FMIP rabbit pAb - 100 μL
Function: May be involved in the differentiation of granulocytes and adipocytes. PTM: Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the THOC5 family. subcellular location: Shuttles between nucleus and cytoplasm. subunit: Interacts with phosphorylated CSF1R. tissue specificity: Ubiquitously expressed.
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