Volume : 100 µL
Clone Number :
Aliases : CDK 6 antibody; CDK6 antibody; CDK6_HUMAN antibody; Cell division protein kinase 6 antibody; Crk 2 antibody; Crk2 antibody; Cyclin dependent kinase 6 antibody; Cyclin-dependent kinase 6 antibody; MCPH12 antibody; MGC59692 antibody; p40 antibody; PLSTIRE antibody; Serine/threonine protein kinase PLSTIRE antibody; Serine/threonine-protein kinase PLSTIRE antibody; STQTL11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00534
Immunogen : Peptide sequence around aa.22~26 (G-A-Y-G-K) derived from Human CDK6.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK6
Research Areas : Epigenetics and Nuclear Signaling;Cancer;Cell biology

Volume : 100 µL
Clone Number :
Aliases : CDK 6 antibody; CDK6 antibody; CDK6_HUMAN antibody; Cell division protein kinase 6 antibody; Crk 2 antibody; Crk2 antibody; Cyclin dependent kinase 6 antibody; Cyclin-dependent kinase 6 antibody; MCPH12 antibody; MGC59692 antibody; p40 antibody; PLSTIRE antibody; Serine/threonine protein kinase PLSTIRE antibody; Serine/threonine-protein kinase PLSTIRE antibody; STQTL11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00534
Immunogen : Peptide sequence around aa.11~15 (Q-Q-Y-E-C) derived from Human CDK6.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, IHC, IF; IHC : 1 : 50-1 : 100, IF : 1 : 100-1 : 200
Background : Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK6
Research Areas : Epigenetics and Nuclear Signaling;Cancer;Cell biology

Volume : 50 µL
Clone Number :
Aliases : C53 antibody; CDK5 activator binding protein C53 antibody; CDK5 activator-binding protein C53 antibody; CDK5 reg µLatory subunit associated protein 3 antibody; CDK5 reg µLatory subunit-associated protein 3 antibody; Cdk5rap3 antibody; CK5P3_HUMAN antibody; HSF 27 antibody; HSF27 antibody; IC53 antibody; Ischemic heart CDK5 activator binding protein C53 antibody; LXXLL/leucine zipper containing ARFbinding protein antibody; LZAP antibody; MST016 antibody; OK/SW cl.114 antibody; PP1553 antibody; Protein HSF-27 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JB5
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 3 protein (42-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed : 12054757, PubMed : 12737517). Negatively reg µLates NF-kappa-B-mediated gene transcription thro µgh the control of RELA phosphorylation (PubMed : 17785205, PubMed : 20228063). Also reg µLates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed : 15790566, PubMed : 19223857). Thro µgh its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed : 16173922). May play a role in the unfolded protein response, mediating the ufmylation of m µLtiple proteins in response to endoplasmic retic µLum stress (PubMed : 23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed : 23478299). May reg µLate MAPK14 activity by reg µLating its dephosphorylation by PPM1D/WIP1 (PubMed : 21283629).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP3
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : C53 antibody; CDK5 activator binding protein C53 antibody; CDK5 activator-binding protein C53 antibody; CDK5 reg µLatory subunit associated protein 3 antibody; CDK5 reg µLatory subunit-associated protein 3 antibody; Cdk5rap3 antibody; CK5P3_HUMAN antibody; HSF 27 antibody; HSF27 antibody; IC53 antibody; Ischemic heart CDK5 activator binding protein C53 antibody; LXXLL/leucine zipper containing ARFbinding protein antibody; LZAP antibody; MST016 antibody; OK/SW cl.114 antibody; PP1553 antibody; Protein HSF-27 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JB5
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 3 protein (42-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed : 12054757, PubMed : 12737517). Negatively reg µLates NF-kappa-B-mediated gene transcription thro µgh the control of RELA phosphorylation (PubMed : 17785205, PubMed : 20228063). Also reg µLates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed : 15790566, PubMed : 19223857). Thro µgh its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed : 16173922). May play a role in the unfolded protein response, mediating the ufmylation of m µLtiple proteins in response to endoplasmic retic µLum stress (PubMed : 23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed : 23478299). May reg µLate MAPK14 activity by reg µLating its dephosphorylation by PPM1D/WIP1 (PubMed : 21283629).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP3
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : C53 antibody; CDK5 activator binding protein C53 antibody; CDK5 activator-binding protein C53 antibody; CDK5 reg µLatory subunit associated protein 3 antibody; CDK5 reg µLatory subunit-associated protein 3 antibody; Cdk5rap3 antibody; CK5P3_HUMAN antibody; HSF 27 antibody; HSF27 antibody; IC53 antibody; Ischemic heart CDK5 activator binding protein C53 antibody; LXXLL/leucine zipper containing ARFbinding protein antibody; LZAP antibody; MST016 antibody; OK/SW cl.114 antibody; PP1553 antibody; Protein HSF-27 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JB5
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 3 protein (42-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed : 12054757, PubMed : 12737517). Negatively reg µLates NF-kappa-B-mediated gene transcription thro µgh the control of RELA phosphorylation (PubMed : 17785205, PubMed : 20228063). Also reg µLates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed : 15790566, PubMed : 19223857). Thro µgh its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed : 16173922). May play a role in the unfolded protein response, mediating the ufmylation of m µLtiple proteins in response to endoplasmic retic µLum stress (PubMed : 23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed : 23478299). May reg µLate MAPK14 activity by reg µLating its dephosphorylation by PPM1D/WIP1 (PubMed : 21283629).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP3
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK5RAP3
GeneID : 80279
Uniprot : Q96JB5
Specificity : CDK5RAP3 Antibody detects endogenous levels of total CDK5RAP3.
Immunogen : A syntheVolumed peptide derived from human CDK5RAP3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat,Monkey
Prediction :
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835920
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3547-BP
Des# Blocking Peptide : CDK5RAP3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : C48 antibody; CDK5 activator-binding protein C48 antibody; CDK5 reg µLatory subunit associated protein 2 antibody; CDK5 reg µLatory subunit-associated protein 2 antibody; CDK5RAP2 antibody; centrosomal protein 215 kDa antibody; Centrosome-associated protein 215 antibody; CEP215 antibody; CK5P2_HUMAN antibody; MCPH3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96SN8
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 2 protein (996-1111AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Potential reg µLator of CDK5 activity via its interaction with CDK5R1. Negative reg µLator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in reg µLation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional reg µLator of both BUBR1 and MAD2 promoter. Together with MAPRE1 it may promote microtub µLe polymerization, bundle formation, growth and dynamics at the plus ends. Reg µLates centrosomal maturation by recruitment of a gamma-tub µLin ring complex onto centrosomes (PubMed : 26485573).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C48 antibody; CDK5 activator-binding protein C48 antibody; CDK5 reg µLatory subunit associated protein 2 antibody; CDK5 reg µLatory subunit-associated protein 2 antibody; CDK5RAP2 antibody; centrosomal protein 215 kDa antibody; Centrosome-associated protein 215 antibody; CEP215 antibody; CK5P2_HUMAN antibody; MCPH3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96SN8
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 2 protein (996-1111AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Potential reg µLator of CDK5 activity via its interaction with CDK5R1. Negative reg µLator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in reg µLation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional reg µLator of both BUBR1 and MAD2 promoter. Together with MAPRE1 it may promote microtub µLe polymerization, bundle formation, growth and dynamics at the plus ends. Reg µLates centrosomal maturation by recruitment of a gamma-tub µLin ring complex onto centrosomes (PubMed : 26485573).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C48 antibody; CDK5 activator-binding protein C48 antibody; CDK5 reg µLatory subunit associated protein 2 antibody; CDK5 reg µLatory subunit-associated protein 2 antibody; CDK5RAP2 antibody; centrosomal protein 215 kDa antibody; Centrosome-associated protein 215 antibody; CEP215 antibody; CK5P2_HUMAN antibody; MCPH3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96SN8
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 2 protein (996-1111AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Potential reg µLator of CDK5 activity via its interaction with CDK5R1. Negative reg µLator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in reg µLation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional reg µLator of both BUBR1 and MAD2 promoter. Together with MAPRE1 it may promote microtub µLe polymerization, bundle formation, growth and dynamics at the plus ends. Reg µLates centrosomal maturation by recruitment of a gamma-tub µLin ring complex onto centrosomes (PubMed : 26485573).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology; Tags & Cell Markers; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK5RAP2
GeneID : 55755
Uniprot : Q96SN8
Specificity : CDK5RAP2 Antibody detects endogenous levels of CDK5RAP2.
Immunogen : A syntheVolumed peptide derived from human CDK5RAP2.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15707-BP
Des# Blocking Peptide : CDK5RAP2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK5RAP1
GeneID : 51654
Uniprot : Q96SZ6
Specificity : CDK5RAP1 Antibody detects endogenous levels of total CDK5RAP1.
Immunogen : A syntheVolumed peptide derived from human CDK5RAP1 corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842111
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8915-BP
Des# Blocking Peptide : CDK5RAP1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK5R2
GeneID : 8941
Uniprot : Q13319
Specificity : CDK5R2 Antibody detects endogenous levels of total CDK5R2.
Immunogen : A syntheVolumed peptide derived from human CDK5R2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841512
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8204-BP
Des# Blocking Peptide : CDK5R2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK5R1
GeneID : 8851
Uniprot : Q15078
Specificity : CDK5R1/P35 Antibody detects endogenous levels of total CDK5R1/P35.
Immunogen : A syntheVolumed peptide derived from human CDK5R1/P35, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835652
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3284-BP
Des# Blocking Peptide : CDK5R1/P35 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CD5R1_HUMAN antibody; CDK5 activator 1 antibody; CDK5P35 antibody; CDK5R antibody; CDK5R1 antibody; Cyclin dependent kinase 5 reg µLatory subunit 1 antibody; Cyclin-dependent kinase 5 activator 1 antibody; Cyclin-dependent kinase 5 reg µLatory subunit 1 antibody; NCK 5A antibody; Neuronal CDK5 activator antibody; p23 antibody; p25 antibody; p35 antibody; Reg µLatory partner for CDK5 kinase antibody; Tau protein kinase II 23 kDa subunit antibody; TPKII reg µLatory subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15078
Immunogen : SyntheVolumed peptide derived from the N-terminal region of Human p35.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, IF, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, IF : 1 : 200-1 : 1000, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5R1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience;Cell biology;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : cyclin-dependent kinase 5 TPKII catalytic subunit protein kinase CDK5 splicing cell division protein kinase 5 serine/threonine-protein kinase PSSALRE tau protein kinase II catalytic subunit
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : Q00535
Immunogen : Recombinant fragment, corresponding to amino acids 1-138aaof human CDK5(N-terminus).
Raised in : Mouse
Species Reactivity : Human,Mouse,Rat,Pig,Dog
Tested Applications : ELISA,WB,ICC;Recommended dilution : WB : 1 : 500-1 : 5000,ICC : 1 : 50-1 : 200
Background :
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5
Research Areas : Neuroscience?Cancer;Cell biology;Metabolism

