HSH2D rabbit pAb - 50 μL
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al. 2003 [PubMed 12960172]). [supplied by OMIM, Mar 2008],
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