FoxK1 rabbit pAb - 100 μL

Function: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. PTM: Phosphorylated. similarity: Contains 1 FHA domain. similarity: Contains 1 fork-head DNA-binding domain. subunit: Interacts with SIN3B to form a complex which represses transcription. tissue specificity: Expressed both developing and adult tissues. In adults, significant expression is seen in tumors of the brain, colon and lymph node.