Volume : 50 µg
Clone Number :
Aliases : Cdk 5 antibody; Cdk5 antibody; CDK5_HUMAN antibody; Cell division protein kinase 5 antibody; Crk6 antibody; Cyclin dependent kinase 5 antibody; Cyclin-dependent kinase 5 antibody; Protein kinase CDK5 splicing antibody; PSSALRE antibody; Serine threonine protein kinase PSSALRE antibody; Serine/threonine-protein kinase PSSALRE antibody; Tau protein kinase II catalytic subunit antibody; TPKII catalytic subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00535
Immunogen : Recombinant Human Cyclin-dependent-like kinase 5 protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1 MEF2A, SIPA1L1 SH3GLB1 PXN, PAK1 MCAM/MUC18, SEPT5, SYN1 DNM1 AMPH, SYNJ1 CDK16, RAC1 RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1 p53/TP53, HDAC1 APEX1 PTK2/FAK1 huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Reg µLates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in post-mitotic neurons, and promotes CDK5R1 (p35) expression in an autostim µLation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1 RAC1 RHOA, CDC42) or microtub µLe-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and mod µLates actin dynamics to reg µLate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1 and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1 AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), reg µLates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively reg µLating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus reg µLating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by dereg µLating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative reg µLator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional reg µLon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, res µLting in accum µLation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down reg µLates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May reg µLate endothelial cell migration and angiogenesis via the mod µLation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the reg µLation of the circadian clock by mod µLating the function of CLOCK protein : phosphorylates CLOCK at \\\'Thr-451\\\' and \\\'Thr-461\\\' and reg µLates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcell µLar distribution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Cdk 5 antibody; Cdk5 antibody; CDK5_HUMAN antibody; Cell division protein kinase 5 antibody; Crk6 antibody; Cyclin dependent kinase 5 antibody; Cyclin-dependent kinase 5 antibody; Protein kinase CDK5 splicing antibody; PSSALRE antibody; Serine threonine protein kinase PSSALRE antibody; Serine/threonine-protein kinase PSSALRE antibody; Tau protein kinase II catalytic subunit antibody; TPKII catalytic subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00535
Immunogen : Recombinant Human Cyclin-dependent-like kinase 5 protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1 MEF2A, SIPA1L1 SH3GLB1 PXN, PAK1 MCAM/MUC18, SEPT5, SYN1 DNM1 AMPH, SYNJ1 CDK16, RAC1 RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1 p53/TP53, HDAC1 APEX1 PTK2/FAK1 huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Reg µLates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in post-mitotic neurons, and promotes CDK5R1 (p35) expression in an autostim µLation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1 RAC1 RHOA, CDC42) or microtub µLe-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and mod µLates actin dynamics to reg µLate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1 and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1 AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), reg µLates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively reg µLating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus reg µLating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by dereg µLating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative reg µLator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional reg µLon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, res µLting in accum µLation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down reg µLates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May reg µLate endothelial cell migration and angiogenesis via the mod µLation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the reg µLation of the circadian clock by mod µLating the function of CLOCK protein : phosphorylates CLOCK at \\\'Thr-451\\\' and \\\'Thr-461\\\' and reg µLates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcell µLar distribution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Cdk 5 antibody; Cdk5 antibody; CDK5_HUMAN antibody; Cell division protein kinase 5 antibody; Crk6 antibody; Cyclin dependent kinase 5 antibody; Cyclin-dependent kinase 5 antibody; Protein kinase CDK5 splicing antibody; PSSALRE antibody; Serine threonine protein kinase PSSALRE antibody; Serine/threonine-protein kinase PSSALRE antibody; Tau protein kinase II catalytic subunit antibody; TPKII catalytic subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00535
Immunogen : Recombinant Human Cyclin-dependent-like kinase 5 protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1 MEF2A, SIPA1L1 SH3GLB1 PXN, PAK1 MCAM/MUC18, SEPT5, SYN1 DNM1 AMPH, SYNJ1 CDK16, RAC1 RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1 p53/TP53, HDAC1 APEX1 PTK2/FAK1 huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Reg µLates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in post-mitotic neurons, and promotes CDK5R1 (p35) expression in an autostim µLation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1 RAC1 RHOA, CDC42) or microtub µLe-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and mod µLates actin dynamics to reg µLate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1 and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1 AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), reg µLates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively reg µLating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus reg µLating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by dereg µLating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative reg µLator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional reg µLon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, res µLting in accum µLation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down reg µLates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May reg µLate endothelial cell migration and angiogenesis via the mod µLation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the reg µLation of the circadian clock by mod µLating the function of CLOCK protein : phosphorylates CLOCK at \\\'Thr-451\\\' and \\\'Thr-461\\\' and reg µLates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcell µLar distribution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK5
GeneID : 1020
Uniprot : Q00535
Specificity : CDK5 Antibody detects endogenous levels of total CDK5.
Immunogen : A syntheVolumed peptide derived from human CDK5, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat,Monkey
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835215
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF6371-BP
Des# Blocking Peptide : CDK5 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Clone Number :
Aliases : Cdk 5 antibody; Cdk5 antibody; CDK5_HUMAN antibody; Cell division protein kinase 5 antibody; Crk6 antibody; Cyclin dependent kinase 5 antibody; Cyclin-dependent kinase 5 antibody; Protein kinase CDK5 splicing antibody; PSSALRE antibody; Serine threonine protein kinase PSSALRE antibody; Serine/threonine-protein kinase PSSALRE antibody; Tau protein kinase II catalytic subunit antibody; TPKII catalytic subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00535
Immunogen : SyntheVolumed non-phosphopeptide derived from Human CDK5 around the phosphorylation site of tyrosine 15 (G-T-Y(p)-G-T).
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 3000, IHC : 1 : 50-1 : 100
Background : Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1 MEF2A, SIPA1L1 SH3GLB1 PXN, PAK1 MCAM/MUC18, SEPT5, SYN1 DNM1 AMPH, SYNJ1 CDK16, RAC1 RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1 p53/TP53, HDAC1 APEX1 PTK2/FAK1 huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Reg µLates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in post-mitotic neurons, and promotes CDK5R1 (p35) expression in an autostim µLation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1 RAC1 RHOA, CDC42) or microtub µLe-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and mod µLates actin dynamics to reg µLate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1 and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1 AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), reg µLates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively reg µLating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus reg µLating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by dereg µLating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative reg µLator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional reg µLon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, res µLting in accum µLation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down reg µLates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May reg µLate endothelial cell migration and angiogenesis via the mod µLation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the reg µLation of the circadian clock by mod µLating the function of CLOCK protein : phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and reg µLates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcell µLar distribution.

