Number :
Aliases : Akt2 antibody; AKT2_HUMAN antibody; HIHGHH antibody; Murine thymoma viral (v-akt) homolog 2 antibody; murine thymoma viral (v-akt) homolog-2 antibody; Oncogene AKT2 protein kinase B beta antibody; PKB antibody; PKB beta antibody; PKBB antibody; PKBBETA antibody; PRKBB antibody; Protein kinase Akt 2 antibody; Protein kinase Akt-2 antibody; Protein kinase B beta antibody; RAC beta antibody; rac protein kinase beta antibody; RAC-BETA antibody; RAC-beta serine/threonine-protein kinase antibody; RAC-PK-beta antibody; RACbeta antibody; v akt murine thymoma viral oncogene homolog 2 antibody; V-AKT murine thymoma viral oncogene homolog 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31751
Immunogen : Peptide sequence around aa. 472~476 (Q-F-S-Y-S) derived from Human Akt2.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : General protein kinase capable of phosphorylating several known proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT2
Research Areas : Cancer?Cardiovasc µLar;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1S1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : 40 kDa proline rich AKT substrate antibody; 40 kDa proline-rich AKT substrate antibody; AKT1 S1 antibody; AKT1 substrate 1 (proline rich) antibody; AKT1 substrate 1 antibody; AKT1S 1 antibody; AKT1S1 antibody; AKTS1_HUMAN antibody; Lobe antibody; MGC2865 antibody; PRAS 40 antibody; PRAS antibody; PRAS40 antibody; Proline rich akt substrate antibody; Proline rich Akt substrate 40 kDa antibody; Proline-rich AKT1 substrate 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B36
Immunogen : Recombinant Human Proline-rich AKT1 substrate 1 protein (52-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Subunit of mTORC1 which reg µLates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stim µLated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Rag µLator complex and the Rag GTPases. Activated mTORC1 up-reg µLates protein synthesis by phosphorylating key reg µLators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at \'Thr-389\', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1 AKT1S1 negatively reg µLates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins. Inhibits RHEB-GTP-dependent mTORC1 activation. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. May also play a role in nerve growth factor-mediated neuroprotection.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1S1
Research Areas : Neuroscience; Cell biology; Signal transduction
2.848,56 € 2848.56 EUR
AKT1S1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 40 kDa proline rich AKT substrate antibody; 40 kDa proline-rich AKT substrate antibody; AKT1 S1 antibody; AKT1 substrate 1 (proline rich) antibody; AKT1 substrate 1 antibody; AKT1S 1 antibody; AKT1S1 antibody; AKTS1_HUMAN antibody; Lobe antibody; MGC2865 antibody; PRAS 40 antibody; PRAS antibody; PRAS40 antibody; Proline rich akt substrate antibody; Proline rich Akt substrate 40 kDa antibody; Proline-rich AKT1 substrate 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B36
Immunogen : Recombinant Human Proline-rich AKT1 substrate 1 protein (52-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Subunit of mTORC1 which reg µLates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stim µLated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Rag µLator complex and the Rag GTPases. Activated mTORC1 up-reg µLates protein synthesis by phosphorylating key reg µLators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at \'Thr-389\', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1 AKT1S1 negatively reg µLates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins. Inhibits RHEB-GTP-dependent mTORC1 activation. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. May also play a role in nerve growth factor-mediated neuroprotection.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1S1
Research Areas : Neuroscience; Cell biology; Signal transduction
2.848,56 € 2848.56 EUR
AKT1S1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 40 kDa proline rich AKT substrate antibody; 40 kDa proline-rich AKT substrate antibody; AKT1 S1 antibody; AKT1 substrate 1 (proline rich) antibody; AKT1 substrate 1 antibody; AKT1S 1 antibody; AKT1S1 antibody; AKTS1_HUMAN antibody; Lobe antibody; MGC2865 antibody; PRAS 40 antibody; PRAS antibody; PRAS40 antibody; Proline rich akt substrate antibody; Proline rich Akt substrate 40 kDa antibody; Proline-rich AKT1 substrate 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B36
Immunogen : Recombinant Human Proline-rich AKT1 substrate 1 protein (52-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Subunit of mTORC1 which reg µLates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stim µLated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Rag µLator complex and the Rag GTPases. Activated mTORC1 up-reg µLates protein synthesis by phosphorylating key reg µLators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at \'Thr-389\', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1 AKT1S1 negatively reg µLates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins. Inhibits RHEB-GTP-dependent mTORC1 activation. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. May also play a role in nerve growth factor-mediated neuroprotection.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1S1
Research Areas : Neuroscience; Cell biology; Signal transduction
2.848,56 € 2848.56 EUR
AKT1S1 antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : Proline-rich AKT1 substrate 1
Aliases : AKT1S1 Lobe, PRAS40, AKT1 substrate 1
Observed MW : 50 kDa
Uniprot ID : Q96B36
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 20 - 1 : 200
Gene ID : 84335
Research Area : Signal Transduction, Neuroscience
331,65 € 331.65 EUR
AKT1/AKT3 Antibody
Volume : 50 µg
Clone Number :
Aliases : AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT3; PKBG; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein ki
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749/Q9Y243
Immunogen : SyntheVolumed peptide derived from Human Akt1/3 around the non-phosphorylation site of Y437/434.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1/AKT3
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
171,60 € 171.6 EUR
AKT1/AKT3 (Ab 437/434) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : SyntheVolumed non-phosphopeptide derived from Human AKT1/3 around the phosphorylation site of tyrosine 437/434 (T-R-Y(p)-F-D).
