Volume : 50 µg
Clone Number :
Aliases : CNOT9 antibody; RCD1 antibody; RQCD1CCR4-NOT transcription complex subunit 9 antibody; Cell differentiation protein RQCD1 homolog antibody; Rcd-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92600
Immunogen : Recombinant Human CCR4-NOT transcription complex subunit 9 protein (1-258AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the CCR4-NOT complex which is one of the major cell µLar mRNA deadenylases and is linked to various cell µLar processes including b µLk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription reg µLation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-reg µLation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CNOT9
Research Areas : Epigenetics and Nuclear Signaling