Volume : 50 µg
Clone Number :
Aliases : 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 antibody; gp120 antibody; H4P antibody; IHRP antibody; Inter-alpha-inhibitor heavy chain 4 antibody; Inter-alpha-trypsin inhibitor family heavy chain-related protein antibody; Inter-alpha-trypsin inhibitor heavy chain H4 antibody; inter-alpha-trypsin inhibitor, heavy chain-like, 1 antibody; ITI heavy chain H4 antibody; ITI-HC4 antibody; ITIH4 antibody; ITIH4_HUMAN antibody; ITIHL1 antibody; OTTHUMP00000197120 antibody; OTTHUMP00000197121 antibody; OTTHUMP00000213834 antibody; OTTHUMP00000213869 antibody; PK-120 antibody; PK120 antibody; Plasma kallikrein sensitive glycoprotein 120 antibody; PRO1851 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14624
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 protein (689-930AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH4
Research Areas : Cardiovasc µLar; Immunology

Volume : 50 µg
Clone Number :
Aliases : 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 antibody; gp120 antibody; H4P antibody; IHRP antibody; Inter-alpha-inhibitor heavy chain 4 antibody; Inter-alpha-trypsin inhibitor family heavy chain-related protein antibody; Inter-alpha-trypsin inhibitor heavy chain H4 antibody; inter-alpha-trypsin inhibitor, heavy chain-like, 1 antibody; ITI heavy chain H4 antibody; ITI-HC4 antibody; ITIH4 antibody; ITIH4_HUMAN antibody; ITIHL1 antibody; OTTHUMP00000197120 antibody; OTTHUMP00000197121 antibody; OTTHUMP00000213834 antibody; OTTHUMP00000213869 antibody; PK-120 antibody; PK120 antibody; Plasma kallikrein sensitive glycoprotein 120 antibody; PRO1851 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14624
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 protein (689-930AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH4
Research Areas : Cardiovasc µLar; Immunology

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : ITI heavy chain H4
Aliases : DKFZp686G21125, Gp120, H4P, IHRP, ITI HC4, ITI heavy chain H4, ITIH4, ITIHL1 PK 120, PK120
Observed MW : 120 kDa
Uniprot ID : Q14624
Reactivity : Human, Mouse
Application : ELISA, IHC, WB
Recommended dilution : WB : 1 : 500-1 : 1000; IHC : 1 : 20-1 : 200
Gene ID : 3700
Research Area : Metabolism

Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Human
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 50 µg
Clone Number :
Aliases : ITIH3 antibody; Inter-alpha-trypsin inhibitor heavy chain H3 antibody; ITI heavy chain H3 antibody; ITI-HC3 antibody; Inter-alpha-inhibitor heavy chain 3 antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06033
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ITIH3 antibody; Inter-alpha-trypsin inhibitor heavy chain H3 antibody; ITI heavy chain H3 antibody; ITI-HC3 antibody; Inter-alpha-inhibitor heavy chain 3 antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06033
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ITIH3 antibody; Inter-alpha-trypsin inhibitor heavy chain H3 antibody; ITI heavy chain H3 antibody; ITI-HC3 antibody; Inter-alpha-inhibitor heavy chain 3 antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06033
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH3
Research Areas : Others

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITIH3
GeneID : 3699
Uniprot : Q06033
Specificity : ITIH3 Antibody detects endogenous levels of total ITIH3.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14157-BP
Des# Blocking Peptide : ITIH3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITIH2
GeneID : 3698
Uniprot : P19823
Specificity : ITIH2 Antibody detects endogenous levels of total ITIH2.
Immunogen : A syntheVolumed peptide derived from human ITIH2, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2846473
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13454-BP
Des# Blocking Peptide : ITIH2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µL
Clone Number :
Aliases : H1P antibody; IATIH antibody; IGHEP1 antibody; Inter alpha (glob µLin) inhibitor H1 antibody; Inter alpha (glob µLin) inhibitor H1 polypeptide antibody; Inter alpha trypsin inhibitor heavy chain 1 antibody; Inter alpha trypsin inhibitor heavy chain H1 antibody; Inter-alpha-inhibitor heavy chain 1 antibody; Inter-alpha-trypsin inhibitor complex component III antibody; Inter-alpha-trypsin inhibitor heavy chain H1 antibody; ITI heavy chain H1 antibody; ITI-HC1 antibody; ITIH antibody; ITIH1 antibody; ITIH1_HUMAN antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19827
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H1 protein (403-638AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH1
Research Areas : Cell biology

Volume : 50 µL
Clone Number :
Aliases : H1P antibody; IATIH antibody; IGHEP1 antibody; Inter alpha (glob µLin) inhibitor H1 antibody; Inter alpha (glob µLin) inhibitor H1 polypeptide antibody; Inter alpha trypsin inhibitor heavy chain 1 antibody; Inter alpha trypsin inhibitor heavy chain H1 antibody; Inter-alpha-inhibitor heavy chain 1 antibody; Inter-alpha-trypsin inhibitor complex component III antibody; Inter-alpha-trypsin inhibitor heavy chain H1 antibody; ITI heavy chain H1 antibody; ITI-HC1 antibody; ITIH antibody; ITIH1 antibody; ITIH1_HUMAN antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19827
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H1 protein (403-638AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH1
Research Areas : Cell biology

