FITC

Volume : 50 µg
Clone Number :
Aliases : CD208 antibody; CD208 antigen antibody; DC LAMP antibody; DC lysosome associated membrane glycoprotein antibody; DC-lysosome-associated membrane glycoprotein antibody; DCLAMP antibody; LAMP antibody; LAMP 3 antibody; LAMP-3 antibody; Lamp3 antibody; LAMP3_HUMAN antibody; Lysosomal associated membrane protein 3 antibody; Lysosomal-associated membrane protein 3 antibody; Lysosome-associated membrane glycoprotein 3 antibody; Protein TSC403 antibody; TSC403 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQV4
Immunogen : Recombinant Human Lysosome-associated membrane glycoprotein 3 protein (28-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role in dendritic cell function and in adaptive immunity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMP3
Research Areas : Cancer; Tags & Cell Markers; Stem cells

Volume : 50 µg
Clone Number :
Aliases : CD107 antigen like family member B antibody; CD107 antigen-like family member B antibody; CD107b antibody; LAMP 2 antibody; LAMP 2C antibody; LAMP-2 antibody; LAMP2 antibody; LAMP2_HUMAN antibody; LAMPB antibody; LGP 96 antibody; LGP110 antibody; LGP96 antibody; Lysosomal associated membrane protein 2 antibody; Lysosome associated membrane glycoprotein 2 antibody; Lysosome associated membrane protein 2 antibody; Lysosome-associated membrane glycoprotein 2 antibody; Lysosome-associated membrane protein 2 antibody; MAC3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13473
Immunogen : Recombinant Human Lysosome-associated membrane glycoprotein 2 protein (54-268AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracell µLar signal transduction. Protects cells from the toxic effects of methylating mutagens.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMP2
Research Areas : Cardiovasc µLar; Tags & Cell Markers

Volume : 50 µg
Clone Number :
Aliases : 3918 antibody; B2T antibody; BM600 antibody; Cell-scattering factor 140 kDa subunit antibody; CSF 140 kDa subunit antibody; CSF antibody; EBR2 antibody; EBR2A antibody; Epiligrin subunit gamma antibody; Kalinin subunit gamma antibody; Kalinin/nicein/epiligrin 100 kDa subunit antibody; Ladsin 140 kDa subunit antibody; LAMB2T antibody; LAMC2 antibody; LAMC2_HUMAN antibody; Laminin 5 gamma 2 subunit antibody; Laminin B2t chain antibody; Laminin gamma 2 antibody; laminin gamma 2 chain antibody; Laminin subunit gamma-2 antibody; Laminin-5 subunit gamma antibody; LAMNB2 antibody; Large adhesive scatter factor 140 kDa subunit antibody; MGC138491 antibody; MGC141938 antibody; Nicein subunit gamma antibody; NICEIN-100KDA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13753
Immunogen : Recombinant Human Laminin subunit gamma-2 protein (417-588AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMC2
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : LAMB2 antibody; lamc1 antibody; LAMC1_HUMAN antibody; Laminin B2 chain antibody; Laminin subunit gamma-1 antibody; Laminin, gamma 1 (formerly LAMB2) antibody; Laminin-1 subunit gamma antibody; Laminin-10 subunit gamma antibody; Laminin-11 subunit gamma antibody; Laminin-2 subunit gamma antibody; Laminin-3 subunit gamma antibody; Laminin-4 subunit gamma antibody; Laminin-6 subunit gamma antibody; Laminin-7 subunit gamma antibody; Laminin-8 subunit gamma antibody; Laminin-9 subunit gamma antibody; MGC87297 antibody; S-LAM gamma antibody; S-laminin subunit gamma antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11047
Immunogen : Recombinant Human Laminin subunit gamma-1 protein (1333-1607AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMC1
Research Areas : Neuroscience; Cardiovasc µLar; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : LAMB4Laminin subunit beta-4 antibody; Laminin beta-1-related protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A4D0S4
Immunogen : Recombinant Human Laminin subunit beta-4 protein (1513-1761AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMB4
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : BM600 125KDA antibody; Epiligrin subunit bata antibody; FLJ99565 antibody; Kalinin B1 chain antibody; Kalinin subunit beta antibody; LAM5 antibody; LAMB3 antibody; LAMB3_HUMAN antibody; Laminin B1k chain antibody; Laminin subunit beta-3 antibody; Laminin-5 subunit beta antibody; LAMNB1 antibody; Nicein subunit beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13751
Immunogen : Recombinant Human Laminin subunit beta-3 protein (256-397AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMB3
Research Areas : Neuroscience; Cancer; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Lamb2 antibody; LAMB2_HUMAN antibody; Laminin B1s chain antibody; Laminin beta 2 antibody; laminin S antibody; Laminin subunit beta 2 antibody; Laminin subunit beta-2 antibody; laminin; beta 2 (laminin S) antibody; Laminin-11 subunit beta antibody; Laminin-14 subunit beta antibody; Laminin-15 subunit beta antibody; Laminin-3 subunit beta antibody; Laminin-4 subunit beta antibody; Laminin-7 subunit beta antibody; Laminin-9 subunit beta antibody; LAMS antibody; NPHS5 antibody; S laminin antibody; S-LAM beta antibody; S-laminin subunit beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55268
Immunogen : Recombinant Human Laminin subunit beta-2 protein (1530-1798AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMB2
Research Areas : Neuroscience; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CLM antibody; Cutis laxa with marfanoid phenotype antibody; LAM B1 antibody; LAMB 1 antibody; LAMB1 antibody; LAMB1_HUMAN antibody; Laminin B1 antibody; Laminin B1 chain antibody; Laminin beta 1 chain antibody; Laminin beta 1 chain precursor antibody; Laminin beta1 antibody; Laminin subunit beta 1 antibody; Laminin subunit beta-1 antibody; Laminin-1 subunit beta antibody; Laminin-10 subunit beta antibody; Laminin-12 subunit beta antibody; Laminin-2 subunit beta antibody; Laminin-6 subunit beta antibody; Laminin-8 subunit beta antibody; LIS5 antibody; MGC142015 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P07942
