DOC11 rabbit pAb - 50 μL

Domain: The DHR-2 domain is necessary for the GEF activity. function: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. miscellaneous: 'Zizim' means 'spike' in Hebrew. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the DOCK family. similarity: Contains 1 DHR-1 (CZH-1) domain. similarity: Contains 1 DHR-2 (CZH-2) domain. similarity: Contains 1 PH domain. subunit: Interacts with CDC42.