Volume : 50 µL
Clone Number :
Aliases : H1P antibody; IATIH antibody; IGHEP1 antibody; Inter alpha (glob µLin) inhibitor H1 antibody; Inter alpha (glob µLin) inhibitor H1 polypeptide antibody; Inter alpha trypsin inhibitor heavy chain 1 antibody; Inter alpha trypsin inhibitor heavy chain H1 antibody; Inter-alpha-inhibitor heavy chain 1 antibody; Inter-alpha-trypsin inhibitor complex component III antibody; Inter-alpha-trypsin inhibitor heavy chain H1 antibody; ITI heavy chain H1 antibody; ITI-HC1 antibody; ITIH antibody; ITIH1 antibody; ITIH1_HUMAN antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19827
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H1 protein (403-638AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH1
Research Areas : Cell biology

Volume : 50 µL
Clone Number :
Aliases : H1P antibody; IATIH antibody; IGHEP1 antibody; Inter alpha (glob µLin) inhibitor H1 antibody; Inter alpha (glob µLin) inhibitor H1 polypeptide antibody; Inter alpha trypsin inhibitor heavy chain 1 antibody; Inter alpha trypsin inhibitor heavy chain H1 antibody; Inter-alpha-inhibitor heavy chain 1 antibody; Inter-alpha-trypsin inhibitor complex component III antibody; Inter-alpha-trypsin inhibitor heavy chain H1 antibody; ITI heavy chain H1 antibody; ITI-HC1 antibody; ITIH antibody; ITIH1 antibody; ITIH1_HUMAN antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19827
Immunogen : Synthetic peptide of Human ITIH1
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, IHC; ELISA : 1 : 2000-1 : 10000, IHC : 1 : 50-1 : 200
Background : The protein encoded by this gene is the heavy chain of a serine protease inhibitor that may serve to carry hyaluronan in plasma. This gene is part of a cluster of similar genes on chromosome 3. M µLtiple transcript variants encoding different isoforms have been found for this gene.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH1
Research Areas : Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGBL1
GeneID : 9358
Uniprot : O95965
Specificity : ITGBL1 Antibody detects endogenous levels of ITGBL1.
Immunogen : A syntheVolumed peptide derived from human ITGBL1.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF16035-BP
Des# Blocking Peptide : ITGBL1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGB8
GeneID : 3696
Uniprot : P26012
Specificity : ITGB8 Antibody detects endogenous levels of total ITGB8.
Immunogen : A syntheVolumed peptide derived from human ITGB8, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839751
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2545-BP
Des# Blocking Peptide : ITGB8 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGB7
GeneID : 3695
Uniprot : P26010
Specificity : ITGB7 Antibody detects endogenous levels of total ITGB7.
Immunogen : A syntheVolumed peptide derived from human ITGB7, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839750
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2544-BP
Des# Blocking Peptide : ITGB7 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Integrin beta-6 antibody; ITB6_HUMAN antibody; ITGB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18564
Immunogen : Recombinant Human Integrin beta-6 protein (451-586AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV : ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB6
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Integrin beta-6 antibody; ITB6_HUMAN antibody; ITGB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18564
Immunogen : Recombinant Human Integrin beta-6 protein (451-586AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV : ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB6
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Integrin beta-6 antibody; ITB6_HUMAN antibody; ITGB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18564
Immunogen : Recombinant Human Integrin beta-6 protein (451-586AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV : ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB6
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGB6
GeneID : 3694
Uniprot : P18564
Specificity : ITGB6 Antibody detects endogenous levels of total ITGB6.
Immunogen : A syntheVolumed peptide derived from human ITGB6, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Horse,Rabbit,Dog
Application : WB,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839749
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2543-BP
Des# Blocking Peptide : ITGB6 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : FLJ26658 antibody; Integrin beta-5 antibody; Integrin subunit beta 5 antibody; integrin, beta 5 antibody; ITB5_HUMAN antibody; Itgb5 antibody; Testis secretory sperm-binding protein Li 217p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18084
Immunogen : Recombinant Human Integrin beta-5 protein (431-637AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-V/beta-5 (ITGAV : ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ26658 antibody; Integrin beta-5 antibody; Integrin subunit beta 5 antibody; integrin, beta 5 antibody; ITB5_HUMAN antibody; Itgb5 antibody; Testis secretory sperm-binding protein Li 217p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18084
Immunogen : Recombinant Human Integrin beta-5 protein (431-637AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-V/beta-5 (ITGAV : ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ26658 antibody; Integrin beta-5 antibody; Integrin subunit beta 5 antibody; integrin, beta 5 antibody; ITB5_HUMAN antibody; Itgb5 antibody; Testis secretory sperm-binding protein Li 217p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18084
Immunogen : Recombinant Human Integrin beta-5 protein (431-637AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-V/beta-5 (ITGAV : ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FLJ26658 antibody; Integrin beta-5 antibody; Integrin subunit beta 5 antibody; integrin, beta 5 antibody; ITB5_HUMAN antibody; Itgb5 antibody; Testis secretory sperm-binding protein Li 217p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18084
Immunogen : SyntheVolumed peptide derived from the C-terminal region of Human Integrin ?5.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat, Monkey
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_HUMAN antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16144
Immunogen : Recombinant Human Integrin beta-4 protein (1401-1533AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the reg µLation of keratinocyte polarity and motility. ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_HUMAN antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16144
Immunogen : Recombinant Human Integrin beta-4 protein (1401-1533AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the reg µLation of keratinocyte polarity and motility. ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_HUMAN antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16144
Immunogen : Recombinant Human Integrin beta-4 protein (1401-1533AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the reg µLation of keratinocyte polarity and motility. ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_HUMAN antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16144
Immunogen : SyntheVolumed peptide derived from Human Integrin ?4 around the non-phosphorylation site of Y1510.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB4
Research Areas : Signal transduction

Volume : 100 µL
Clone Number :
Aliases : CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_HUMAN antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16144
Immunogen : SyntheVolumed non-phosphopeptide derived from Human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T).
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 3000, IHC : 1 : 50-1 : 100
Background : Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the reg µLation of keratinocyte polarity and motility.