Meyerson M., EMBO J. 11 : 2909-2917(1992).
Meyerson M.; Submitted (FEB-1993) to the EMBL/GenBank/DDBJ databases.
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5
Research Areas : Neuroscience?Cancer;Cell biology;Metabolism

Volume : 100 µL
Clone Number :
Aliases : cyclin-dependent kinase 4 cell division protein kinase 4
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P11802
Immunogen : Recombinant fragment, corresponding to amino acids 2-151aa of human CDK4(N-terminus).
Raised in : Mouse
Species Reactivity : Human,Rabbit,Pig,Dog,Rat,Mouse
Tested Applications : ELISA,WB,ICC;Recommended dilution : WB : 1 : 500-1 : 5000,ICC : 1 : 50-1 : 200
Background :
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK4
Research Areas : Isotype/Loading Controls;Epigenetics and Nuclear Signaling;Cancer;Cell biology

Volume : 50 µg
Clone Number :
Aliases : Cdk 4 antibody; cdk4 antibody; CDK4 protein antibody; CDK4_HUMAN antibody; Cell division kinase 4 antibody; Cell division protein kinase 4 antibody; CMM 3 antibody; CMM3 antibody; Crk3 antibody; Cyclin dependent kinase 4 antibody; Cyclin-dependent kinase 4 antibody; Melanoma cutaneous malignant 3 antibody; MGC14458 antibody; p34 cdk4 antibody; PSK J3 antibody; PSK-J3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11802
Immunogen : Recombinant Human Cyclin-dependent kinase 4 protein (2-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and reg µLate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression thro µgh the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK4
Research Areas : Isotype/Loading Controls; Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Cdk 4 antibody; cdk4 antibody; CDK4 protein antibody; CDK4_HUMAN antibody; Cell division kinase 4 antibody; Cell division protein kinase 4 antibody; CMM 3 antibody; CMM3 antibody; Crk3 antibody; Cyclin dependent kinase 4 antibody; Cyclin-dependent kinase 4 antibody; Melanoma cutaneous malignant 3 antibody; MGC14458 antibody; p34 cdk4 antibody; PSK J3 antibody; PSK-J3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11802
Immunogen : Recombinant Human Cyclin-dependent kinase 4 protein (2-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and reg µLate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression thro µgh the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK4
Research Areas : Isotype/Loading Controls; Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Cdk 4 antibody; cdk4 antibody; CDK4 protein antibody; CDK4_HUMAN antibody; Cell division kinase 4 antibody; Cell division protein kinase 4 antibody; CMM 3 antibody; CMM3 antibody; Crk3 antibody; Cyclin dependent kinase 4 antibody; Cyclin-dependent kinase 4 antibody; Melanoma cutaneous malignant 3 antibody; MGC14458 antibody; p34 cdk4 antibody; PSK J3 antibody; PSK-J3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11802
Immunogen : Recombinant Human Cyclin-dependent kinase 4 protein (2-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and reg µLate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression thro µgh the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK4
Research Areas : Isotype/Loading Controls; Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK4
GeneID : 1019
Uniprot : P11802
Specificity : CDK4 Antibody detects endogenous levels of total CDK4.
Immunogen : A syntheVolumed peptide derived from human CDK4, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838070
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6102-BP
Des# Blocking Peptide : CDK4 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Cdk 3 antibody; Cdk3 antibody; CDK3_HUMAN antibody; CDKN3 antibody; Cell division kinase 3 antibody; Cell division protein kinase 3 antibody; Cyclin dependent kinase 3 antibody; Cyclin-dependent kinase 3 antibody; OTTHUMP00000206828 antibody; p36 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00526
Immunogen : Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1 ATF1 RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1 E2F2 and E2F3 in a RB1-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cdk 3 antibody; Cdk3 antibody; CDK3_HUMAN antibody; CDKN3 antibody; Cell division kinase 3 antibody; Cell division protein kinase 3 antibody; Cyclin dependent kinase 3 antibody; Cyclin-dependent kinase 3 antibody; OTTHUMP00000206828 antibody; p36 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00526
Immunogen : Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1 ATF1 RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1 E2F2 and E2F3 in a RB1-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cdk 3 antibody; Cdk3 antibody; CDK3_HUMAN antibody; CDKN3 antibody; Cell division kinase 3 antibody; Cell division protein kinase 3 antibody; Cyclin dependent kinase 3 antibody; Cyclin-dependent kinase 3 antibody; OTTHUMP00000206828 antibody; p36 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00526
Immunogen : Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1 ATF1 RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1 E2F2 and E2F3 in a RB1-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK3
GeneID : 1018
Uniprot : Q00526
Specificity : CDK3 Antibody detects endogenous levels of total CDK3.
Immunogen : A syntheVolumed peptide derived from human CDK3, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Sheep,Rabbit
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842107
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8911-BP
Des# Blocking Peptide : CDK3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 50 µg
Clone Number :
Aliases : CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75956
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75956
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75956
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75956
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDK2 A1 antibody; CDK2 associated protein 1 antibody; CDK2-associated protein 1 antibody; CDK2AP1 antibody; CDKA1 antibody; CDKA1_HUMAN antibody; Cyclin dependent kinase 2 associated protein 1 antibody; Cyclin-dependent kinase 2-associated protein 1 antibody; Deleted in oral cancer 1 antibody; DOC 1 antibody; DOC 1 related protein antibody; DOC 1R antibody; DOC-1 antibody; DOC1 antibody; DOC1R antibody; DORC1 antibody; p12DOC 1 antibody; Putative oral cancer suppressor antibody; ST19 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14519
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 1 protein (1-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : specific inhibitor of the cell-cycle kinase CDK2
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CDK2 A1 antibody; CDK2 associated protein 1 antibody; CDK2-associated protein 1 antibody; CDK2AP1 antibody; CDKA1 antibody; CDKA1_HUMAN antibody; Cyclin dependent kinase 2 associated protein 1 antibody; Cyclin-dependent kinase 2-associated protein 1 antibody; Deleted in oral cancer 1 antibody; DOC 1 antibody; DOC 1 related protein antibody; DOC 1R antibody; DOC-1 antibody; DOC1 antibody; DOC1R antibody; DORC1 antibody; p12DOC 1 antibody; Putative oral cancer suppressor antibody; ST19 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14519
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 1 protein (1-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : specific inhibitor of the cell-cycle kinase CDK2
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CDK2 A1 antibody; CDK2 associated protein 1 antibody; CDK2-associated protein 1 antibody; CDK2AP1 antibody; CDKA1 antibody; CDKA1_HUMAN antibody; Cyclin dependent kinase 2 associated protein 1 antibody; Cyclin-dependent kinase 2-associated protein 1 antibody; Deleted in oral cancer 1 antibody; DOC 1 antibody; DOC 1 related protein antibody; DOC 1R antibody; DOC-1 antibody; DOC1 antibody; DOC1R antibody; DORC1 antibody; p12DOC 1 antibody; Putative oral cancer suppressor antibody; ST19 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14519
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 1 protein (1-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : specific inhibitor of the cell-cycle kinase CDK2
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : specific inhibitor of the cell-cycle kinase CDK2.
Immunogen : cyclin-dependent kinase 2 associated protein 1
Aliases : CDKAP1 DOC1
Observed MW : 12 kDa
Uniprot ID : O14519
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 8099
Research Area : Cancer, Signal Transduction, Metabolism