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 3000
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53. AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation mod µLates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform hasa more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.

Jones P.F., Proc. Natl. Acad. Sci. U.S.A. 88 : 4171-4175(1991).
Matsubara A., Diabetologia 44 : 910-913(2001).
The MGC Project Team; Genome Res. 14 : 2121-2127(2004).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1/AKT3
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1/AKT2/AKT3 Antibody
Volume : 50 µg
Clone Number :
Aliases : AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749/P31751/Q9Y243
Immunogen : SyntheVolumed peptide derived from Human Akt around the non-phosphorylation site of T308.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1/AKT2/AKT3
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
171,60 € 171.6 EUR
AKT1/AKT2/AKT3 (Ab 315/316/312) Antibody
Volume : 100 µL
Clone Number :
Aliases : RAC-PK-alpha; Protein kinase B;
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749/P31751/Q9Y243
Immunogen : Peptide sequence around aa.313~317/314~318/310~314 (P-E-Y-L-A) derived from Human AKT1/AKT2/AKT3.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, IHC; IHC : 1 : 50-1 : 100
Background : General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating ins µLin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the ins µLin-induced activation of glycogen synthase. /General protein kinase capable of phosphorylating several known proteins. /IGF-1 leads to the activation of AKT3, which may play a role in reg µLating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site co µLd still be stim µLated but to a lesser extent.

Nelms K, et al. (1999) Annu Rev Immunol. 17 : 701-738.
Malabarba M G, et al. (1996) Biochem. J. 319 : 865-872.
Hou J, et al. (1994) Science. 265 : 1701-1706.
Quelle F W, et al. (1995) Mol Cell Biol. 15 : 3336-3343.
Takeda K, et al. (1996) Nature. 380 : 627-630.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1/AKT2/AKT3
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1 Monoclonal Antibody
Volume : 100 µL
Clone Number :
Aliases : RAC-alpha serine/threonine-protein kinase PKB alpha RAC-PK-alpha proto-oncogene c-Akt protein kinase B alpha rac protein kinase alpha
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P31749
Immunogen : Recombinant fragment of human AKT1 (C-terminus)
Raised in : Mouse
Species Reactivity : Human,Mouse,Pig,Rat
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background :
Clonality : Monoclonal
Isotype : IgG2b
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling;Cancer;Metabolism;Signal transduction
658,94 € 658.94 EUR
AKT1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : Recombinant Human RAC-alpha serine/threonine-protein kinase protein (1-480AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKT1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : Recombinant Human RAC-alpha serine/threonine-protein kinase protein (1-480AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKT1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : Recombinant Human RAC-alpha serine/threonine-protein kinase protein (1-480AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKT1 antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs thro µgh phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1 which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. M µLtiple alternatively spliced transcript variants have been found for this gene.
Immunogen : v-akt murine thymoma viral oncogene homolog 1
Aliases : AKT, AKT1 PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Observed MW : 60 kDa
Uniprot ID : P31749
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 100; IF : 1 : 50 - 1 : 100
Gene ID : 207
Research Area : Metabolism, Cardiovasc µLar, Immunology, Developmental biology, Neuroscience, Stem Cells
310,20 € 310.2 EUR
AKT1 (Ab 473) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : Peptide sequence around aa. 471~475 (Q-F-S-Y-S) derived from Human Akt.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating ins µLin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the ins µLin-induced activation of glycogen synthase.

Baudhuin LM, et al. (2004) FASEB J Feb; 18(2) : 341-3.