Suzuki S., EMBO J. 9 : 757-763(1990).
Hogervorst F., EMBO J. 9 : 765-770(1990).
Tamura R.N., J. Cell Biol. 111 : 1593-1604(1990).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB4
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : ITGB3BP antibody; CENPR antibody; NRIF3Centromere protein R antibody; CENP-R antibody; Beta-3-endonexin antibody; Integrin beta-3-binding protein antibody; Nuclear receptor-interacting factor 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13352
Immunogen : Human ITGB3BP
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB, IHC
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB3BP
Research Areas : Epigenetics and Nuclear Signaling;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : GT, CD61 GP3A, BDPLT2, GPIIIa
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P05106
Immunogen : Purified recombinant human ITGB3 protein fragments expressed in E.coli.
Raised in : Mouse
Species Reactivity : Human,Dog,Rabbit,Rat,Mouse
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background : Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB3
Research Areas : Cardiovasc µLar;Immunology;Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BDPLT16 antibody; BDPLT2 antibody; CD 61 antibody; CD61 antibody; CD61 antigen antibody; GP3A antibody; GPIIIa antibody; GT antibody; HPA 1 antibody; HPA 4 antibody; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody; Integrin beta chain beta 3 antibody; Integrin beta-3 antibody; ITB3_HUMAN antibody; ITG B3 antibody; ITGB 3 antibody; ITGB3 antibody; NAIT antibody; platelet fibrinogen receptor antibody; Platelet fibrinogen receptor beta subunit antibody; Platelet fibrinogen receptor, beta subunit antibody; Platelet glycoprotein IIIa antibody; Platelet glycoprotein IIIa precursor antibody; Platelet membrane glycoprotein IIIa antibody; PTP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05106
Immunogen : SyntheVolumed peptide derived from Human Integrin ?3 around the non-phosphorylation site of Y785.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB3
Research Areas : Cardiovasc µLar;Immunology;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : BDPLT16 antibody; BDPLT2 antibody; CD 61 antibody; CD61 antibody; CD61 antigen antibody; GP3A antibody; GPIIIa antibody; GT antibody; HPA 1 antibody; HPA 4 antibody; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody; Integrin beta chain beta 3 antibody; Integrin beta-3 antibody; ITB3_HUMAN antibody; ITG B3 antibody; ITGB 3 antibody; ITGB3 antibody; NAIT antibody; platelet fibrinogen receptor antibody; Platelet fibrinogen receptor beta subunit antibody; Platelet fibrinogen receptor, beta subunit antibody; Platelet glycoprotein IIIa antibody; Platelet glycoprotein IIIa precursor antibody; Platelet membrane glycoprotein IIIa antibody; PTP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05106
Immunogen : Peptide sequence around aa.783~787 (I-T-Y-R-G) derived from Human Integrin B3/ITGB3.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 1000
Background :
The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molec µLe receptors that share a common heterotrimeric structure with a and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct a subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can res µLt from defects in the genes for either the Itg-a2B or the Itg-Beta3 subunit

Sujoy Bhattacharya, et al. (2006) Biochem J. A µgust 1; 397(Pt 3) : 437
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB3
Research Areas : Cardiovasc µLar;Immunology;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : BDPLT16 antibody; BDPLT2 antibody; CD 61 antibody; CD61 antibody; CD61 antigen antibody; GP3A antibody; GPIIIa antibody; GT antibody; HPA 1 antibody; HPA 4 antibody; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody; Integrin beta chain beta 3 antibody; Integrin beta-3 antibody; ITB3_HUMAN antibody; ITG B3 antibody; ITGB 3 antibody; ITGB3 antibody; NAIT antibody; platelet fibrinogen receptor antibody; Platelet fibrinogen receptor beta subunit antibody; Platelet fibrinogen receptor, beta subunit antibody; Platelet glycoprotein IIIa antibody; Platelet glycoprotein IIIa precursor antibody; Platelet membrane glycoprotein IIIa antibody; PTP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05106
Immunogen : Peptide sequence around aa. 771~775 (P-L-Y-K-E) derived from Human Integrin b3.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : Integrin a-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin a-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins a-IIb/beta-3 and a-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin a-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin a-IIb/beta-3 brings about platelet/platelet interaction thro µgh binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically pl µgs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracell µLar viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Chandhoke SK, et al.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB3
Research Areas : Cardiovasc µLar;Immunology;Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGB2
GeneID : 3689
Uniprot : P05107
Specificity : ITGB2/CD18 Antibody detects endogenous levels of total ITGB2/CD18.
Immunogen : A syntheVolumed peptide derived from human ITGB2/CD18, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838855
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6896-BP
Des# Blocking Peptide : ITGB2/CD18 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : 95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody; Leukocyte cell adhesion molec µLe CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05107
Immunogen : Recombinant Human Integrin beta-2 protein (37-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed : 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed : 11812992). Triggers neutrophil transmigration during lung injury thro µgh PTK2B/PYK2-mediated activation (PubMed : 18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed : 23775590).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB2
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : 95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody; Leukocyte cell adhesion molec µLe CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05107
Immunogen : Recombinant Human Integrin beta-2 protein (37-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed : 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed : 11812992). Triggers neutrophil transmigration during lung injury thro µgh PTK2B/PYK2-mediated activation (PubMed : 18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed : 23775590).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB2
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : 95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody; Leukocyte cell adhesion molec µLe CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05107
Immunogen : Recombinant Human Integrin beta-2 protein (37-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed : 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed : 11812992). Triggers neutrophil transmigration during lung injury thro µgh PTK2B/PYK2-mediated activation (PubMed : 18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed : 23775590).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB2
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : This gene encodes an integrin beta chain, which combines with m µLtiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing res µLts in m µLtiple transcript variants.
Immunogen : ITGB2
Aliases : CD18, LAD, LCAMB, LFA-1 MAC-1 MF17, MFI7
Observed MW : 85 kDa
Uniprot ID : P05107
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200; IF : 1 : 50 - 1 : 200
Gene ID : 3689
Research Area : Immunology, Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKP3
Immunogen : Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role during maturation and/or organization of muscles cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP2
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKP3
Immunogen : Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role during maturation and/or organization of muscles cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP2
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKP3
Immunogen : Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role during maturation and/or organization of muscles cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP2
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : May play a role during maturation and/or organization of muscles cells.
Immunogen : integrin beta 1 binding protein(melusin) 2
Aliases :
Observed MW : 40-45kd
Uniprot ID : Q9UKP3
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IF
Recommended dilution : WB : 1 : 500-1 : 2000; IF : 1 : 20-1 : 200
Gene ID : 26548
Research Area : Cardiovasc µLar, Developmental biology, Signal Transduction

