BRAF35 rabbit pAb - 50 μL

Function: Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters. sequence Caution: Translation N-terminally extended. similarity: Contains 1 HMG box DNA-binding domain. subcellular location: Localized to condensed chromosomes in mitosis in conjunction with BRCA2. subunit: Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein. tissue specificity: Ubiquitously expressed in adult tissues.