Min YH, et al. (2004) Cancer Res; 64(15) : 5225-31.
Feng J, et al. (2004) J Biol Chem; 279(34) : 35510-7.
Ayala G, et al. (2004) Clin Cancer Res; 10(19) : 6572-8.
Lungu AO, et al. (2004) J Biol Chem; 279(47) : 48794-800.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1 (Ab 450) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : Peptide sequence around aa.448~452 (T-I-T-P-P) derived from Human AKT1.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF : 1 : 100-1 : 200
Background : General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating ins µLin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the ins µLin-induced activation of glycogen synthase.

Xing J, et al. (1998) Mol Cell Biol 18(4) : 1946-55.
Tan Y, et al.( 1996) EMBO J; 15(17) : 4629-42.
Hao, M. et al. (1996) J. Biol. Chem. 271 29380-29385.
Mayo LD, et al. (2001) Biol Chem; 276(27) : 25184-9.
Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-5934.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1 (Ab 326) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : SyntheVolumed non-phosphopeptide derived from Human Akt around the phosphorylation site of tyrosine 326 (N-D-Y(p)-G-R).
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 3000, IHC : 1 : 50-1 : 100, IF : 1 : 100-1 : 500
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53. AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation mod µLates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform hasa more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.

Amy D. Sinor, J. Neurosci., Sep 2004; 24 : 8531 - 8541.
Daniela Matei, Clin. Cancer Res., Jan 2004; 10 : 681.
Jesika Faridi, Clin. Cancer Res., A µg 2003; 9 : 2933
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1 (Ab 308) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : Peptide sequence around aa.306~310 (M-K-T-F-C) derived from Human AKT1.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background :
General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating ins µLin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the ins µLin-induced activation of glycogen synthase.

Tremblay F, et al. (2005) Diabetes; 54(9) : 2674-84.
Xu BE, et al. (2005) J Biol Chem; 280(40) : 34218-23.
Samuels Y, et al. (2005) Cancer Cell; 7(6) : 561-73.
Di Maira G, et al. (2005) Cell Death Differ; 12(6) : 668-77.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1 (Ab 129) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : SyntheVolumed non-phosphopeptide derived from Human Akt around the phosphorylation site of serine 129 (D-N-S(p)-G-A).
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 3000, IHC : 1 : 50-1 : 100, IF : 1 : 100-1 : 500
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53. AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation mod µLates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform hasa more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.

Jones P.F., Proc. Natl. Acad. Sci. U.S.A. 88 : 4171-4175(1991).
Matsubara A., Diabetologia 44 : 910-913(2001).
The MGC Project Team; Genome Res. 14 : 2121-2127(2004).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT1 (Ab 124) Antibody
Volume : 100 µL
Clone Number :
Aliases : AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; C AKT antibody; cAKT antibody; MGC99656 antibody; PKB alpha antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; Rac protein kinase alpha antibody; RAC Serine/Threonine Protein Kinase antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody; v akt murine thymoma viral oncogene homolog 1 antibody; vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P31749
Immunogen : SyntheVolumed non-phosphopeptide derived from Human Akt around the phosphorylation site of serine 124 (S-G-S(p)-P-S).
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 3000
Background : AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1 AKT2 and AKT3) called the AKT kinase, and which reg µLate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated thro µgh serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificityhas been reported. AKT is responsible of the reg µLation of glucose uptake by mediating ins µLin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively mod µLates its phosphatase activity preventing dephosphorylation of the ins µLin receptor and the attenuation of ins µLin signaling. Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for ins µLin-stim µLated glucose transport. AKT reg µLates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', res µLting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also tho µght to be one mechanism by which cell proliferation is driven. AKT reg µLates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase). Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stim µLated by oxidative stress and thereby prevents apoptosis. AKT mediates ins µLin-stim µLated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization. In partic µLar, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and FOXO4 are phosphorylated on equivalent sites. AKT has an important role in the reg µLation of NF-kappa-B-dependent gene transcription and positively reg µLates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1. AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially reg µLating ACLY activity and fatty acid synthesis. Activates the 3B isoform ofcyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', res µLting in reduced cyclic AMP levels and inhibition of lipolysis. Phosphorylates PIKFYVE on 'Ser-318', which res µLts in increased PI3P-5 activity. The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the reg µLation cell proliferation and cell growth. AKT plays a role as key mod µLator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during ad µLt neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), ins µLin and ins µLin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I. Essential for the SPATA13-mediated reg µLation of cell migration and adhesion assembly and disassembly. May be involved in the reg µLation of the placental development. Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its : kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its : cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation. Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation. Phosphorylates RAF1 at 'Ser-259' and negatively reg µLates its activity. Phosphorylation of BAD stim µLates its pro-apoptotic activity. Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively reg µLates its acetylation activity towards p53/TP53. AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation mod µLates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform hasa more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.