Volume : 50 µL
Clone Number :
Aliases : ITGB1BP1 antibody; ICAP1Integrin beta-1-binding protein 1 antibody; Integrin cytoplasmic domain-associated protein 1 antibody; ICAP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14713
Immunogen : Recombinant Human Integrin beta-1-binding protein 1 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key reg µLator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stim µLates cell µLar proliferation in a fibronectin-dependent manner. Involved in the reg µLation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1 and hence stim µLates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner. Acts as a guanine nucleotide dissociation inhibitor (GDI) by reg µLating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin. Stim µLates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool. Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin. Plays a role in bone mineralization at a late stage of osteoblast differentiation; mod µLates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis. Plays a role in blood vessel development; acts as a negative reg µLator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation thro µgh activation of the Notch signaling pathway. Promotes transcriptional activity of the MYC promoter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP1
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : ITGB1BP1 antibody; ICAP1Integrin beta-1-binding protein 1 antibody; Integrin cytoplasmic domain-associated protein 1 antibody; ICAP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14713
Immunogen : Recombinant Human Integrin beta-1-binding protein 1 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Key reg µLator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stim µLates cell µLar proliferation in a fibronectin-dependent manner. Involved in the reg µLation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1 and hence stim µLates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner. Acts as a guanine nucleotide dissociation inhibitor (GDI) by reg µLating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin. Stim µLates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool. Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin. Plays a role in bone mineralization at a late stage of osteoblast differentiation; mod µLates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis. Plays a role in blood vessel development; acts as a negative reg µLator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation thro µgh activation of the Notch signaling pathway. Promotes transcriptional activity of the MYC promoter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP1
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : ITGB1BP1 antibody; ICAP1Integrin beta-1-binding protein 1 antibody; Integrin cytoplasmic domain-associated protein 1 antibody; ICAP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14713
Immunogen : Recombinant Human Integrin beta-1-binding protein 1 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key reg µLator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stim µLates cell µLar proliferation in a fibronectin-dependent manner. Involved in the reg µLation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1 and hence stim µLates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner. Acts as a guanine nucleotide dissociation inhibitor (GDI) by reg µLating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin. Stim µLates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool. Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin. Plays a role in bone mineralization at a late stage of osteoblast differentiation; mod µLates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis. Plays a role in blood vessel development; acts as a negative reg µLator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation thro µgh activation of the Notch signaling pathway. Promotes transcriptional activity of the MYC promoter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP1
Research Areas : Signal transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Key reg µLator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1(heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stim µLates cell µLar proliferation in a fibronectin-dependent manner. Involved in the reg µLation of beta-1 integrin-containing focal adhesion(FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1 and hence stim µLates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner. Acts as a guanine nucleotide dissociation inhibitor(GDI) by reg µLating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin. Stim µLates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool. Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin. Plays a role in bone mineralization at a late stage of osteoblast differentiation; mod µLates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis. Plays a role in blood vessel development; acts as a negative reg µLator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation thro µgh activation of the Notch signaling pathway. Promotes transcriptional activity of the MYC promoter.
Immunogen : integrin beta 1 binding protein 1
Aliases : ICAP1
Observed MW : 22 kDa
Uniprot ID : O14713
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID : 9270
Research Area : Cardiovasc µLar, Developmental biology, Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : Itgb1 antibody; Integrin beta-1 antibody; Fibronectin receptor subunit beta antibody; VLA-4 subunit beta antibody; CD antigen CD29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P09055
Immunogen : Recombinant Mouse Integrin beta-1 protein (21-728AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Integrins alpha-1/beta-1 alpha-2/beta-1 alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1 alpha-3/beta-1 alpha-4/beta-1 alpha-5/beta-1 alpha-8/beta-1 alpha-10/beta-1 alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1 alpha-2/beta-1 alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, reg µLates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction thro µgh the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nod µLes. May be involved in up-reg µLation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1 serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successf µL completion of cytokinesis. ITGA4 : ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (By similarity). ITGA4 : ITGB1 and ITGA5 : ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Itgb1
Research Areas : Neuroscience; Developmental biology; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Itgb1 antibody; Integrin beta-1 antibody; Fibronectin receptor subunit beta antibody; VLA-4 subunit beta antibody; CD antigen CD29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P09055
Immunogen : Recombinant Mouse Integrin beta-1 protein (21-728AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Integrins alpha-1/beta-1 alpha-2/beta-1 alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1 alpha-3/beta-1 alpha-4/beta-1 alpha-5/beta-1 alpha-8/beta-1 alpha-10/beta-1 alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1 alpha-2/beta-1 alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, reg µLates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction thro µgh the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nod µLes. May be involved in up-reg µLation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1 serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successf µL completion of cytokinesis. ITGA4 : ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (By similarity). ITGA4 : ITGB1 and ITGA5 : ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Itgb1