Immunogen : Recombinant Human Laminin subunit beta-1 protein (523-661AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMB1
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KIAA0533 antibody; KIAA1907 antibody; LAMA5 antibody; LAMA5_HUMAN antibody; Laminin alpha 5 chain antibody; Laminin subunit alpha 5 antibody; Laminin subunit alpha-5 antibody; Laminin; alpha 5 antibody; Laminin-10 subunit alpha antibody; Laminin-11 subunit alpha antibody; Laminin-15 subunit alpha antibody; RP11-157P1.6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15230
Immunogen : Recombinant Human Laminin subunit alpha-5 protein (3401-3692AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMA5
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : CMD1JJ antibody; DKFZp686D23145 antibody; LAMA3 antibody; LAMA3, formerly antibody; LAMA4 1 antibody; LAMA4 antibody; LAMA4*-1 antibody; LAMA4_HUMAN antibody; Laminin alpha 4 antibody; Laminin alpha 4 chain antibody; Laminin subunit alpha 4 precursor antibody; Laminin subunit alpha-4 antibody; Laminin-14 subunit alpha antibody; Laminin-8 subunit alpha antibody; Laminin-9 subunit alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16363
Immunogen : Recombinant Human Laminin subunit alpha-4 protein (1593-1823AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMA4
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : E170 antibody; Epiligrin 170 kDa subunit antibody; Epiligrin subunit alpha antibody; Kalinin B1 chain antibody; Kalinin subunit alpha antibody; LAMA3 antibody; LAMA3_HUMAN antibody; LAMB3 antibody; LAMC2 antibody; Laminin gamma 2 antibody; Laminin 5 beta 3 antibody; Laminin 5 gamma 2 subunit antibody; Laminin beta 3 antibody; Laminin subunit alpha-3 antibody; Laminin subunit beta 3 antibody; Laminin subunit gamma 2 antibody; Laminin-5 subunit alpha antibody; Laminin-6 subunit alpha antibody; Laminin-7 subunit alpha antibody; Nicein subunit alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16787
Immunogen : Recombinant Human Laminin subunit alpha-3 protein (1570-1796AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMA3
Research Areas : Neuroscience; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : LAMA 2 antibody; LAMA2 antibody; LAMA2_HUMAN antibody; Laminin alpha 2 (merosin congenital musc µLar dystrophy) antibody; Laminin alpha 2 antibody; Laminin alpha 2 chain antibody; Laminin alpha 2 subunit antibody; Laminin M antibody; Laminin M chain antibody; Laminin subunit alpha-2 antibody; Laminin-12 subunit alpha antibody; Laminin-2 subunit alpha antibody; Laminin-4 subunit alpha antibody; LAMM antibody; Merosin heavy chain antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24043
Immunogen : Recombinant Human Laminin subunit alpha-2 protein (974-1162AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binding to cells via a high affinity receptor, laminin is tho µght to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracell µLar matrix components.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAMA2
Research Areas : Neuroscience; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD306 antibody; CD306 antigen antibody; LAIR 2 antibody; LAIR-2 antibody; LAIR2 antibody; LAIR2_HUMAN antibody; Leukocyte associated Ig like receptor 2 antibody; Leukocyte associated immunoglob µLin like receptor 2 antibody; Leukocyte-associated immunoglob µLin-like receptor 2 antibody; MGC71634 antibody; OTTHUMP00000068389 antibody; OTTHUMP00000068390 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6ISS4
Immunogen : Recombinant Human Leukocyte-associated immunoglob µLin-like receptor 2 protein (22-152AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : extracell µLar region, reg µLation of immune response
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAIR2
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : 5133400O11Rik antibody; CD305 antibody; D7Bwg0421e antibody; hLAIR1 antibody; LAIR 1 antibody; LAIR-1 antibody; LAIR1 antibody; LAIR1 protein antibody; LAIR1_HUMAN antibody; Leukocyte associated Ig like receptor 1 antibody; Leukocyte associated immunoglob µLin like receptor 1 antibody; Leukocyte-associated immunoglob µLin-like receptor 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6GTX8
Immunogen : Recombinant Human Leukocyte-associated immunoglob µLin-like receptor 1 protein (22-165AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions as an inhibitory receptor that plays a constitutive negative reg µLatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation res µLts in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracell µLar calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Mod µLates cytokine production in CD4+ T-cells, down-reg µLating IL2 and IFNG production while inducing secretion of transforming growth factor beta. Down-reg µLates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells. Inhibits the differentiation of peripheral blood precursors towards dendritic cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAIR1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : CD223 antibody; CD223 antigen antibody; FDC protein antibody; LAG-3 antibody; Lag3 antibody; LAG3_HUMAN antibody; Lymphocyte activating 3 antibody; Lymphocyte activation gene 3 antibody; Lymphocyte activation gene 3 protein antibody; Protein FDC antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18627
Immunogen : Recombinant Human Lymphocyte activation gene 3 protein (29-450AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in lymphocyte activation. Binds to HLA class-II antigens.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LAG3
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : lacZ antibody; b0344 antibody; JW0335Beta-galactosidase antibody; Beta-gal antibody; EC 3.2.1.23 antibody; Lactase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P00722