Payaningal R. Somanath, J. Biol. Chem., Jun 2007; 10.1074.
Xiaoming Ju, PNAS, May 2007; 104 : 7438 - 7443.
Brian DeBosch, Circ µLation, May 2006; 113 : 2097 - 2104
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKT1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Metabolism;Signal transduction
509,65 € 509.65 EUR
AKT antibody
Volume : 100 µg
Purification : Protein A+G purification
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Mouse
Clonality : monoclonal
Clone ID : 8H0
Isotype : IgG1
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1 which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with/without phospho-modification.
Immunogen : v-akt murine thymoma viral oncogene homolog 1
Aliases : AKT, AKT1 AKT2, AKT3, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Observed MW : 56-62 kDa
Uniprot ID : P31749
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF, IP
Recommended dilution : WB : 1 : 1000-1 : 10000; IP : 1 : 500-1 : 5000; IHC : 1 : 100-1 : 400; IF : 1 : 10-1 : 100
Gene ID : 207
Research Area : Metabolism, Cardiovasc µLar, Immunology, Developmental biology, Neuroscience, Stem Cells
353,10 € 353.1 EUR
AKR7A3 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR7A3
GeneID : 22977
Uniprot : O95154
Specificity : AKR7A3 Antibody detects endogenous levels of total AKR7A3.
Immunogen : A syntheVolumed peptide derived from human AKR7A3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845780
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12819-BP
Des# Blocking Peptide : AKR7A3 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR7A2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR7A2
GeneID : 8574
Uniprot : O43488
Specificity : AKR7A2 Antibody detects endogenous levels of total AKR7A2.
Immunogen : A syntheVolumed peptide derived from human AKR7A2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838323
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6359-BP
Des# Blocking Peptide : AKR7A2 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1E2 Antibody
Volume : 50 µg
Clone Number :
Aliases : AKR1E2 antibody; AKR1CL2 antibody; AKRDC115-anhydro-D-fructose reductase antibody; AF reductase antibody; EC 1.1.1.263 antibody; Aldo-keto reductase family 1 member C-like protein 2 antibody; Aldo-keto reductase family 1 member E2 antibody; LoopADR antibody; Testis aldo-keto reductase antibody; htAKR antibody; Testis-specific protein antibody; hTSP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JD6
Immunogen : SyntheVolumed peptide derived from the Internal region of Human AKR1CL2.
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1E2
Research Areas : Cancer;Metabolism;Signal transduction
171,60 € 171.6 EUR
AKR1D1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : 3-oxo-5-beta-steroid 4-dehydrogenase antibody; 3o5bred antibody; AK1D1_HUMAN antibody; AKR1D1 antibody; aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody; Aldo keto reductase family 1 member D1 antibody; Aldo-keto reductase family 1 member D1 antibody; CBAS2 antibody; Delta(4) 3 ketosteroid 5 beta reductase antibody; Delta(4) 3 oxosteroid 5 beta reductase antibody; Delta(4)-3-ketosteroid 5-beta-reductase antibody; Delta(4)-3-oxosteroid 5-beta-reductase antibody; SRD5B1 antibody; steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody; steroid 5 beta reductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51857
Immunogen : Recombinant Human 3-oxo-5-beta-steroid 4-dehydrogenase protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1D1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1D1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 3-oxo-5-beta-steroid 4-dehydrogenase antibody; 3o5bred antibody; AK1D1_HUMAN antibody; AKR1D1 antibody; aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody; Aldo keto reductase family 1 member D1 antibody; Aldo-keto reductase family 1 member D1 antibody; CBAS2 antibody; Delta(4) 3 ketosteroid 5 beta reductase antibody; Delta(4) 3 oxosteroid 5 beta reductase antibody; Delta(4)-3-ketosteroid 5-beta-reductase antibody; Delta(4)-3-oxosteroid 5-beta-reductase antibody; SRD5B1 antibody; steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody; steroid 5 beta reductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51857
Immunogen : Recombinant Human 3-oxo-5-beta-steroid 4-dehydrogenase protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1D1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1D1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 3-oxo-5-beta-steroid 4-dehydrogenase antibody; 3o5bred antibody; AK1D1_HUMAN antibody; AKR1D1 antibody; aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody; Aldo keto reductase family 1 member D1 antibody; Aldo-keto reductase family 1 member D1 antibody; CBAS2 antibody; Delta(4) 3 ketosteroid 5 beta reductase antibody; Delta(4) 3 oxosteroid 5 beta reductase antibody; Delta(4)-3-ketosteroid 5-beta-reductase antibody; Delta(4)-3-oxosteroid 5-beta-reductase antibody; SRD5B1 antibody; steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody; steroid 5 beta reductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51857
Immunogen : Recombinant Human 3-oxo-5-beta-steroid 4-dehydrogenase protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1D1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1D1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1D1
GeneID : 6718
Uniprot : P51857
Specificity : AKR1D1 Antibody detects endogenous levels of AKR1D1.