Research Areas : Neuroscience; Developmental biology; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Itgb1 antibody; Integrin beta-1 antibody; Fibronectin receptor subunit beta antibody; VLA-4 subunit beta antibody; CD antigen CD29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P09055
Immunogen : Recombinant Mouse Integrin beta-1 protein (21-728AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Integrins alpha-1/beta-1 alpha-2/beta-1 alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1 alpha-3/beta-1 alpha-4/beta-1 alpha-5/beta-1 alpha-8/beta-1 alpha-10/beta-1 alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1 alpha-2/beta-1 alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, reg µLates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction thro µgh the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nod µLes. May be involved in up-reg µLation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1 serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successf µL completion of cytokinesis. ITGA4 : ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (By similarity). ITGA4 : ITGB1 and ITGA5 : ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Itgb1
Research Areas : Neuroscience; Developmental biology; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : beta1 integrin antibody; CD_antigen=CD29 antibody; CD29 antibody; Fibronectin receptor subunit beta antibody; FNRB antibody; Glycoprotein IIa antibody; GP IIa antibody; GPIIA antibody; Integrin beta-1 antibody; Integrin subunit beta 1 antibody; integrin VLA-4 beta subunit antibody; Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) antibody; ITB1_HUMAN antibody; ITGB1 antibody; MDF2 antibody; MSK12 antibody; OTTHUMP00000019420 antibody; very late activation protein antibody; Very late activation protein, beta polypeptide antibody; VLA BETA antibody; VLA-4 subunit beta antibody; VLA-BETA antibody; VLAB antibody; VLAbeta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05556
Immunogen : SyntheVolumed peptide derived from the Internal region of Human Integrin ?1.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1
Research Areas : Cancer;Metabolism;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : beta1 integrin antibody; CD_antigen=CD29 antibody; CD29 antibody; Fibronectin receptor subunit beta antibody; FNRB antibody; Glycoprotein IIa antibody; GP IIa antibody; GPIIA antibody; Integrin beta-1 antibody; Integrin subunit beta 1 antibody; integrin VLA-4 beta subunit antibody; Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) antibody; ITB1_HUMAN antibody; ITGB1 antibody; MDF2 antibody; MSK12 antibody; OTTHUMP00000019420 antibody; very late activation protein antibody; Very late activation protein, beta polypeptide antibody; VLA BETA antibody; VLA-4 subunit beta antibody; VLA-BETA antibody; VLAB antibody; VLAbeta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05556
Immunogen : SyntheVolumed non-phosphopeptide derived from Human Integrin ?1 around the phosphorylation site of threonine 789 (V-T-T(p)-V-V).
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 3000
Background : Integrins alpha-1/beta-1 alpha-2/beta-1 alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1 alpha-3/beta-1 alpha-4/beta-1 alpha-5/beta-1 alpha-8/beta-1 alpha-10/beta-1 alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1 alpha-2/beta-1 alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 res µLting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracell µLar viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. When associated with alpha-7/beta-1 integrin, reg µLates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction thro µgh the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nod µLes. May be involved in up-reg µLation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1/RACK1 serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successf µL completion of cytokinesis. Isoform 5 : Isoform 5 displaces isoform 1 in striated muscles By similarity.G Santoni, Microbiology, Nov 1994; 140 : 2971. Maria J. Calzada, J. Biol. Chem., Oct 2004; 279 : 41734 - 41743. Lawrence E. Feldman, Cancer Res., Feb 1991; 51 : 1065 - 1070. MF Gurish, J. Immunol., Sep 1992; 149 : 1964.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1
Research Areas : Cancer;Metabolism;Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 95 alpha chain antibody; 95 antibody; CD 11c antibody; CD11 antigen like family member C antibody; CD11 antigen-like family member C antibody; CD11c antibody; CD11c antigen antibody; Complement component 3 receptor 4 subunit antibody; CR4 antibody; Integrin alpha X antibody; Integrin alpha X chain antibody; Integrin alpha-X antibody; Integrin aX antibody; Integrin subunit alpha X antibody; integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody; integrin, alpha X (complement component 3 receptor 4 subunit antibody; ITAX_HUMAN antibody; ITGAX antibody; LEU M5 alpha subunit antibody; Leu M5 antibody; Leukocyte adhesion glycoprotein p150 95 alpha chain antibody; Leukocyte adhesion glycoprotein p150 antibody; Leukocyte adhesion receptor p150 95 antibody; Leukocyte adhesion receptor p150 antibody; Leukocyte surface antigen p150 95 alpha subunit antibody; Leukocyte surface antigen p150 alpha subunit antibody; Myeloid membrane antigen alpha subunit antibody; p150 95 integrin alpha chain antibody; p150 antibody; p150/95 antibody; SLEB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20702
Immunogen : Recombinant Human Integrin alpha-X protein (100-350AA)
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB, IHC, IF; Recommended dilution : WB : 1 : 1000-1 : 5000, IHC : 1 : 20-1 : 200, IF : 1 : 50-1 : 200
Background : Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAX
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06756
Immunogen : Recombinant Human Integrin alpha-V protein (775-885AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV : ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed : 23125415). ITGAV : ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGAV : ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed : 18441324). ITGAV : ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 19578119). ITGAV : ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGAV : ITGB3 and ITGAV : ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAV
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06756
Immunogen : Recombinant Human Integrin alpha-V protein (775-885AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV : ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed : 23125415). ITGAV : ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGAV : ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed : 18441324). ITGAV : ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 19578119). ITGAV : ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGAV : ITGB3 and ITGAV : ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAV
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06756
Immunogen : Recombinant Human Integrin alpha-V protein (775-885AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV : ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed : 23125415). ITGAV : ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGAV : ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed : 18441324). ITGAV : ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 19578119). ITGAV : ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGAV : ITGB3 and ITGAV : ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAV
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06756
Immunogen : SyntheVolumed peptide derived from the Internal region of Human Integrin ?V.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAV
Research Areas : Cancer?Cardiovasc µLar;Microbiology?Signal transduction?Stem cells