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK20
GeneID : 23552
Uniprot : Q8IZL9
Specificity : CDK20 Antibody detects endogenous levels of total CDK20.
Immunogen : A syntheVolumed peptide derived from human CDK20, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
Application : WB,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2843897
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF7533-BP
Des# Blocking Peptide : CDK20 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : N-6His
Species : Human
Expressed In : E.coli
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 50 µg
Clone Number :
Aliases : Cdc2 related protein kinase antibody; cdc2-related protein kinase antibody; CDC28 antibody; CDC2A antibody; Cdk 2 antibody; CDK1 antibody; CDK2 antibody; CDK2_HUMAN antibody; CDKN2 antibody; Cell devision kinase 2 antibody; Cell division protein kinase 2 antibody; Cyclin dependent kinase 2 antibody; cyclin dependent kinase 2-alpha antibody; Cyclin-dependent kinase 2 antibody; kinase Cdc2 antibody; MPF antibody; p33 protein kinase antibody; p33(CDK2) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24941
Immunogen : Recombinant Human Cyclin-dependent kinase 2 protein (1-298AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1 USP37, p53/TP53, NPM1 CDK7, RB1 BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1 B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and mod µLates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cell µLar proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. Phosphorylates CABLES1. Cyclin E/CDK2 prevents oxidative stress-mediated Ras-induced senescence by phosphorylating MYC. Involved in G1-S phase DNA damage checkpoint that prevents cells with damaged DNA from initiating mitosis; reg µLates homologous recombination-dependent repair by phosphorylating BRCA2, this phosphorylation is low in S phase when recombination is active, but increases as cells progress towards mitosis. In response to DNA damage, double-strand break repair by homologous recombination a reduction of CDK2-mediated BRCA2 phosphorylation. Phosphorylation of RB1 disturbs its interaction with E2F1. NPM1 phosphorylation by cyclin E/CDK2 promotes its dissociates from unduplicated centrosomes, thus initiating centrosome duplication. Cyclin E/CDK2-mediated phosphorylation of NPAT at G1-S transition and until prophase stim µLates the NPAT-mediated activation of histone gene transcription during S phase. Required for vitamin D-mediated growth inhibition by being itself inactivated. Involved in the nitric oxide- (NO) mediated signaling in a nitrosylation/activation-dependent manner. USP37 is activated by phosphorylation and thus triggers G1-S transition. CTNNB1 phosphorylation reg µLates ins µLin internalization. Phosphorylates FOXP3 and negatively reg µLates its transcriptional activity and protein stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Cdc2 related protein kinase antibody; cdc2-related protein kinase antibody; CDC28 antibody; CDC2A antibody; Cdk 2 antibody; CDK1 antibody; CDK2 antibody; CDK2_HUMAN antibody; CDKN2 antibody; Cell devision kinase 2 antibody; Cell division protein kinase 2 antibody; Cyclin dependent kinase 2 antibody; cyclin dependent kinase 2-alpha antibody; Cyclin-dependent kinase 2 antibody; kinase Cdc2 antibody; MPF antibody; p33 protein kinase antibody; p33(CDK2) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24941
Immunogen : Recombinant Human Cyclin-dependent kinase 2 protein (1-298AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1 USP37, p53/TP53, NPM1 CDK7, RB1 BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1 B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and mod µLates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cell µLar proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. Phosphorylates CABLES1. Cyclin E/CDK2 prevents oxidative stress-mediated Ras-induced senescence by phosphorylating MYC. Involved in G1-S phase DNA damage checkpoint that prevents cells with damaged DNA from initiating mitosis; reg µLates homologous recombination-dependent repair by phosphorylating BRCA2, this phosphorylation is low in S phase when recombination is active, but increases as cells progress towards mitosis. In response to DNA damage, double-strand break repair by homologous recombination a reduction of CDK2-mediated BRCA2 phosphorylation. Phosphorylation of RB1 disturbs its interaction with E2F1. NPM1 phosphorylation by cyclin E/CDK2 promotes its dissociates from unduplicated centrosomes, thus initiating centrosome duplication. Cyclin E/CDK2-mediated phosphorylation of NPAT at G1-S transition and until prophase stim µLates the NPAT-mediated activation of histone gene transcription during S phase. Required for vitamin D-mediated growth inhibition by being itself inactivated. Involved in the nitric oxide- (NO) mediated signaling in a nitrosylation/activation-dependent manner. USP37 is activated by phosphorylation and thus triggers G1-S transition. CTNNB1 phosphorylation reg µLates ins µLin internalization. Phosphorylates FOXP3 and negatively reg µLates its transcriptional activity and protein stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Cdc2 related protein kinase antibody; cdc2-related protein kinase antibody; CDC28 antibody; CDC2A antibody; Cdk 2 antibody; CDK1 antibody; CDK2 antibody; CDK2_HUMAN antibody; CDKN2 antibody; Cell devision kinase 2 antibody; Cell division protein kinase 2 antibody; Cyclin dependent kinase 2 antibody; cyclin dependent kinase 2-alpha antibody; Cyclin-dependent kinase 2 antibody; kinase Cdc2 antibody; MPF antibody; p33 protein kinase antibody; p33(CDK2) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24941
Immunogen : Recombinant Human Cyclin-dependent kinase 2 protein (1-298AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1 USP37, p53/TP53, NPM1 CDK7, RB1 BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1 B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and mod µLates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cell µLar proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. Phosphorylates CABLES1. Cyclin E/CDK2 prevents oxidative stress-mediated Ras-induced senescence by phosphorylating MYC. Involved in G1-S phase DNA damage checkpoint that prevents cells with damaged DNA from initiating mitosis; reg µLates homologous recombination-dependent repair by phosphorylating BRCA2, this phosphorylation is low in S phase when recombination is active, but increases as cells progress towards mitosis. In response to DNA damage, double-strand break repair by homologous recombination a reduction of CDK2-mediated BRCA2 phosphorylation. Phosphorylation of RB1 disturbs its interaction with E2F1. NPM1 phosphorylation by cyclin E/CDK2 promotes its dissociates from unduplicated centrosomes, thus initiating centrosome duplication. Cyclin E/CDK2-mediated phosphorylation of NPAT at G1-S transition and until prophase stim µLates the NPAT-mediated activation of histone gene transcription during S phase. Required for vitamin D-mediated growth inhibition by being itself inactivated. Involved in the nitric oxide- (NO) mediated signaling in a nitrosylation/activation-dependent manner. USP37 is activated by phosphorylation and thus triggers G1-S transition. CTNNB1 phosphorylation reg µLates ins µLin internalization. Phosphorylates FOXP3 and negatively reg µLates its transcriptional activity and protein stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK2
GeneID : 1017
Uniprot : P24941
Specificity : CDK2 Antibody detects endogenous levels of total CDK2.
Immunogen : A syntheVolumed peptide derived from human CDK2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835507
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3130-BP
Des# Blocking Peptide : CDK2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Clone Number :
Aliases : Cdc2 related protein kinase antibody; cdc2-related protein kinase antibody; CDC28 antibody; CDC2A antibody; Cdk 2 antibody; CDK1 antibody; CDK2 antibody; CDK2_HUMAN antibody; CDKN2 antibody; Cell devision kinase 2 antibody; Cell division protein kinase 2 antibody; Cyclin dependent kinase 2 antibody; cyclin dependent kinase 2-alpha antibody; Cyclin-dependent kinase 2 antibody; kinase Cdc2 antibody; MPF antibody; p33 protein kinase antibody; p33(CDK2) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24941
Immunogen : Peptide sequence around aa.158~162 (T-Y-T-H-E) derived from Human CDK2.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 1000
Background : Involved in the control of the cell cycle. Interacts with cyclins A, B1 B3, D, or E. Activity of CDK2 is maximal during S phase and G2.

