Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed : 22582013, PubMed : 23754375, PubMed : 25789606). Constitutes the main protein kinase for extracell µLar proteins, generating the majority of the extracell µLar phosphoproteome(PubMed : 26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed : 26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed : 22582013, PubMed : 25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed : 26091039).
Immunogen : family with sequence similarity 20, member C
Aliases : Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS
Observed MW : 50 kDa
Uniprot ID : Q8IXL6
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200
Gene ID : 56975
Research Area : Cell Division and Proliferation