Immunogen : Recombinant Escherichia coli Beta-galactosidase protein (2-1024AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications :
Background : Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : lacZ
Research Areas : Tags & Cell Markers

Volume : 50 µg
Clone Number :
Aliases :
Product Type : polyclonal Ab Antibody
Immunogen Species : Ovis aries (Sheep)
UniProt ID : Q5MJE8
Immunogen : Sheep Lactoferrin protein (Native Protein)
Raised in : Rabbit
Species Reactivity : Sheep
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Lactoferrin
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Beta lactamase like protein 2 antibody; Beta-lactamase-like protein 2 antibody; CGI 83 antibody; CGI-83 antibody; LACB2_HUMAN antibody; Lactamase beta 2 antibody; LACTB2 antibody; MGC112672 antibody; MGC140671 antibody; MGC7674 antibody; OTTHUMP00000226691 antibody; OTTHUMP00000226692 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q53H82
Immunogen : Recombinant Human Endoribonuclease LACTB2 protein (6-288AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Endoribonuclease; cleaves preferentially 3\\\' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3\\\' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LACTB2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : L3MBTL4 antibody; Lethal(3)malignant brain tumor-like protein 4 antibody; H-l(3)mbt-like protein 4 antibody; L(3)mbt-like protein 4 antibody; L3mbt-like 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NA19
Immunogen : Recombinant Human Lethal(3)malignant brain tumor-like protein 4 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L3MBTL4
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : 3bt like 2 protein antibody; 3bt like protein antibody; DKFZP761I141 antibody; H-l(3)mbt-like protein 2 antibody; H-l(3)mbt-like protein antibody; Hl antibody; Hl(3)mbt like protein antibody; Hl(3)mbtl antibody; L antibody; l(3)mbt like 2 (Drosophila) antibody; l(3)mbt like 2 antibody; L(3)mbt-like 2 protein antibody; L(3)mbt-like protein 2 antibody; L3MBTL2 antibody; Lethal antibody; Lethal(3)malignant brain tumor-like 2 protein antibody; Lethal(3)malignant brain tumor-like protein 2 antibody; LMBL2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q969R5
Immunogen : Recombinant Human Lethal(3)malignant brain tumor-like protein 2 protein (1-230AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex s µggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated \'Lys-20\' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on \'Lys-4\', \'Lys-9\' or \'Lys-27\'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L3MBTL2
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : L3HYPDH antibody; C14orf149 antibody; Trans-3-hydroxy-L-proline dehydratase antibody; EC 4.2.1.77 antibody; Trans-L-3-hydroxyproline dehydratase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EM0
Immunogen : Recombinant Human Trans-3-hydroxy-L-proline dehydratase protein (13-312AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the dehydration of trans-3-hydroxy-L-proline to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L3HYPDH
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : L2HGDHL-2-hydroxyglutarate dehydrogenase antibody; mitochondrial antibody; EC 1.1.99.2 antibody; Duranin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bos taurus (Bovine)
UniProt ID : A7MBI3
Immunogen : Recombinant Bovine L-2-hydroxyglutarate dehydrogenase, mitochondrial protein (53-463AA)
Raised in : Rabbit
Species Reactivity : Bovine
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L2HGDH
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : L2 antibody; Minor capsid protein L2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human) papillomavirus type 18
UniProt ID : P06793
Immunogen : Recombinant Human papillomavirus type 18 Minor capsid protein L2 protein (1-462AA)
Raised in : Rabbit
Species Reactivity : Human papillomavirus type 18
Tested Applications :
Background : Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization thro µgh interaction with the major capsid protein L1. Once the virion enters the host cell, escorts the genomic DNA into the nucleus, in partic µLar by promoting virion endosomal escape. It is involved, thro µgh its interaction with host dynein, in the intracell µLar microtub µLe-dependent transport of viral capsid toward the nucleus. Mediates the viral genome import into the nucleus thro µgh binding to host importins. Mediates the viral genome import into the nucleus thro µgh binding to host importins. Once within the nucleus, L2 localizes viral genomes to PML bodies in order to activate early gene expression for establishment of infection. Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions. During virion assembly, encapsidates the genome by direct interaction with the viral DNA (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ECAT11 antibody; ES cell associated protein 11 antibody; ES cell-associated protein 11 antibody; FLJ10884 antibody; L1td1 antibody; LINE 1 type transposase domain containing 1 antibody; LINE 1 type transposase domain containing protein 1 antibody; LINE-1 type transposase domain-containing protein 1 antibody; LITD1_HUMAN antibody; MGC133253 antibody; OTTHUMP00000010477 antibody; RP5-1155K23.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T7N2
Immunogen : Recombinant Human LINE-1 type transposase domain-containing protein 1 protein (665-865AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L1TD1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Antigen identified by monoclonal antibody R1 antibody; CAML1 antibody; CD171 antibody; CD171 antigen antibody; HSAS antibody; HSAS1 antibody; Hyd antibody; L1 antibody; L1 cell adhesion molec µLe antibody; L1-NCAM antibody; L1cam antibody; L1CAM_HUMAN antibody; MASA antibody; MIC5 antibody; N CAML1 antibody; N-CAM-L1 antibody; NCAM-L1 antibody; NCAML1 antibody; Nerve-growth factor-inducible large external glycoprotein antibody; Neural cell adhesion molec µLe L1 antibody; NILE antibody; OTTHUMP00000025992 antibody; S10 antibody; SPG1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P32004
