HBP1 rabbit pAb - 50 μL

Function: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. similarity: Contains 1 AXH domain. similarity: Contains 1 HMG box DNA-binding domain. subunit: Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.