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P11215
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : 4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, gran µLocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cell µLar function of CD11b is on neutrophil and monocyte interactions with stim µLated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR et al., eds. (1987) Leucocyte Typing III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17 : 2093. Springer TA (1994) Cell 76 : 3014. Stewart M et al (1995) Curr Opin Cell Biol 7 : 690
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience;Tags & Cell Markers;Signal transduction?Stem cells

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P11215
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : 4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, gran µLocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cell µLar function of CD11b is on neutrophil and monocyte interactions with stim µLated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR et al., eds. (1987) Leucocyte Typing III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17 : 2093. Springer TA (1994) Cell 76 : 3014. Stewart M et al (1995) Curr Opin Cell Biol 7 : 690
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience;Tags & Cell Markers;Signal transduction?Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen CD11b (p170) antibody; Antigen CD11b p170 antibody; CD11 antigen like family member B antibody; CD11 antigen-like family member B antibody; CD11b antibody; CD11b/CD18 antibody; CD49d antibody; Cell surface glycoprotein MAC-1 subunit alpha antibody; Complement component 3 receptor 3 subunit antibody; Complement Component Receptor 3 Alpha antibody; Complement receptor type 3 antibody; Complement receptor type 3, alpha subunit antibody; CR 3 alpha chain (CR3A) antibody; CR 3 alpha chain antibody; CR-3 alpha chain antibody; CR3 antibody; CR3A antibody; F730045J24Rik antibody; Integrin Alpha M antibody; Integrin alpha M chain antibody; Integrin alpha-M antibody; Integrin beta 2 alpha subunit antibody; Integrin subunit alpha M antibody; integrin, alpha M (complement component 3 receptor 3 subunit) antibody; ITAM_HUMAN antibody; ITGAM antibody; Leukocyte adhesion receptor MO1 antibody; Ly-40 antibody; MAC 1 antibody; Mac-1a antibody; MAC1 antibody; Mac1 alpha subunit antibody; MAC1A antibody; Macrophage antigen alpha polypeptide antibody; MGC117044 antibody; Mo1 antibody; Mo1 alpha subunit antibody; MO1A antibody; Neutrophil adherence receptor alpha M subunit antibody; Neutrophil adherence receptor antibody; SLEB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11215
Immunogen : Recombinant Human Integrin alpha-M protein (46-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and gran µLocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience; Tags & Cell Markers; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen CD11b (p170) antibody; Antigen CD11b p170 antibody; CD11 antigen like family member B antibody; CD11 antigen-like family member B antibody; CD11b antibody; CD11b/CD18 antibody; CD49d antibody; Cell surface glycoprotein MAC-1 subunit alpha antibody; Complement component 3 receptor 3 subunit antibody; Complement Component Receptor 3 Alpha antibody; Complement receptor type 3 antibody; Complement receptor type 3, alpha subunit antibody; CR 3 alpha chain (CR3A) antibody; CR 3 alpha chain antibody; CR-3 alpha chain antibody; CR3 antibody; CR3A antibody; F730045J24Rik antibody; Integrin Alpha M antibody; Integrin alpha M chain antibody; Integrin alpha-M antibody; Integrin beta 2 alpha subunit antibody; Integrin subunit alpha M antibody; integrin, alpha M (complement component 3 receptor 3 subunit) antibody; ITAM_HUMAN antibody; ITGAM antibody; Leukocyte adhesion receptor MO1 antibody; Ly-40 antibody; MAC 1 antibody; Mac-1a antibody; MAC1 antibody; Mac1 alpha subunit antibody; MAC1A antibody; Macrophage antigen alpha polypeptide antibody; MGC117044 antibody; Mo1 antibody; Mo1 alpha subunit antibody; MO1A antibody; Neutrophil adherence receptor alpha M subunit antibody; Neutrophil adherence receptor antibody; SLEB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11215
Immunogen : Recombinant Human Integrin alpha-M protein (46-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and gran µLocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience; Tags & Cell Markers; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen CD11b (p170) antibody; Antigen CD11b p170 antibody; CD11 antigen like family member B antibody; CD11 antigen-like family member B antibody; CD11b antibody; CD11b/CD18 antibody; CD49d antibody; Cell surface glycoprotein MAC-1 subunit alpha antibody; Complement component 3 receptor 3 subunit antibody; Complement Component Receptor 3 Alpha antibody; Complement receptor type 3 antibody; Complement receptor type 3, alpha subunit antibody; CR 3 alpha chain (CR3A) antibody; CR 3 alpha chain antibody; CR-3 alpha chain antibody; CR3 antibody; CR3A antibody; F730045J24Rik antibody; Integrin Alpha M antibody; Integrin alpha M chain antibody; Integrin alpha-M antibody; Integrin beta 2 alpha subunit antibody; Integrin subunit alpha M antibody; integrin, alpha M (complement component 3 receptor 3 subunit) antibody; ITAM_HUMAN antibody; ITGAM antibody; Leukocyte adhesion receptor MO1 antibody; Ly-40 antibody; MAC 1 antibody; Mac-1a antibody; MAC1 antibody; Mac1 alpha subunit antibody; MAC1A antibody; Macrophage antigen alpha polypeptide antibody; MGC117044 antibody; Mo1 antibody; Mo1 alpha subunit antibody; MO1A antibody; Neutrophil adherence receptor alpha M subunit antibody; Neutrophil adherence receptor antibody; SLEB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11215
Immunogen : Recombinant Human Integrin alpha-M protein (46-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and gran µLocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience; Tags & Cell Markers; Signal transduction; Stem cells