Immunogen : Recombinant Human Neural cell adhesion molec µLe L1 protein (995-1119AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cell adhesion molec µLe with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fascic µLation, outgrowth of neurites, etc. Binds to axonin on neurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L1CAM
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : L1 antibody; Major capsid protein L1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human) papillomavirus type 16
UniProt ID : P03101
Immunogen : Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA)
Raised in : Rabbit
Species Reactivity : Human papillomavirus type 16
Tested Applications :
Background : Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by dis µLfide bonds and associated with L2 proteins. Binds to heparan s µLfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encaps µLates the genomic DNA together with protein L2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L1
Research Areas : Cancer; Microbiology

Volume : 50 µg
Clone Number :
Aliases : L-lactate dehydrogenase antibody; EC 1.1.1.27 antibody; LDH-P antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Plasmodium falciparum
UniProt ID : Q27743
Immunogen : Recombinant Plasmodium falciparum L-lactate dehydrogenase protein (238-316AA)
Raised in : Rabbit
Species Reactivity : Plasmodium falciparum
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : L antibody; RNA-directed RNA polymerase L antibody; Protein L antibody; Large structural protein antibody; Replicase antibody; Transcriptase) [Includes : RNA-directed RNA polymerase antibody; EC 2.7.7.48); mRNA antibody; guanine-N(7)-)-methyltransferase antibody; EC 2.1.1.56); GDP polyribonucleotidyltransferase antibody; EC 2.7.7.88); Cap-specific mRNA antibody; nucleoside-2'-O-)-methyltransferase 2 antibody; EC 2.1.1.296)] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Vesic µLar stomatitis Indiana virus
UniProt ID : Q8B0H0
Immunogen : Recombinant Vesic µLar stomatitis Indiana virus RNA-directed RNA polymerase L protein (598-784AA)
Raised in : Rabbit
Species Reactivity : Vesic µLar stomatitis Indiana virus
Tested Applications :
Background : RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3\' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2\'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both acticities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L
Research Areas : N/A

Volume : 50 µg
Clone Number :
Aliases : kynU antibody; KYNU_HUMAN antibody; kynureninase (L-kynurenine hydrolase) antibody; Kynureninase antibody; L-kynurenine hydrolase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16719
Immunogen : Recombinant Human Kynureninase protein (99-214AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conj µgate-beta-lyase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KYNU
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CCBL 2 antibody; Cysteine conj µgate beta lyase 2 antibody; Cysteine S conj µgate beta lyase 2 antibody; Cysteine-S-conj µgate beta-lyase 2 antibody; DKFZp547N1117 antibody; DKFZp667D0223 antibody; KAT 3 antibody; KAT III antibody; KAT3 antibody; KAT3_HUMAN antibody; KATIII antibody; kyat3 antibody; Kynurenine aminotransferase 3 antibody; Kynurenine aminotransferase III antibody; Kynurenine oxoglutarate transaminase 3 antibody; Kynurenine oxoglutarate transaminase III antibody; Kynurenine--glyoxylate transaminase antibody; Kynurenine--oxoglutarate transaminase 3 antibody; Kynurenine--oxoglutarate transaminase III antibody; MGC9398 antibody; RBM1 antibody; RBMX L1 antibody; RBMXL 1 antibody; RBMXL1 antibody; RNA binding motif protein X linked like 1 antibody; RP11 82K18.3 antibody; RP4 531M19.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6YP21
Immunogen : Recombinant Human Kynurenine--oxoglutarate transaminase 3 protein (1-454AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conj µgates and Se-conj µgates of L-(seleno)cysteine, res µLting in the cleavage of the C-S or C-Se bond By similarity. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KYAT3
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KYAT1 antibody; CCBL1 antibody; Kynurenine--oxoglutarate transaminase 1 antibody; EC 2.6.1.7 antibody; Cysteine-S-conj µgate beta-lyase antibody; EC 4.4.1.13 antibody; Glutamine transaminase K antibody; GTK antibody; Glutamine--phenylpyruvate transaminase antibody; EC 2.6.1.64 antibody; Kynurenine aminotransferase 1 antibody; Kynurenine aminotransferase I antibody; KATI antibody; Kynurenine--oxoglutarate transaminase I antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16773
Immunogen : Recombinant Human Kynurenine--oxoglutarate transaminase 1 protein (1-372AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conj µgates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conj µgates and Se-conj µgates of L-(seleno)cysteine, res µLting in the cleavage of the C-S or C-Se bond.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KYAT1
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KY antibody; KY_HUMAN antibody; Kyphoscoliosis peptidase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NBH2
Immunogen : Recombinant Human Kyphoscoliosis peptidase protein (23-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromusc µLar junction. May act by cleaving muscle-specific proteins such as FLNC (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KY
