Sp1 (Acetyl Lys703) rabbit pAb - 50 μL

Function: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter. PTM: O-glycosylated; contains N-acetylglucosamine side chains. similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family. similarity: Contains 3 C2H2-type zinc fingers. subunit: Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.