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGAM
GeneID : 3684
Uniprot : P11215
Specificity : ITGAM Antibody detects endogenous levels of total ITGAM.
Immunogen : A syntheVolumed peptide derived from human ITGAM, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human
Prediction : Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839747
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2541-BP
Des# Blocking Peptide : ITGAM Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P20701
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : 4A122 reacts with CD11a, a 180 kDa molec µLe. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and gran µLocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate.1. Schlossman. S et al. (1995) Leucocyte Typing V : White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16 : 479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7 : 99.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology;Signal transduction?Stem cells

Volume : 100 µL
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P20701
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,IF,FC;Recommended dilution : IF : 1 : 100-1 : 200
Background : 4A122 reacts with CD11a, a 180 kDa molec µLe. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and gran µLocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate.1. Schlossman. S et al. (1995) Leucocyte Typing V : White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16 : 479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7 : 99.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology;Signal transduction?Stem cells

Volume : 50 µg
Clone Number :
Aliases : Antigen CD11A (p180); lymphocyte function associated antigen 1; alpha polypeptide antibody; CD11 antigen-like family member A antibody; CD11a antibody; CD18 antibody; CR3 antibody; Integrin alpha-L antibody; Integrin beta 2 antibody; Integrin gene promoter antibody; ITAL_HUMAN antibody; Itgal antibody; ITGAM antibody; ITGB2 antibody; LAD antibody; Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody; Leukocyte function-associated molec µLe 1 alpha chain antibody; LFA 1 alpha antibody; LFA 1 antibody; LFA-1A antibody; LFA1 antibody; LFA1A antibody; Lymphocyte function associated antigen 1 antibody; MAC1 antibody; MFI7 antibody; MO1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20701
Immunogen : Recombinant Human Integrin alpha-L protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by gran µLocytes and monocytes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Antigen CD11A (p180); lymphocyte function associated antigen 1; alpha polypeptide antibody; CD11 antigen-like family member A antibody; CD11a antibody; CD18 antibody; CR3 antibody; Integrin alpha-L antibody; Integrin beta 2 antibody; Integrin gene promoter antibody; ITAL_HUMAN antibody; Itgal antibody; ITGAM antibody; ITGB2 antibody; LAD antibody; Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody; Leukocyte function-associated molec µLe 1 alpha chain antibody; LFA 1 alpha antibody; LFA 1 antibody; LFA-1A antibody; LFA1 antibody; LFA1A antibody; Lymphocyte function associated antigen 1 antibody; MAC1 antibody; MFI7 antibody; MO1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20701
Immunogen : Recombinant Human Integrin alpha-L protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by gran µLocytes and monocytes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Antigen CD11A (p180); lymphocyte function associated antigen 1; alpha polypeptide antibody; CD11 antigen-like family member A antibody; CD11a antibody; CD18 antibody; CR3 antibody; Integrin alpha-L antibody; Integrin beta 2 antibody; Integrin gene promoter antibody; ITAL_HUMAN antibody; Itgal antibody; ITGAM antibody; ITGB2 antibody; LAD antibody; Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody; Leukocyte function-associated molec µLe 1 alpha chain antibody; LFA 1 alpha antibody; LFA 1 antibody; LFA-1A antibody; LFA1 antibody; LFA1A antibody; Lymphocyte function associated antigen 1 antibody; MAC1 antibody; MFI7 antibody; MO1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20701
Immunogen : Recombinant Human Integrin alpha-L protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by gran µLocytes and monocytes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGAL
GeneID : 3683
Uniprot : P20701
Specificity : ITGAL Antibody detects endogenous levels of total ITGAL.
Immunogen : A syntheVolumed peptide derived from human ITGAL, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838487
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6525-BP
Des# Blocking Peptide : ITGAL Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracell µLar domain, yielding dis µLfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molec µLe for IEL activation.
Immunogen : ITGAE
Aliases : CD103, HUMINAE
Observed MW : 110kDa
Uniprot ID : P38570
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200
Gene ID : 3682
Research Area : Immunology, Signal Transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGAD
GeneID : 3681
Uniprot : Q13349
Specificity : ITGAD Antibody detects endogenous levels of total ITGAD.
Immunogen : A syntheVolumed peptide derived from human ITGAD, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842191
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8995-BP
Des# Blocking Peptide : ITGAD Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGA9
GeneID : 3680
Uniprot : Q13797
Specificity : ITGA9 Antibody detects endogenous levels of total ITGA9.
Immunogen : A syntheVolumed peptide derived from human ITGA9, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Sheep,Rabbit,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842190
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8994-BP
Des# Blocking Peptide : ITGA9 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µL
Clone Number :
Aliases : Integrin alpha 8 antibody; Integrin alpha-8 heavy chain antibody; Integrin alpha-8 light chain antibody; ITA8_HUMAN antibody; ITGA 8 antibody; ITGA8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53708
Immunogen : Peptide sequence from Human Integrin alpha-8 protein (114-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by reg µLating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1 SPP1 TGFB1 TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and reg µLates neurite outgrowth of sensory and motor neurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA8
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Integrin alpha 8 antibody; Integrin alpha-8 heavy chain antibody; Integrin alpha-8 light chain antibody; ITA8_HUMAN antibody; ITGA 8 antibody; ITGA8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53708