Immunogen : A syntheVolumed peptide derived from human AKR1D1.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14902-BP
Des# Blocking Peptide : AKR1D1 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1CL2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1E2
GeneID : 83592
Uniprot : Q96JD6
Specificity : AKR1CL2 Antibody detects endogenous levels of total AKR1CL2.
Immunogen : A syntheVolumed peptide derived from human AKR1CL2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836122
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3758-BP
Des# Blocking Peptide : AKR1CL2 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1CL1 Antibody
Volume : 50 µg
Clone Number :
Aliases : AKR1C8P antibody; AKR1CL1Putative aldo-keto reductase family 1 member C8 antibody; Aldo-keto reductase family 1 member C-like protein 1 antibody; EC 1.1.1.- antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T2L2
Immunogen : SyntheVolumed peptide derived from the Internal region of Human AKR1CL1.
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : IF, ELISA; IF : 1 : 200-1 : 1000, ELISA : 1 : 40000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C8P
Research Areas : Others
171,60 € 171.6 EUR
AKR1C4/Aldo keto Reductase 1C4
Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : N-6His
Species : Human
Expressed In : E.coli
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
633,60 € 633.6 EUR
AKR1C4 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1C4
GeneID : 1109
Uniprot : P17516
Specificity : AKR1C4 Antibody detects endogenous levels of total AKR1C4.
Immunogen : A syntheVolumed peptide derived from human AKR1C4, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Rat
Prediction :
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842386
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF9190-BP
Des# Blocking Peptide : AKR1C4 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1C3 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1C3
GeneID : 8644
Uniprot : P42330
Specificity : AKR1C3 Antibody detects endogenous levels of total AKR1C3.
Immunogen : A syntheVolumed peptide derived from human AKR1C3, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838575
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6613-BP
Des# Blocking Peptide : AKR1C3 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1C2/Aldo keto reductase family 1 member C2
Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : None
Species : Human
Expressed In : E.coli
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.
633,60 € 633.6 EUR
AKR1C2 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 3 alpha HSD3 antibody; 3 alpha hydroxysteroid dehydrogenase type III antibody; 3-alpha-HSD3 antibody; AK1C2_HUMAN antibody; AKR1C pseudo antibody; AKR1C2 antibody; Aldo keto reductase family 1 member C2 antibody; Aldo-keto reductase family 1 member C2 antibody; BABP antibody; Bile acid binding protein antibody; Chlordecone reductase homolog antibody; Chlordecone reductase homolog HAKRD antibody; DD antibody; DD-2 antibody; DD/BABP antibody; DD2 antibody; DDH 2 antibody; DDH2 antibody; Dihydrodiol dehydrogenase 2 antibody; Dihydrodiol dehydrogenase/bile acid binding protein antibody; Dihydrodiol dehydrogenase/bile acid-binding protein antibody; FLJ53800 antibody; HAKRD antibody; HBAB antibody; MCDR 2 antibody; MCDR2 antibody; OTTHUMP00000044759 antibody; Pseudo chlordecone reductase antibody; SRXY8 antibody; Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase antibody; Trans-1 antibody; Type II dihydrodiol dehydrogenase antibody; Type III 3 alpha hydroxysteroid dehydrogenase antibody; Type III 3-alpha-hydroxysteroid dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52895
Immunogen : Recombinant Human Aldo-keto reductase family 1 member C2 protein (1-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C2