Ukomadu C, et al.(2003) J Biol Chem; 278(7) : 4840-6
Morris MC, et al.(2002)J Biol Chem; 277(26) : 23847-53
Brown NR, et al.(1999)J Biol Chem; 274(13) : 8746-56
Liu Y, et al.(2004) J Biol Chem; 279(6) : 4507-14
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2
Research Areas : Epigenetics and Nuclear Signaling;Cancer;Cell biology

Volume : 50 µL
Clone Number :
Aliases : bA346C16.3 antibody; CDC2 related protein kinase 6 antibody; CDC2-related protein kinase 6 antibody; CDC2L6 antibody; CDK11 antibody; Cdk19 antibody; CDK19_HUMAN antibody; CDK8 like cyclin dependent kinase antibody; Cell division cycle 2 like 6 (CDK8 like) antibody; Cell division cycle 2 like protein kinase 6 antibody; Cell division cycle 2-like protein kinase 6 antibody; Cell division protein kinase 19 antibody; Cyclin dependent kinase (CDC2 like) 11 antibody; Cyclin dependent kinase 11 antibody; Cyclin dependent kinase 19 variant 2 antibody; Cyclin-dependent kinase 11 antibody; Cyclin-dependent kinase 19 antibody; Death preventing kinase antibody; Death-preventing kinase antibody; KIAA1028 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BWU1
Immunogen : Human CDC2L6
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK19
Research Areas : Epigenetics and Nuclear Signaling;Cell biology

