DHX58 rabbit pAb - 100 μL

Function: Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. similarity: Belongs to the helicase family. similarity: Contains 1 helicase ATP-binding domain. similarity: Contains 1 helicase C-terminal domain. subunit: Interacts with DDX58 and probably blocks its homomultimerization.