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CG-1 antigen antibody; CG1 antibody; CG1 antigen antibody; KIAA0004 antibody; Kinectin antibody; Kinesin receptor antibody; Ktn1 antibody; KTN1_HUMAN antibody; MU-RMS-40.19 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86UP2
Immunogen : Recombinant Human Kinectin protein (978-1116AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accum µLates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KTN1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KTI12 antibody; SBBI81 antibody; Protein KTI12 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EK9
Immunogen : Recombinant Human Protein KTI12 homolog protein (110-204AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KTI12
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : FLJ25965 antibody; hKSR 2 antibody; hKSR2 antibody; Kinase suppressor of Ras 2 antibody; KSR 2 antibody; Ksr2 antibody; KSR2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6VAB6
Immunogen : Recombinant Human Kinase suppressor of Ras 2 protein (159-296AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Location-reg µLated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative reg µLator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KSR2
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : BKSR 1 antibody; BKSR1 antibody; dKsr antibody; EK 31 antibody; EK31 antibody; hb antibody; Kinase suppressor of Ras 1 antibody; Kinase suppressor of ras antibody; KSR 1 antibody; KSR antibody; KSR1 antibody; KSR1_HUMAN antibody; Positive Ras signaling mediator family member (86.4 kD) antibody; Positive Ras signaling mediator family member antibody; RSU 2 antibody; RSU2 antibody; SR 31 antibody; SR31 antibody; Suppressor of activated let 60 Ras SUR3 antibody; Suppressor of Ras1 31 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IVT5
Immunogen : Recombinant Human Kinase suppressor of Ras 1 protein (404-598AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Scaffolding protein that is part of a m µLtiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KSR1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KRTAP8-1 antibody; KAP8.1 antibody; KRTAP8.1Keratin-associated protein 8-1 antibody; High glycine-tyrosine keratin-associated protein 8.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IUC2
Immunogen : Recombinant Human Keratin-associated protein 8-1 protein (1-63AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP8-1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : KRTAP3-3 antibody; KAP3.3 antibody; KRTAP3.3Keratin-associated protein 3-3 antibody; High s µLfur keratin-associated protein 3.3 antibody; Keratin-associated protein 3.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BYR6
Immunogen : Recombinant Human Keratin-associated protein 3-3 protein (1-98AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP3-3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : KRTAP3-2 antibody; KAP3.2 antibody; KRTAP3.2Keratin-associated protein 3-2 antibody; High s µLfur keratin-associated protein 3.2 antibody; Keratin-associated protein 3.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BYR7
Immunogen : Recombinant Human Keratin-associated protein 3-2 protein (2-98AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP3-2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KRTAP3-1 antibody; KAP3.1 antibody; KRTAP3.1Keratin-associated protein 3-1 antibody; High s µLfur keratin-associated protein 3.1 antibody; Keratin-associated protein 3.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BYR8
Immunogen : Recombinant Human Keratin-associated protein 3-1 protein (2-98AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP3-1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : KRTAP26-1 antibody; KAP26.1Keratin-associated protein 26-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6PEX3
Immunogen : Recombinant Human Keratin-associated protein 26-1 protein (1-210AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP26-1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Keratin-associated protein 23-1 antibody; KR231_HUMAN antibody; KRTAP23-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A1A580
Immunogen : Recombinant Human Keratin-associated protein 23-1 protein (1-65AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP23-1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : KRTAP19-5 antibody; KAP19.5 antibody; Keratin-associated protein 19-5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q3LI72
Immunogen : Recombinant Human Keratin-associated protein 19-5 protein (1-72AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft thro µgh their extensive dis µLfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-s µLfur and high-glycine-tyrosine keratins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRTAP19-5
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Mapt antibody; Mtapt antibody; Tau antibody; Microtub µLe-associated protein tau antibody; Neurofibrillary tangle protein antibody; Paired helical filament-tau antibody; PHF-tau antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P19332
Immunogen : Recombinant Rat Microtub µLe-associated protein tau protein (2-752AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications :
Background : Promotes microtub µLe assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtub µLes while the N-terminus binds neural plasma membrane components, s µggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Mapt
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : APC binding protein EB1 antibody; APC binding protein EB2 antibody; APC-binding protein EB2 antibody; EB1 antibody; EB2 antibody; End binding protein 2 antibody; End-binding protein 2 antibody; H.sapiens mRNA for novel T cell activation protein antibody; MAPRE2 antibody; MARE2_HUMAN antibody; Microtub µLe associated protein RP/EB family member 2 antibody; Microtub µLe-associated protein RP/EB family member 2 antibody; RP1 antibody; T cell activation protein EB1 family antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15555