Volume : 50 µL
Clone Number :
Aliases : Cdk18 antibody; CDK18_HUMAN antibody; Cell division protein kinase 18 antibody; Cyclin-dependent kinase 18 antibody; PCTAIRE 3 antibody; PCTAIRE antibody; PCTAIRE motif protein kinase 3 antibody; PCTAIRE protein kinase 3 antibody; PCTAIRE-motif protein kinase 3 antibody; PCTK 3 antibody; Serine/threonine-protein kinase PCTAIRE-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q07002
Immunogen : Human PCTK3
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK18
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 6430598J10Rik antibody; CDK17 antibody; CDK17_HUMAN antibody; Cell division protein kinase 17 antibody; Cyclin-dependent kinase 17 antibody; EC 2.7.1.37 antibody; MGC25109 antibody; PCTAIRE-motif protein kinase 2 antibody; PCTK2 antibody; Protein kinase cdc2-related PCTAIRE-2 antibody; Serine/threonine-protein kinase PCTAIRE-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00537
Immunogen : Recombinant Human Cyclin-dependent kinase 17 protein (337-523AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK17
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 6430598J10Rik antibody; CDK17 antibody; CDK17_HUMAN antibody; Cell division protein kinase 17 antibody; Cyclin-dependent kinase 17 antibody; EC 2.7.1.37 antibody; MGC25109 antibody; PCTAIRE-motif protein kinase 2 antibody; PCTK2 antibody; Protein kinase cdc2-related PCTAIRE-2 antibody; Serine/threonine-protein kinase PCTAIRE-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00537
Immunogen : Recombinant Human Cyclin-dependent kinase 17 protein (337-523AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK17
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 6430598J10Rik antibody; CDK17 antibody; CDK17_HUMAN antibody; Cell division protein kinase 17 antibody; Cyclin-dependent kinase 17 antibody; EC 2.7.1.37 antibody; MGC25109 antibody; PCTAIRE-motif protein kinase 2 antibody; PCTK2 antibody; Protein kinase cdc2-related PCTAIRE-2 antibody; Serine/threonine-protein kinase PCTAIRE-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00537
Immunogen : Recombinant Human Cyclin-dependent kinase 17 protein (337-523AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK17
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 6430598J10Rik antibody; CDK17 antibody; CDK17_HUMAN antibody; Cell division protein kinase 17 antibody; Cyclin-dependent kinase 17 antibody; EC 2.7.1.37 antibody; MGC25109 antibody; PCTAIRE-motif protein kinase 2 antibody; PCTK2 antibody; Protein kinase cdc2-related PCTAIRE-2 antibody; Serine/threonine-protein kinase PCTAIRE-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00537
Immunogen : SyntheVolumed peptide derived from the Internal region of Human PCTAIRE-2.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK17
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience;Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Cdk16 antibody; CDK16_HUMAN antibody; Cell division protein kinase 16 antibody; Cyclin-dependent kinase 16 antibody; PCTAIRE antibody; PCTAIRE protein kinase 1 antibody; PCTAIRE-motif protein kinase 1 antibody; PCTAIRE1 antibody; PCTGAIRE antibody; PCTK1 antibody; Serine/threonine-protein kinase PCTAIRE-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00536
Immunogen : Recombinant Human Cyclin-dependent kinase 16 protein (277-496AA)
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB; Recommended dilution : WB : 1 : 200-1 : 1000
Background : Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Reg µLates GH1 release by brain neurons. Phosphorylates NSF, and thereby reg µLates NSF oligomerization. Required for normal spermatogenesis. Reg µLates neuron differentiation and dendrite development (By similarity). Plays a role in the reg µLation of ins µLin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at \\\'Ser-336\\\' (in vitro).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK16
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CDK15 antibody; ALS2CR7 antibody; PFTK2Cyclin-dependent kinase 15 antibody; EC 2.7.11.22 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein antibody; Cell division protein kinase 15 antibody; Serine/threonine-protein kinase ALS2CR7 antibody; Serine/threonine-protein kinase PFTAIRE-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96Q40
Immunogen : SyntheVolumed peptide derived from the Internal region of Human ALS2CR7.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : WB, IHC, IF, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, IF : 1 : 200-1 : 1000, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK15
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CDC2 related protein kinase 5 antibody; CDC2-related protein kinase 5 antibody; CDC2L antibody; CDK13 antibody; CDK13_HUMAN antibody; cell division controller cholinesterase related antibody; cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody; cell division cycle 2 like 5 antibody; Cell division cycle 2 like protein kinase 5 antibody; Cell division cycle 2-like protein kinase 5 antibody; Cell division protein kinase 13 antibody; CHED antibody; Cholinesterase related cell division controller antibody; Cholinesterase-related cell division controller antibody; cyclin dependent kinase 13 antibody; Cyclin-dependent kinase 13 antibody; hCDK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14004
Immunogen : Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1 thereby acting as a key reg µLator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK13
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDC2 related protein kinase 5 antibody; CDC2-related protein kinase 5 antibody; CDC2L antibody; CDK13 antibody; CDK13_HUMAN antibody; cell division controller cholinesterase related antibody; cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody; cell division cycle 2 like 5 antibody; Cell division cycle 2 like protein kinase 5 antibody; Cell division cycle 2-like protein kinase 5 antibody; Cell division protein kinase 13 antibody; CHED antibody; Cholinesterase related cell division controller antibody; Cholinesterase-related cell division controller antibody; cyclin dependent kinase 13 antibody; Cyclin-dependent kinase 13 antibody; hCDK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14004
Immunogen : Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1 thereby acting as a key reg µLator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK13
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDC2 related protein kinase 5 antibody; CDC2-related protein kinase 5 antibody; CDC2L antibody; CDK13 antibody; CDK13_HUMAN antibody; cell division controller cholinesterase related antibody; cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody; cell division cycle 2 like 5 antibody; Cell division cycle 2 like protein kinase 5 antibody; Cell division cycle 2-like protein kinase 5 antibody; Cell division protein kinase 13 antibody; CHED antibody; Cholinesterase related cell division controller antibody; Cholinesterase-related cell division controller antibody; cyclin dependent kinase 13 antibody; Cyclin-dependent kinase 13 antibody; hCDK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14004
Immunogen : Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1 thereby acting as a key reg µLator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK13
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDC2 related protein kinase 5 antibody; CDC2-related protein kinase 5 antibody; CDC2L antibody; CDK13 antibody; CDK13_HUMAN antibody; cell division controller cholinesterase related antibody; cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody; cell division cycle 2 like 5 antibody; Cell division cycle 2 like protein kinase 5 antibody; Cell division cycle 2-like protein kinase 5 antibody; Cell division protein kinase 13 antibody; CHED antibody; Cholinesterase related cell division controller antibody; Cholinesterase-related cell division controller antibody; cyclin dependent kinase 13 antibody; Cyclin-dependent kinase 13 antibody; hCDK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14004
Immunogen : Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background : Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1 thereby acting as a key reg µLator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK13
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : arginine/serine-rich antibody; Cdc2 related kinase arginine/serine rich antibody; CDC2 related protein kinase 7 antibody; Cdc2-related kinase antibody; CDC2-related protein kinase 7 antibody; Cdk12 antibody; CDK12_HUMAN antibody; Cell division cycle 2 related protein kinase 7 antibody; Cell division cycle 2-related protein kinase 7 antibody; Cell division protein kinase 12 antibody; CRK7 antibody; CRKR antibody; CrkRS antibody; Cyclin-dependent kinase 12 antibody; EC 2.7.11.22 antibody; hCDK12 antibody; kiaa0904 antibody; Pksc antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYV4
Immunogen : Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key reg µLator of transcription elongation. Reg µLates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates \'Ser-5\' in CTD repeats that are already phosphorylated at \'Ser-7\', but can also phosphorylate \'Ser-2\'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in reg µLation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK12
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : arginine/serine-rich antibody; Cdc2 related kinase arginine/serine rich antibody; CDC2 related protein kinase 7 antibody; Cdc2-related kinase antibody; CDC2-related protein kinase 7 antibody; Cdk12 antibody; CDK12_HUMAN antibody; Cell division cycle 2 related protein kinase 7 antibody; Cell division cycle 2-related protein kinase 7 antibody; Cell division protein kinase 12 antibody; CRK7 antibody; CRKR antibody; CrkRS antibody; Cyclin-dependent kinase 12 antibody; EC 2.7.11.22 antibody; hCDK12 antibody; kiaa0904 antibody; Pksc antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYV4
Immunogen : Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key reg µLator of transcription elongation. Reg µLates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates \'Ser-5\' in CTD repeats that are already phosphorylated at \'Ser-7\', but can also phosphorylate \'Ser-2\'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in reg µLation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK12
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : arginine/serine-rich antibody; Cdc2 related kinase arginine/serine rich antibody; CDC2 related protein kinase 7 antibody; Cdc2-related kinase antibody; CDC2-related protein kinase 7 antibody; Cdk12 antibody; CDK12_HUMAN antibody; Cell division cycle 2 related protein kinase 7 antibody; Cell division cycle 2-related protein kinase 7 antibody; Cell division protein kinase 12 antibody; CRK7 antibody; CRKR antibody; CrkRS antibody; Cyclin-dependent kinase 12 antibody; EC 2.7.11.22 antibody; hCDK12 antibody; kiaa0904 antibody; Pksc antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYV4
Immunogen : Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key reg µLator of transcription elongation. Reg µLates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates \'Ser-5\' in CTD repeats that are already phosphorylated at \'Ser-7\', but can also phosphorylate \'Ser-2\'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in reg µLation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK12
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : arginine/serine-rich antibody; Cdc2 related kinase arginine/serine rich antibody; CDC2 related protein kinase 7 antibody; Cdc2-related kinase antibody; CDC2-related protein kinase 7 antibody; Cdk12 antibody; CDK12_HUMAN antibody; Cell division cycle 2 related protein kinase 7 antibody; Cell division cycle 2-related protein kinase 7 antibody; Cell division protein kinase 12 antibody; CRK7 antibody; CRKR antibody; CrkRS antibody; Cyclin-dependent kinase 12 antibody; EC 2.7.11.22 antibody; hCDK12 antibody; kiaa0904 antibody; Pksc antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYV4
Immunogen : Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB; Recommended dilution : WB : 1 : 500-1 : 5000
Background : Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key reg µLator of transcription elongation. Reg µLates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in reg µLation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK12
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CDK11B antibody; CDC2L1 antibody; CDK11 antibody; PITSLREA antibody; PK58 antibody; Cyclin-dependent kinase 11B antibody; EC 2.7.11.22 antibody; Cell division cycle 2-like protein kinase 1 antibody; CLK-1 antibody; Cell division protein kinase 11B antibody; Galactosyltransferase-associated protein kinase p58/GTA antibody; PITSLRE serine/threonine-protein kinase CDC2L1 antibody; p58 CLK-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P21127
Immunogen : SyntheVolumed peptide derived from the N-terminal region of Human PITSLRE.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11B
Research Areas : Epigenetics and Nuclear Signaling;Cancer;Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDK11A; CDC2L2; CDC2L3; PITSLREB; Cyclin-dependent kinase 11A; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase C
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ88/P21127
Immunogen : SyntheVolumed peptide derived from the Internal region of Human Cdk11A/B.
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11A/CDK11B
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CD11A_HUMAN antibody; CDC2L2 antibody; CDC2L3 antibody; CDK11 antibody; CDK11 p110 antibody; CDK11 p46 antibody; CDK11 p58 antibody; CDK11A antibody; Cell division cycle 2 like 2 (PITSLRE proteins) antibody; Cell division cycle 2-like protein kinase 2 antibody; Cell division protein kinase 11A antibody; Cyclin-dependent kinase 11A antibody; Galactosyltransferase-associated protein kinase p58/GTA antibody; p58GTA antibody; PITSLRE antibody; PITSLRE B antibody; PITSLRE protein kinase beta antibody; PITSLRE serine/threonine-protein kinase CDC2L2 antibody; PITSLREB antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ88
Immunogen : Recombinant Human Cyclin-dependent kinase 11A protein (5-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CD11A_HUMAN antibody; CDC2L2 antibody; CDC2L3 antibody; CDK11 antibody; CDK11 p110 antibody; CDK11 p46 antibody; CDK11 p58 antibody; CDK11A antibody; Cell division cycle 2 like 2 (PITSLRE proteins) antibody; Cell division cycle 2-like protein kinase 2 antibody; Cell division protein kinase 11A antibody; Cyclin-dependent kinase 11A antibody; Galactosyltransferase-associated protein kinase p58/GTA antibody; p58GTA antibody; PITSLRE antibody; PITSLRE B antibody; PITSLRE protein kinase beta antibody; PITSLRE serine/threonine-protein kinase CDC2L2 antibody; PITSLREB antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ88
Immunogen : Recombinant Human Cyclin-dependent kinase 11A protein (5-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CD11A_HUMAN antibody; CDC2L2 antibody; CDC2L3 antibody; CDK11 antibody; CDK11 p110 antibody; CDK11 p46 antibody; CDK11 p58 antibody; CDK11A antibody; Cell division cycle 2 like 2 (PITSLRE proteins) antibody; Cell division cycle 2-like protein kinase 2 antibody; Cell division protein kinase 11A antibody; Cyclin-dependent kinase 11A antibody; Galactosyltransferase-associated protein kinase p58/GTA antibody; p58GTA antibody; PITSLRE antibody; PITSLRE B antibody; PITSLRE protein kinase beta antibody; PITSLRE serine/threonine-protein kinase CDC2L2 antibody; PITSLREB antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ88
Immunogen : Recombinant Human Cyclin-dependent kinase 11A protein (5-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CD11A_HUMAN antibody; CDC2L2 antibody; CDC2L3 antibody; CDK11 antibody; CDK11 p110 antibody; CDK11 p46 antibody; CDK11 p58 antibody; CDK11A antibody; Cell division cycle 2 like 2 (PITSLRE proteins) antibody; Cell division cycle 2-like protein kinase 2 antibody; Cell division protein kinase 11A antibody; Cyclin-dependent kinase 11A antibody; Galactosyltransferase-associated protein kinase p58/GTA antibody; p58GTA antibody; PITSLRE antibody; PITSLRE B antibody; PITSLRE protein kinase beta antibody; PITSLRE serine/threonine-protein kinase CDC2L2 antibody; PITSLREB antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ88
Immunogen : Recombinant Human Cyclin-dependent kinase 11A protein (5-216AA)
Raised in : Rabbit
Species Reactivity : Human, Rat
Tested Applications : ELISA, WB, IHC, IF; Recommended dilution : WB : 1 : 500-1 : 5000, IHC : 1 : 500-1 : 1000, IF : 1 : 50-1 : 200
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK11A,CDK11B
GeneID : 728642,984
Uniprot : Q9UQ88/P21127
Specificity : CDK11 Antibody detects endogenous levels of total CDK11.
Immunogen : A syntheVolumed peptide derived from human CDK11 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2834347
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF0608-BP
Des# Blocking Peptide : CDK11 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK10
GeneID : 8558
Uniprot : Q15131
Specificity : CDK10 Antibody detects endogenous levels of total CDK10.
Immunogen : A syntheVolumed peptide derived from human CDK10, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835653
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3285-BP
Des# Blocking Peptide : CDK10 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase; CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 pr
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493/P24941/Q00526
Immunogen : SyntheVolumed peptide derived from Human Cdk1/2/3 around the non-phosphorylation site of T14.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 5000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1/CDK2/CDK3
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience;Cell biology;Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDK1
GeneID : 983
Uniprot : P06493
Specificity : CDK1/CDC2 Antibody detects endogenous levels of total CDK1/CDC2.
Immunogen : A syntheVolumed peptide derived from human CDK1/CDC2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2834114
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF0778-BP
Des# Blocking Peptide : CDK1/CDC2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : CDK1 also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis.The antibody is specific to the 2 isoforms of CDC2.
Immunogen : cell division cycle 2, G1 to S and G2 to M
Aliases : CDC2, CDC28A, CDK1 Cell division protein kinase 1 Cyclin dependent kinase 1 DKFZp686L20222, p34 protein kinase
Observed MW : 34 kDa
Uniprot ID : P06493
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IP
Recommended dilution : WB : 1 : 200-1 : 1000; IHC : 1 : 100-1 : 400; IF : 1 : 20-1 : 200
Gene ID :
Research Area : Neuroscience, Metabolism, Immunology, Cell Division and Proliferation

