Nesprin-3 rabbit pAb - 50 μL

Function: Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system. similarity: Belongs to the nesprin family. similarity: Contains 1 KASH domain. similarity: Contains 2 spectrin repeats. subcellular location: Located at the rough reticulum endoplasmic (RER) in some cells. subunit: Interacts with actin-binding domain of PLEC1/plectin.