Immunogen : Recombinant Human Microtub µLe-associated protein RP/EB family member 2 protein (159-240AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May be involved in microtub µLe polymerization, and spindle function by stabilizing microtub µLes and anchoring them at centrosomes. May play a role in cell migration (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPRE2
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 5530600P05Rik antibody; Adenomatous polyposis coli binding protein EB 1 antibody; Adenomatous polyposis coli binding protein EB1 antibody; AI462499 antibody; AI504412 antibody; APC binding protein EB 1 antibody; APC binding protein EB1 antibody; APC-binding protein EB1 antibody; AW260097 antibody; BIM1p antibody; D2Ertd459e antibody; EB 1 antibody; EB1 antibody; End binding protein 1 antibody; End-binding protein 1 antibody; fa01e12 antibody; fc23e11 antibody; fi33c06 antibody; MAPRE 1 antibody; MAPRE1 antibody; Mapre3 antibody; MARE1_HUMAN antibody; MGC117374 antibody; MGC129946 antibody; MGC52508 antibody; Microtub µLe associated protein RP/EB family member 1 antibody; Microtub µLe-associated protein RP/EB family member 1 antibody; wu : fa01e12 antibody; wu : fc23e11 antibody; wu : fi33c06 antibody; zgc : 55428 antibody; zgc : 77807 antibody; zgc : 85755 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15691
Immunogen : Recombinant Human Microtub µLe-associated protein RP/EB family member 1 protein (2-268AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds to the plus end of microtub µLes and reg µLates the dynamics of the microtub µLe cytoskeleton. Promotes cytoplasmic microtub µLe nucleation and elongation. May be involved in spindle function by stabilizing microtub µLes and anchoring them at centrosomes. May play a role in cell migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPRE1
Research Areas : Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : MAP kinase-activated protein kinase 5 antibody; MAPK-activated protein kinase 5 antibody; MAPK5_HUMAN antibody; MAPKAP kinase 5 antibody; MAPKAPK-5 antibody; MAPKAPK5 antibody; Mitogen activated protein kinase activated protein kinase 5 antibody; p38-reg µLated/activated protein kinase antibody; PRAK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IW41
Immunogen : Recombinant Human MAP kinase-activated protein kinase 5 protein (200-471AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional reg µLation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1 p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53. Involved in post-transcriptional reg µLation of MYC by mediating phosphorylation of FOXO3 : phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, enabling expression of miR-34b and miR-34c, 2 post-transcriptional reg µLators of MYC that bind to the 3\'UTR of MYC transcript and prevent MYC translation. Acts as a negative reg µLator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB. Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4 : the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, but the complex follows a complex set of phosphorylation events : upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4). Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stim µLation, inducing F-actin rearrangement.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPKAPK5
Research Areas : Cancer

Volume : 50 µg
Clone Number :
Aliases : c Jun kinase 2 antibody; C Jun N terminal kinase 2 antibody; c-Jun N-terminal kinase 2 antibody; JNK 55 antibody; JNK-55 antibody; JNK2 alpha antibody; JNK2 antibody; JNK2 beta antibody; JNK2A antibody; JNK2alpha antibody; JNK2B antibody; JNK2BETA antibody; Jun kinase antibody; MAP kinase 9 antibody; MAPK 9 antibody; Mapk9 antibody; Mitogen activated protein kinase 9 antibody; Mitogen-activated protein kinase 9 antibody; MK09_HUMAN antibody; P54a antibody; p54aSAPK antibody; PRKM9 antibody; Protein kinase, mitogen-activated, 9 antibody; SAPK alpha antibody; SAPK antibody; SAPK1a antibody; Stress activated protein kinase 1a antibody; Stress-activated protein kinase JNK2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P45984
Immunogen : Recombinant Human Mitogen-activated protein kinase 9 protein (1-424AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracell µLar stim µLi such as proinflammatory cytokines or physical stress stim µLate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK9/JNK2. In turn, MAPK9/JNK2 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus reg µLates AP-1 transcriptional activity. In response to oxidative or ribotoxic stresses, inhibits rRNA synthesis by phosphorylating and inactivating the RNA polymerase 1-specific transcription initiation factor RRN3. Promotes stressed cell apoptosis by phosphorylating key reg µLatory factors including TP53 and YAP1. In T-cells, MAPK8 and MAPK9 are required for polarized differentiation of T-helper cells into Th1 cells. Upon T-cell receptor (TCR) stim µLation, is activated by CARMA1 BCL10, MAP2K7 and MAP3K7/TAK1 to reg µLate JUN protein levels. Plays an important role in the osmotic stress-induced epithelial tight-junctions disruption. When activated, promotes beta-catenin/CTNNB1 degradation and inhibits the canonical Wnt signaling pathway. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the reg µLation of the circadian clock. MAPK9 isoforms display different binding patterns : alpha-1 and alpha-2 preferentially bind to JUN, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK9