Research Areas : Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1C2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 3 alpha HSD3 antibody; 3 alpha hydroxysteroid dehydrogenase type III antibody; 3-alpha-HSD3 antibody; AK1C2_HUMAN antibody; AKR1C pseudo antibody; AKR1C2 antibody; Aldo keto reductase family 1 member C2 antibody; Aldo-keto reductase family 1 member C2 antibody; BABP antibody; Bile acid binding protein antibody; Chlordecone reductase homolog antibody; Chlordecone reductase homolog HAKRD antibody; DD antibody; DD-2 antibody; DD/BABP antibody; DD2 antibody; DDH 2 antibody; DDH2 antibody; Dihydrodiol dehydrogenase 2 antibody; Dihydrodiol dehydrogenase/bile acid binding protein antibody; Dihydrodiol dehydrogenase/bile acid-binding protein antibody; FLJ53800 antibody; HAKRD antibody; HBAB antibody; MCDR 2 antibody; MCDR2 antibody; OTTHUMP00000044759 antibody; Pseudo chlordecone reductase antibody; SRXY8 antibody; Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase antibody; Trans-1 antibody; Type II dihydrodiol dehydrogenase antibody; Type III 3 alpha hydroxysteroid dehydrogenase antibody; Type III 3-alpha-hydroxysteroid dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52895
Immunogen : Recombinant Human Aldo-keto reductase family 1 member C2 protein (1-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C2
Research Areas : Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1C2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 3 alpha HSD3 antibody; 3 alpha hydroxysteroid dehydrogenase type III antibody; 3-alpha-HSD3 antibody; AK1C2_HUMAN antibody; AKR1C pseudo antibody; AKR1C2 antibody; Aldo keto reductase family 1 member C2 antibody; Aldo-keto reductase family 1 member C2 antibody; BABP antibody; Bile acid binding protein antibody; Chlordecone reductase homolog antibody; Chlordecone reductase homolog HAKRD antibody; DD antibody; DD-2 antibody; DD/BABP antibody; DD2 antibody; DDH 2 antibody; DDH2 antibody; Dihydrodiol dehydrogenase 2 antibody; Dihydrodiol dehydrogenase/bile acid binding protein antibody; Dihydrodiol dehydrogenase/bile acid-binding protein antibody; FLJ53800 antibody; HAKRD antibody; HBAB antibody; MCDR 2 antibody; MCDR2 antibody; OTTHUMP00000044759 antibody; Pseudo chlordecone reductase antibody; SRXY8 antibody; Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase antibody; Trans-1 antibody; Type II dihydrodiol dehydrogenase antibody; Type III 3 alpha hydroxysteroid dehydrogenase antibody; Type III 3-alpha-hydroxysteroid dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52895
Immunogen : Recombinant Human Aldo-keto reductase family 1 member C2 protein (1-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C2
Research Areas : Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1C2 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1C2
GeneID : 1646
Uniprot : P52895
Specificity : AKR1C2 Antibody detects endogenous levels of total AKR1C2.
Immunogen : A syntheVolumed peptide derived from human AKR1C2, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836121
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3757-BP
Des# Blocking Peptide : AKR1C2 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1C1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody; 20 ALPHA HSD antibody; 20 alpha hydroxysteroid dehydrogenase antibody; 20-alpha-HSD antibody; 20-alpha-hydroxysteroid dehydrogenase antibody; 20ALPHAHSD antibody; 2ALPHAHSD antibody; AK1C1 antibody; AK1C1_HUMAN antibody; AKR1C1 antibody; Aldo keto reductase family 1 member C1 antibody; aldo-keto reductase C antibody; Aldo-keto reductase family 1 member C1 antibody; Aldo-keto reductase family; 1 member 1 antibody; C9 antibody; Chlordecone reductase homolog antibody; Chlordecone reductase homolog HAKRC antibody; DD1 antibody; DD1/DD2 antibody; DDH antibody; DDH1 antibody; Dihydrodiol dehydrogenase 1 antibody; Dihydrodiol dehydrogenase 1/2 antibody; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase antibody; dihydrodiol dehydrogenase isoform DD1 antibody; Dihydrodiol dehydrogenase; type 1 antibody; H37 antibody; HAKRC antibody; HBAB antibody; Hepatic dihydrodiol dehydrogenase antibody; High affinity hepatic bile acid-binding protein antibody; High-affinity hepatic bile acid-binding protein antibody; Indanol dehydrogenase antibody; MBAB antibody; MGC8954 antibody; Trans-1 antibody; Trans-12 dihydrobenzene 12 diol dehydrogenase antibody; Type II 3 alpha hydroxysteroid dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q04828