Immunogen : Peptide sequence from Human Integrin alpha-8 protein (114-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by reg µLating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1 SPP1 TGFB1 TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and reg µLates neurite outgrowth of sensory and motor neurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA8
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Integrin alpha 8 antibody; Integrin alpha-8 heavy chain antibody; Integrin alpha-8 light chain antibody; ITA8_HUMAN antibody; ITGA 8 antibody; ITGA8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53708
Immunogen : Peptide sequence from Human Integrin alpha-8 protein (114-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by reg µLating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1 SPP1 TGFB1 TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and reg µLates neurite outgrowth of sensory and motor neurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA8
Research Areas : Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGA8
GeneID : 8516
Uniprot : P53708
Specificity : ITGA8 Antibody detects endogenous levels of total ITGA8.
Immunogen : A syntheVolumed peptide derived from human ITGA8, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Horse,Sheep,Dog
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842189
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8993-BP
Des# Blocking Peptide : ITGA8 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : alpha 7 antibody; FLJ25220 antibody; Integrin alpha 7 antibody; Integrin alpha 7 chain antibody; Integrin alpha 7 heavy chain antibody; Integrin alpha 7 light chain antibody; Integrin alpha-7 70 kDa form antibody; ITA7_HUMAN antibody; ITGA 7 antibody; Itga7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13683
Immunogen : Recombinant Human Integrin alpha-7 protein (175-283AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and ad µLt myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vasc µLar smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA7
Research Areas : Cancer; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : alpha 7 antibody; FLJ25220 antibody; Integrin alpha 7 antibody; Integrin alpha 7 chain antibody; Integrin alpha 7 heavy chain antibody; Integrin alpha 7 light chain antibody; Integrin alpha-7 70 kDa form antibody; ITA7_HUMAN antibody; ITGA 7 antibody; Itga7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13683
Immunogen : Recombinant Human Integrin alpha-7 protein (175-283AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and ad µLt myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vasc µLar smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA7
Research Areas : Cancer; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : alpha 7 antibody; FLJ25220 antibody; Integrin alpha 7 antibody; Integrin alpha 7 chain antibody; Integrin alpha 7 heavy chain antibody; Integrin alpha 7 light chain antibody; Integrin alpha-7 70 kDa form antibody; ITA7_HUMAN antibody; ITGA 7 antibody; Itga7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13683
Immunogen : Recombinant Human Integrin alpha-7 protein (175-283AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and ad µLt myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vasc µLar smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA7
Research Areas : Cancer; Cardiovasc µLar; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGA7
GeneID : 3679
Uniprot : Q13683
Specificity : ITGA7 Antibody detects endogenous levels of total ITGA7.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13950-BP
Des# Blocking Peptide : ITGA7 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Alpha6p antibody; CD49 antigen-like family member F antibody; CD49f antibody; Integrin alpha6B antibody; Integrin, alpha 6 antibody; ITA6_HUMAN antibody; ITGA6 antibody; ITGA6B antibody; Processed integrin alpha-6 antibody; VLA 6 antibody; VLA-6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P23229
Immunogen : Recombinant Human Integrin alpha-6 protein (625-866AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA6
Research Areas : Developmental biology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Alpha6p antibody; CD49 antigen-like family member F antibody; CD49f antibody; Integrin alpha6B antibody; Integrin, alpha 6 antibody; ITA6_HUMAN antibody; ITGA6 antibody; ITGA6B antibody; Processed integrin alpha-6 antibody; VLA 6 antibody; VLA-6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P23229
Immunogen : Recombinant Human Integrin alpha-6 protein (625-866AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA6
Research Areas : Developmental biology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Alpha6p antibody; CD49 antigen-like family member F antibody; CD49f antibody; Integrin alpha6B antibody; Integrin, alpha 6 antibody; ITA6_HUMAN antibody; ITGA6 antibody; ITGA6B antibody; Processed integrin alpha-6 antibody; VLA 6 antibody; VLA-6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P23229
Immunogen : Recombinant Human Integrin alpha-6 protein (625-866AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA6
Research Areas : Developmental biology; Signal transduction; Stem cells

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ITGA6
GeneID : 3655
Uniprot : P23229
Specificity : ITGA6 Antibody detects endogenous levels of total ITGA6.
Immunogen : A syntheVolumed peptide derived from human ITGA6, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841599
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF8323-BP
Des# Blocking Peptide : ITGA6 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08648
Immunogen : Recombinant Human Integrin alpha-5 protein (220-472AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGA5 : ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA5
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08648
Immunogen : Recombinant Human Integrin alpha-5 protein (220-472AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGA5 : ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA5
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08648
Immunogen : Recombinant Human Integrin alpha-5 protein (220-472AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGA5 : ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA5
Research Areas : Signal transduction; Stem cells

Volume : 100 µL
Host : Mouse
Clonality : Monoclonal
Isotype : IgG1
GeneName : ITGA5
GeneID : 3678
Uniprot : P08648
Specificity : ITGA5 antibody detects endogenous levels of total ITGA5.
Immunogen : Purified recombinant fragment of human ITGA5 expressed in E. Coli.
Storage : Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : WB,IHC,ELISA,FCM
Dilution : ELISA 1 : 10000, WB 1 : 500-1 : 2000, IHC 1 : 200-1 : 1000, FCM 1 : 200-1 : 400
Conj µgate : Unconj µgated
RRID : AB_2833744
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide :
Des# Blocking Peptide :
Blocking Peptide Price : $549 CAD