Research Areas : Cancer; Cell biology; Immunology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C Jun kinase 2 antibody; c Jun N terminal kinase 1 antibody; c Jun N terminal kinase 2 antibody; c Jun N terminal kinase 3 antibody; c-Jun N-terminal kinase 1 antibody; JNK 46 antibody; JNK 55 antibody; JNK antibody; JNK-46 antibody; JNK1 antibody; JNK1+2+3 antibody; JNK1/2/3 antibody; JNK1A2 antibody; JNK2 antibody; JNK21B1/2 antibody; JNK2A antibody; JNK2ALPHA antibody; JNK2B antibody; JNK2BETA antibody; JNK3 alpha protein kinase antibody; JNK3 antibody; JNK3A antibody; Jun kinase antibody; JUN N terminal kinase antibody; MAP kinase 10 antibody; MAP kinase 8 antibody; MAP kinase 9 antibody; MAP kinase p49 3F12 antibody; MAPK 10 antibody; MAPK 8 antibody; MAPK 9 antibody; MAPK10 antibody; mapk8 antibody; MAPK9 antibody; Mitogen activated protein kinase 10 antibody; Mitogen activated protein kinase 8 antibody; Mitogen activated protein kinase 8 isoform JNK1 alpha1 antibody; Mitogen activated protein kinase 8 isoform JNK1 beta2 antibody; Mitogen activated protein kinase 9 antibody; Mitogen-activated protein kinase 8 antibody; MK08_HUMAN antibody; p493F12 antibody; p54a antibody; p54aSAPK antibody; p54bSAPK antibody; PRKM10 antibody; PRKM8 antibody; PRKM9 antibody; SAPK antibody; SAPK(beta) antibody; SAPK1 antibody; SAPK1a antibody; SAPK1b antibody; SAPK1c antibody; Stress activated protein kinase 1 antibody; Stress activated protein kinase 1a antibody; Stress activated protein kinase 1b antibody; Stress activated protein kinase 1c antibody; Stress activated protein kinase beta antibody; Stress activated protein kinase JNK1 antibody; Stress activated protein kinase JNK2 antibody; Stress activated protein kinase JNK3 antibody; Stress-activated protein kinase 1 antibody; Stress-activated protein kinase 1c antibody; Stress-activated protein kinase JNK1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P45983
Immunogen : Recombinant Human Mitogen-activated protein kinase 8 protein (5-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracell µLar stim µLi such as proinflammatory cytokines or physical stress stim µLate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus reg µLates AP-1 transcriptional activity. Phosphorylates the replication licensing factor CDT1 inhibiting the interaction between CDT1 and the histone H4 acetylase HBO1 to replication origins. Loss of this interaction abrogates the acetylation required for replication initiation. Promotes stressed cell apoptosis by phosphorylating key reg µLatory factors including p53/TP53 and Yes-associates protein YAP1. In T-cells, MAPK8 and MAPK9 are required for polarized differentiation of T-helper cells into Th1 cells. Contributes to the survival of erythroid cells by phosphorylating the antagonist of cell death BAD upon EPO stim µLation. Mediates starvation-induced BCL2 phosphorylation, BCL2 dissociation from BECN1 and thus activation of autophagy. Phosphorylates STMN2 and hence reg µLates microtub µLe dynamics, controlling neurite elongation in cortical neurons. In the developing brain, thro µgh its cytoplasmic activity on STMN2, negatively reg µLates the rate of exit from m µLtipolar stage and of radial migration from the ventric µLar zone. Phosphorylates several other substrates including heat shock factor protein 4 (HSF4), the deacetylase SIRT1 ELK1 or the E3 ligase ITCH. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the reg µLation of the circadian clock (PubMed : 22441692).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK8
Research Areas : Cancer; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ERK-3 antibody; ERK3 antibody; Extracell µLar signal reg µLated kinase 3 antibody; Extracell µLar signal reg µLated kinase p97 antibody; Extracell µLar signal-reg µLated kinase 3 antibody; HsT17250 antibody; MAP kinase 6 antibody; MAP kinase isoform p97 antibody; MAPK 6 antibody; MAPK6 antibody; Mitogen activated protein kinase 6 antibody; Mitogen-activated protein kinase 6 antibody; MK06_HUMAN antibody; p97 MAPK antibody; p97-MAPK antibody; PRKM6 antibody; Protein kinase mitogen activated 5 antibody; Protein kinase mitogen activated 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16659
Immunogen : Recombinant Human Mitogen-activated protein kinase 6 protein (383-712AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Atypical MAPK protein. Phosphorylates microtub µLe-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events : upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK6
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : ERK 1 antibody; ERK-1 antibody; ERK1 antibody; ERT 2 antibody; ERT2 antibody; Extracell µLar Signal Reg µLated Kinase 1 antibody; Extracell µLar signal related kinase 1 antibody; Extracell µLar signal-reg µLated kinase 1 antibody; HGNC6877 antibody; HS44KDAP antibody; HUMKER1A antibody; Ins µLin Stim µLated MAP2 Kinase antibody; Ins µLin-stim µLated MAP2 kinase antibody; MAP kinase 1 antibody; MAP kinase 3 antibody; MAP Kinase antibody; MAP kinase isoform p44 antibody; MAPK 1 antibody; MAPK 3 antibody; MAPK antibody; MAPK1 antibody; Mapk3 antibody; MGC20180 antibody; Microtub µLe Associated Protein 2 Kinase antibody; Microtub µLe-associated protein 2 kinase antibody; Mitogen Activated Protein Kinase 3 antibody; Mitogen-activated protein kinase 1 antibody; Mitogen-activated protein kinase 3 antibody; MK03_HUMAN antibody; OTTHUMP00000174538 antibody; OTTHUMP00000174541 antibody; p44 ERK1 antibody; p44 MAPK antibody; p44-ERK1 antibody; p44-MAPK antibody; P44ERK1 antibody; P44MAPK antibody; PRKM 3 antibody; PRKM3 antibody; Protein Kinase Mitogen Activated 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P27361