Immunogen : Recombinant Human Aldo-keto reductase family 1 member C1 protein (219-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C1
Research Areas : Cancer; Developmental biology; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1C1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody; 20 ALPHA HSD antibody; 20 alpha hydroxysteroid dehydrogenase antibody; 20-alpha-HSD antibody; 20-alpha-hydroxysteroid dehydrogenase antibody; 20ALPHAHSD antibody; 2ALPHAHSD antibody; AK1C1 antibody; AK1C1_HUMAN antibody; AKR1C1 antibody; Aldo keto reductase family 1 member C1 antibody; aldo-keto reductase C antibody; Aldo-keto reductase family 1 member C1 antibody; Aldo-keto reductase family; 1 member 1 antibody; C9 antibody; Chlordecone reductase homolog antibody; Chlordecone reductase homolog HAKRC antibody; DD1 antibody; DD1/DD2 antibody; DDH antibody; DDH1 antibody; Dihydrodiol dehydrogenase 1 antibody; Dihydrodiol dehydrogenase 1/2 antibody; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase antibody; dihydrodiol dehydrogenase isoform DD1 antibody; Dihydrodiol dehydrogenase; type 1 antibody; H37 antibody; HAKRC antibody; HBAB antibody; Hepatic dihydrodiol dehydrogenase antibody; High affinity hepatic bile acid-binding protein antibody; High-affinity hepatic bile acid-binding protein antibody; Indanol dehydrogenase antibody; MBAB antibody; MGC8954 antibody; Trans-1 antibody; Trans-12 dihydrobenzene 12 diol dehydrogenase antibody; Type II 3 alpha hydroxysteroid dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q04828
Immunogen : Recombinant Human Aldo-keto reductase family 1 member C1 protein (219-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C1
Research Areas : Cancer; Developmental biology; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1C1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody; 20 ALPHA HSD antibody; 20 alpha hydroxysteroid dehydrogenase antibody; 20-alpha-HSD antibody; 20-alpha-hydroxysteroid dehydrogenase antibody; 20ALPHAHSD antibody; 2ALPHAHSD antibody; AK1C1 antibody; AK1C1_HUMAN antibody; AKR1C1 antibody; Aldo keto reductase family 1 member C1 antibody; aldo-keto reductase C antibody; Aldo-keto reductase family 1 member C1 antibody; Aldo-keto reductase family; 1 member 1 antibody; C9 antibody; Chlordecone reductase homolog antibody; Chlordecone reductase homolog HAKRC antibody; DD1 antibody; DD1/DD2 antibody; DDH antibody; DDH1 antibody; Dihydrodiol dehydrogenase 1 antibody; Dihydrodiol dehydrogenase 1/2 antibody; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase antibody; dihydrodiol dehydrogenase isoform DD1 antibody; Dihydrodiol dehydrogenase; type 1 antibody; H37 antibody; HAKRC antibody; HBAB antibody; Hepatic dihydrodiol dehydrogenase antibody; High affinity hepatic bile acid-binding protein antibody; High-affinity hepatic bile acid-binding protein antibody; Indanol dehydrogenase antibody; MBAB antibody; MGC8954 antibody; Trans-1 antibody; Trans-12 dihydrobenzene 12 diol dehydrogenase antibody; Type II 3 alpha hydroxysteroid dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q04828
Immunogen : Recombinant Human Aldo-keto reductase family 1 member C1 protein (219-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1C1
Research Areas : Cancer; Developmental biology; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1C1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1C1
GeneID : 1645
Uniprot : Q04828
Specificity : AKR1C1 Antibody detects endogenous levels of total AKR1C1.
Immunogen : A syntheVolumed peptide derived from human AKR1C1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Monkey
Prediction :
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842385
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF9189-BP
Des# Blocking Peptide : AKR1C1 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1B10 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1B10
GeneID : 57016
Uniprot : O60218
Specificity : AKR1B10 Antibody detects endogenous levels of total AKR1B10.
