GMDS rabbit pAb - 100 μL

GDP-mannose 4, 6-dehydratase (GMD; EC 4. 2. 1. 47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3, 5-epimerase, 4-reductase, designated FX in humans (MIM 137020). [supplied by OMIM, Aug 2009],