Volume : 100 µL
Clone Number :
Aliases : cyclin-dependent kinase 1 p34 protein kinase cell cycle controller CDC2 cell division protein kinase 1 cell division control protein 2 homolog cell division cycle 2, G1 to S and G2 to M
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P06493
Immunogen : Recombinant fragment, corresponding to amino acids 8-298aa of human CDC2.
Raised in : Mouse
Species Reactivity : Human,Dog,Rat,Mouse
Tested Applications : ELISA,WB,ICC;Recommended dilution : WB : 1 : 500-1 : 5000,ICC : 1 : 50-1 : 200
Background :
Clonality : Monoclonal
Isotype : IgG2b
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Cell biology;Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Recombinant Human Cyclin-dependent kinase 1 protein (9-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays a key role in the control of the eukaryotic cell cycle by mod µLating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and reg µLates G1 progress and G1-S transition via association with m µLtiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1 Bcl-xL/BCL2L1 BRCA2, CALD1 CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1 CDK7, CEBPB, CHAMP1 DMD/dystrophin, EEF1 proteins/EF-1 EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1 UBE2A/hHR6A, HIST1H1 proteins/histone H1 HMGA1 HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1 MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1 MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1 NCL, NUCKS1 NPM1/numatrin, ORC1 PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1 µL40/R2, RAB4A, RAP1GAP, RCC1 RPS6KB1/S6K1 KHDRBS1/SAM68, ESPL1 SKI, BIRC5/survivin, STIP1 TEX14, beta-tub µLins, MAPT/TAU, NEDD1 VIM/vimentin, TK1 FOXO1 RUNX1/AML1 SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair. Reactivated after successf µL DNA repair thro µgh WIP1-dependent signaling leading to CDC25A/B/C-mediated dephosphorylation and restoring cell cycle progression. In proliferating cells, CDK1-mediated FOXO1 phosphorylation at the G2-M phase represses FOXO1 interaction with 14-3-3 proteins and thereby promotes FOXO1 nuclear accum µLation and transcription factor activity, leading to cell death of postmitotic neurons. The phosphorylation of beta-tub µLins reg µLates microtub µLe dynamics during mitosis. NEDD1 phosphorylation promotes PLK1-mediated NEDD1 phosphorylation and subsequent targeting of the gamma-tub µLin ring complex (gTuRC) to the centrosome, an important step for spindle formation. In addition, CC2D1A phosphorylation reg µLates CC2D1A spindle pole localization and association with SCC1/RAD21 and centriole cohesion during mitosis. The phosphorylation of Bcl-xL/BCL2L1 after prolongated G2 arrest upon DNA damage triggers apoptosis. In contrast, CASP8 phosphorylation during mitosis prevents its activation by proteolysis and subsequent apoptosis. This phosphorylation occurs in cancer cell lines, as well as in primary breast tissues and lymphocytes. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. CALD1 phosphorylation promotes Schwann cell migration during peripheral nerve regeneration. CDK1-cyclin-B complex phosphorylates NCKAP5L and mediates its dissociation from centrosomes during mitosis (PubMed : 26549230).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Recombinant Human Cyclin-dependent kinase 1 protein (9-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a key role in the control of the eukaryotic cell cycle by mod µLating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and reg µLates G1 progress and G1-S transition via association with m µLtiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1 Bcl-xL/BCL2L1 BRCA2, CALD1 CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1 CDK7, CEBPB, CHAMP1 DMD/dystrophin, EEF1 proteins/EF-1 EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1 UBE2A/hHR6A, HIST1H1 proteins/histone H1 HMGA1 HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1 MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1 MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1 NCL, NUCKS1 NPM1/numatrin, ORC1 PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1 µL40/R2, RAB4A, RAP1GAP, RCC1 RPS6KB1/S6K1 KHDRBS1/SAM68, ESPL1 SKI, BIRC5/survivin, STIP1 TEX14, beta-tub µLins, MAPT/TAU, NEDD1 VIM/vimentin, TK1 FOXO1 RUNX1/AML1 SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair. Reactivated after successf µL DNA repair thro µgh WIP1-dependent signaling leading to CDC25A/B/C-mediated dephosphorylation and restoring cell cycle progression. In proliferating cells, CDK1-mediated FOXO1 phosphorylation at the G2-M phase represses FOXO1 interaction with 14-3-3 proteins and thereby promotes FOXO1 nuclear accum µLation and transcription factor activity, leading to cell death of postmitotic neurons. The phosphorylation of beta-tub µLins reg µLates microtub µLe dynamics during mitosis. NEDD1 phosphorylation promotes PLK1-mediated NEDD1 phosphorylation and subsequent targeting of the gamma-tub µLin ring complex (gTuRC) to the centrosome, an important step for spindle formation. In addition, CC2D1A phosphorylation reg µLates CC2D1A spindle pole localization and association with SCC1/RAD21 and centriole cohesion during mitosis. The phosphorylation of Bcl-xL/BCL2L1 after prolongated G2 arrest upon DNA damage triggers apoptosis. In contrast, CASP8 phosphorylation during mitosis prevents its activation by proteolysis and subsequent apoptosis. This phosphorylation occurs in cancer cell lines, as well as in primary breast tissues and lymphocytes. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. CALD1 phosphorylation promotes Schwann cell migration during peripheral nerve regeneration. CDK1-cyclin-B complex phosphorylates NCKAP5L and mediates its dissociation from centrosomes during mitosis (PubMed : 26549230).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Recombinant Human Cyclin-dependent kinase 1 protein (9-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays a key role in the control of the eukaryotic cell cycle by mod µLating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and reg µLates G1 progress and G1-S transition via association with m µLtiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1 Bcl-xL/BCL2L1 BRCA2, CALD1 CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1 CDK7, CEBPB, CHAMP1 DMD/dystrophin, EEF1 proteins/EF-1 EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1 UBE2A/hHR6A, HIST1H1 proteins/histone H1 HMGA1 HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1 MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1 MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1 NCL, NUCKS1 NPM1/numatrin, ORC1 PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1 µL40/R2, RAB4A, RAP1GAP, RCC1 RPS6KB1/S6K1 KHDRBS1/SAM68, ESPL1 SKI, BIRC5/survivin, STIP1 TEX14, beta-tub µLins, MAPT/TAU, NEDD1 VIM/vimentin, TK1 FOXO1 RUNX1/AML1 SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair. Reactivated after successf µL DNA repair thro µgh WIP1-dependent signaling leading to CDC25A/B/C-mediated dephosphorylation and restoring cell cycle progression. In proliferating cells, CDK1-mediated FOXO1 phosphorylation at the G2-M phase represses FOXO1 interaction with 14-3-3 proteins and thereby promotes FOXO1 nuclear accum µLation and transcription factor activity, leading to cell death of postmitotic neurons. The phosphorylation of beta-tub µLins reg µLates microtub µLe dynamics during mitosis. NEDD1 phosphorylation promotes PLK1-mediated NEDD1 phosphorylation and subsequent targeting of the gamma-tub µLin ring complex (gTuRC) to the centrosome, an important step for spindle formation. In addition, CC2D1A phosphorylation reg µLates CC2D1A spindle pole localization and association with SCC1/RAD21 and centriole cohesion during mitosis. The phosphorylation of Bcl-xL/BCL2L1 after prolongated G2 arrest upon DNA damage triggers apoptosis. In contrast, CASP8 phosphorylation during mitosis prevents its activation by proteolysis and subsequent apoptosis. This phosphorylation occurs in cancer cell lines, as well as in primary breast tissues and lymphocytes. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. CALD1 phosphorylation promotes Schwann cell migration during peripheral nerve regeneration. CDK1-cyclin-B complex phosphorylates NCKAP5L and mediates its dissociation from centrosomes during mitosis (PubMed : 26549230).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as reg µLatory subunits. The kinase activity of this protein is controlled by cyclin accum µLation and destruction thro µgh the cell cycle. The phosphorylation and dephosphorylation of this protein also play important reg µLatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen : cell division cycle 2, G1 to S and G2 to M
Aliases : CDC2, CDC28A, CDKN1 P34CDC2
Observed MW : 32 kDa
Uniprot ID : P06493
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 100; IF : 1 : 50 - 1 : 200
Gene ID : 983
Research Area : Neuroscience, Metabolism, Immunology, Cell Division and Proliferation