Immunogen : A syntheVolumed peptide derived from human AKR1B10, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2846424
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13405-BP
Des# Blocking Peptide : AKR1B10 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1B1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : ADR antibody; AKR1B 1 antibody; Akr1b1 antibody; Aldehyde reductase 1 antibody; Aldehyde reductase antibody; Aldo keto reductase family 1; member B1 antibody; Aldo-keto reductase family 1 member B1 antibody; aldo-keto reductase family 1; member B1 (aldose reductase) antibody; Aldose reductase antibody; aldr 1 antibody; ALDR_HUMAN antibody; aldr1 antibody; ALR2 antibody; AR antibody; Lii5 2 CTCL tumor antigen antibody; Low Km aldose reductase antibody; MGC1804 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15121
Immunogen : Recombinant Human Aldose reductase protein (114-230AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1B1
Research Areas : Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1B1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : ADR antibody; AKR1B 1 antibody; Akr1b1 antibody; Aldehyde reductase 1 antibody; Aldehyde reductase antibody; Aldo keto reductase family 1; member B1 antibody; Aldo-keto reductase family 1 member B1 antibody; aldo-keto reductase family 1; member B1 (aldose reductase) antibody; Aldose reductase antibody; aldr 1 antibody; ALDR_HUMAN antibody; aldr1 antibody; ALR2 antibody; AR antibody; Lii5 2 CTCL tumor antigen antibody; Low Km aldose reductase antibody; MGC1804 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15121
Immunogen : Recombinant Human Aldose reductase protein (114-230AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1B1
Research Areas : Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1B1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : ADR antibody; AKR1B 1 antibody; Akr1b1 antibody; Aldehyde reductase 1 antibody; Aldehyde reductase antibody; Aldo keto reductase family 1; member B1 antibody; Aldo-keto reductase family 1 member B1 antibody; aldo-keto reductase family 1; member B1 (aldose reductase) antibody; Aldose reductase antibody; aldr 1 antibody; ALDR_HUMAN antibody; aldr1 antibody; ALR2 antibody; AR antibody; Lii5 2 CTCL tumor antigen antibody; Low Km aldose reductase antibody; MGC1804 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15121
Immunogen : Recombinant Human Aldose reductase protein (114-230AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1B1
Research Areas : Cancer; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1B1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1B1
GeneID : 231
Uniprot : P15121
Specificity : AKR1B1 Antibody detects endogenous levels of total AKR1B1.
Immunogen : A syntheVolumed peptide derived from human AKR1B1 corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836123
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3759-BP
Des# Blocking Peptide : AKR1B1 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKR1A1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : AK1A1_HUMAN antibody; Akr1a1 antibody; Alcohol dehydrogenase [NADP+] antibody; Alcohol dehydrogenase antibody; Aldehyde reductase antibody; Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody; Aldo-keto reductase family 1 member A1 antibody; ALDR1 antibody; ALR antibody; ARM antibody; DD3 antibody; MGC12529 antibody; MGC1380 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P14550
Immunogen : Recombinant Human Alcohol dehydrogenase [NADP(+)] protein (2-325AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 12-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and dr µgs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1A1
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1A1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : AK1A1_HUMAN antibody; Akr1a1 antibody; Alcohol dehydrogenase [NADP+] antibody; Alcohol dehydrogenase antibody; Aldehyde reductase antibody; Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody; Aldo-keto reductase family 1 member A1 antibody; ALDR1 antibody; ALR antibody; ARM antibody; DD3 antibody; MGC12529 antibody; MGC1380 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P14550
Immunogen : Recombinant Human Alcohol dehydrogenase [NADP(+)] protein (2-325AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 12-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and dr µgs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1A1
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1A1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AK1A1_HUMAN antibody; Akr1a1 antibody; Alcohol dehydrogenase [NADP+] antibody; Alcohol dehydrogenase antibody; Aldehyde reductase antibody; Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody; Aldo-keto reductase family 1 member A1 antibody; ALDR1 antibody; ALR antibody; ARM antibody; DD3 antibody; MGC12529 antibody; MGC1380 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P14550
Immunogen : Recombinant Human Alcohol dehydrogenase [NADP(+)] protein (2-325AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 12-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and dr µgs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AKR1A1
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction
2.848,56 € 2848.56 EUR
AKR1A1 Antibody
Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : AKR1A1
GeneID : 10327
Uniprot : P14550
Specificity : AKR1A1 Antibody detects endogenous levels of total AKR1A1.
Immunogen : A syntheVolumed peptide derived from human AKR1A1 corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836116
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3752-BP
Des# Blocking Peptide : AKR1A1 Blocking peptide
Blocking Peptide Price : $549 CAD
336,60 € 336.6 EUR
AKNA antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately reg µLates expression of the CD40 receptor and its ligand (CD154), two molec µLes that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID : 15869410)
Immunogen : AT-hook transcription factor
Aliases : AKNA, AT hook transcription factor, FLJ31001 FLJ33184, KIAA1968, RP11 82I1.4
Observed MW : 65-70 kDa
Uniprot ID : Q7Z591
Reactivity : Human
Application : ELISA, IHC, WB
Recommended dilution : WB : 1 : 200-1 : 2000; IF : 1 : 20-200
Gene ID : 80709
Research Area : Metabolism
310,20 € 310.2 EUR