LRP3 rabbit pAb - 50 μL

Function: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. similarity: Belongs to the LDLR family. similarity: Contains 2 CUB domains. similarity: Contains 4 LDL-receptor class A domains. subunit: Binds GGA1 and GGA2. tissue specificity: Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.