Volume : 100 µL
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Peptide sequence around aa.17~21 (V-V-Y-K-G) derived from Human CDC2.
Raised in : Rabbit
Species Reactivity : Human, Rat
Tested Applications : ELISA, IHC; IHC : 1 : 50-1 : 100
Background : Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

Hunter, T. (1995) Cell 80, 225-236.
Wells, N.J. et al. (1999) J. Cell. Sci. 112, 3361-3371.
McGowan, C.H. and Russell, P. (1993) EMBO J. 12, 75-85.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience;Cell biology;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Peptide sequence around aa.159~163 (T-Y-T-H-E) derived from Human CDC2.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IF; WB : 1 : 500-1 : 1000, IF : 1 : 100-1 : 200
Background : Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

Ukomadu C, et al.(2003) J Biol Chem; 278(7) : 4840-6
Morris MC, et al.(2002)J Biol Chem; 277(26) : 23847-53
Brown NR, et al.(1999)J Biol Chem; 274(13) : 8746-56
Liu Y, et al.(2004) J Biol Chem; 279(6) : 4507-14
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience;Cell biology;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Peptide sequence around aa. 13~17 (G-T-Y-G-V) derived from Human CDC2.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF : 1 : 100-1 : 200
Background : Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

Y Gu, et al. (1992) EMBO J. 11(11) : 3995
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience;Cell biology;Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDIPT
GeneID : 10423
Uniprot : O14735
Specificity : CDIPT Antibody detects endogenous levels of CDIPT.
Immunogen : A syntheVolumed peptide derived from human CDIPT.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF16061-BP
Des# Blocking Peptide : CDIPT Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CADH9_HUMAN antibody; Cadherin 9 type 2 antibody; Cadherin-9 antibody; Cadherin9 antibody; CDH 9 antibody; CDH9 antibody; T1 cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLB4
Immunogen : Recombinant Human Cadherin-9 protein (131-314AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH9
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CADH9_HUMAN antibody; Cadherin 9 type 2 antibody; Cadherin-9 antibody; Cadherin9 antibody; CDH 9 antibody; CDH9 antibody; T1 cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLB4
Immunogen : Recombinant Human Cadherin-9 protein (131-314AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH9
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CADH9_HUMAN antibody; Cadherin 9 type 2 antibody; Cadherin-9 antibody; Cadherin9 antibody; CDH 9 antibody; CDH9 antibody; T1 cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLB4
Immunogen : Recombinant Human Cadherin-9 protein (131-314AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH9
Research Areas : Neuroscience; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CDH9
GeneID : 1007
Uniprot : Q9 µLB4
Specificity : CDH9 Antibody detects endogenous levels of total CDH9.
Immunogen : A syntheVolumed peptide derived from human CDH9, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835888
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3534-BP
Des# Blocking Peptide : CDH9 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CADH8_HUMAN antibody; Cadherin 8; type 2 antibody; Cadherin-8 antibody; CDH 8 antibody; Cdh8 antibody; Nbla04261 antibody; Putative protein product of Nbla04261 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55286
Immunogen : Recombinant Human Cadherin-8 protein (653-782AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH8
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CADH8_HUMAN antibody; Cadherin 8; type 2 antibody; Cadherin-8 antibody; CDH 8 antibody; Cdh8 antibody; Nbla04261 antibody; Putative protein product of Nbla04261 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55286
Immunogen : Recombinant Human Cadherin-8 protein (653-782AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH8
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CADH8_HUMAN antibody; Cadherin 8; type 2 antibody; Cadherin-8 antibody; CDH 8 antibody; Cdh8 antibody; Nbla04261 antibody; Putative protein product of Nbla04261 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55286
Immunogen : Recombinant Human Cadherin-8 protein (653-782AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH8
Research Areas : Others