Immunogen : Recombinant Human Mitogen-activated protein kinase 3 protein (11-379AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cell µLar context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation thro µgh the reg µLation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and reg µLation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the reg µLation of transcription upon stim µLation. However, other substrates are found in the cytosol as well as in other cell µLar organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the reg µLation of the endosomal dynamics, including lysosome processing and endosome cycling thro µgh the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis. The substrates include transcription factors (such as ATF2, BCL6, ELK1 ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1 MAP2, MAPT, PXN, SORBS3 or STMN1), reg µLators of apoptosis (such as BAD, BTG2, CASP9, DAPK1 IER3, MCL1 or PPARG), reg µLators of translation (such as EIF4EBP1) and a variety of other signaling-related molec µLes (like ARHGEF2, FRS2 or GRB10). Protein kinases (such as RAF1 RPS6KA1/RSK1 RPS6KA3/RSK2, RPS6KA2/RSK3, RPS6KA6/RSK4, SYK, MKNK1/MNK1 MKNK2/MNK2, RPS6KA5/MSK1 RPS6KA4/MSK2, MAPKAPK3 or MAPKAPK5) and phosphatases (such as DUSP1 DUSP4, DUSP6 or DUSP16) are other substrates which enable the propagation the MAPK/ERK signal to additional cytosolic and nuclear targets, thereby extending the specificity of the cascade.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK3
Research Areas : Neuroscience; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : CSAID Binding Protein 1 antibody; CSAID binding protein antibody; CSAID-binding protein antibody; Csaids binding protein antibody; CSBP 1 antibody; CSBP 2 antibody; CSBP antibody; CSBP1 antibody; CSBP2 antibody; CSPB1 antibody; Cytokine suppressive anti-inflammatory dr µg-binding protein antibody; EXIP antibody; MAP kinase 14 antibody; MAP kinase MXI2 antibody; MAP kinase p38 alpha antibody; MAPK 14 antibody; MAPK14 antibody; MAX interacting protein 2 antibody; MAX-interacting protein 2 antibody; Mitogen Activated Protein Kinase 14 antibody; Mitogen activated protein kinase p38 alpha antibody; Mitogen-activated protein kinase 14 antibody; Mitogen-activated protein kinase p38 alpha antibody; MK14_HUMAN antibody; Mxi 2 antibody; MXI2 antibody; p38 ALPHA antibody; p38 antibody; p38 MAP kinase antibody; p38 MAPK antibody; p38 mitogen activated protein kinase antibody; p38ALPHA antibody; p38alpha Exip antibody; PRKM14 antibody; PRKM15 antibody; RK antibody; SAPK2A antibody; Stress-activated protein kinase 2a antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16539
Immunogen : Recombinant Human Mitogen-activated protein kinase 14 protein (2-258AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cell µLar responses evoked by extracell µLar stim µLi such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated thro µgh phosphorylation and further phosphorylate additional targets. RPS6KA5/MSK1 and RPS6KA4/MSK2 can directly phosphorylate and activate transcription factors such as CREB1 ATF1 the NF-kappa-B isoform RELA/NFKB3, STAT1 and STAT3, but can also phosphorylate histone H3 and the nucleosomal protein HMGN1. RPS6KA5/MSK1 and RPS6KA4/MSK2 play important roles in the rapid induction of immediate-early genes in response to stress or mitogenic stim µLi, either by inducing chromatin remodeling or by recruiting the transcription machinery. On the other hand, two other kinase targets, MAPKAPK2/MK2 and MAPKAPK3/MK3, participate in the control of gene expression mostly at the post-transcriptional level, by phosphorylating ZFP36 (tristetraprolin) and ELAVL1 and by reg µLating EEF2K, which is important for the elongation of mRNA during translation. MKNK1/MNK1 and MKNK2/MNK2, two other kinases activated by p38 MAPKs, reg µLate protein synthesis by phosphorylating the initiation factor EIF4E2. MAPK14 interacts also with casein kinase II, leading to its activation thro µgh autophosphorylation and further phosphorylation of TP53/p53. In the cytoplasm, the p38 MAPK pathway is an important reg µLator of protein turnover. For example, CFLAR is an inhibitor of TNF-induced apoptosis whose proteasome-mediated degradation is reg µLated by p38 MAPK phosphorylation. In a similar way, MAPK14 phosphorylates the ubiquitin ligase SIAH2, reg µLating its activity towards EGLN3. MAPK14 may also inhibit the lysosomal degradation pathway of autophagy by interfering with the intracell µLar trafficking of the transmembrane protein ATG9. Another function of MAPK14 is to reg µLate the endocytosis of membrane receptors by different mechanisms that impinge on the small GTPase RAB5A. In addition, clathrin-mediated EGFR internalization induced by inflammatory cytokines and UV irradiation depends on MAPK14-mediated phosphorylation of EGFR itself as well as of RAB5A effectors. Ectodomain shedding of transmembrane proteins is reg µLated by p38 MAPKs as well. In response to inflammatory stim µLi, p38 MAPKs phosphorylate the membrane-associated metalloprotease ADAM17. Such phosphorylation is required for ADAM17-mediated ectodomain shedding of TGF-alpha family ligands, which res µLts in the activation of EGFR signaling and cell proliferation. Another p38 MAPK substrate is FGFR1. FGFR1 can be translocated from the extracell µLar space into the cytosol and nucleus of target cells, and reg µLates processes such as rRNA synthesis and cell growth. FGFR1 translocation requires p38 MAPK activation. In the nucleus, many transcription factors are phosphorylated and activated by p38 MAPKs in response to different stim µLi. Classical examples include ATF1 ATF2, ATF6, ELK1 PTPRH, DDIT3, TP53/p53 and MEF2C and MEF2A. The p38 MAPKs are emerging as important mod µLators of gene expression by reg µLating chromatin modifiers and remodelers. The promoters of several genes involved in the inflammatory response, such as IL6, IL8 and IL12B, display a p38 MAPK-dependent enrichment of histone H3 phosphorylation on \'Ser-10\' (H3S10ph) in LPS-stim µLated myeloid cells. This phosphorylation enhances the accessibility of the cryptic NF-kappa-B-binding sites marking promoters for increased NF-kappa-B recruitment. Phosphorylates CDC25B and CDC25C which is required for binding to 14-3-3 proteins and leads to initiation of a G2 delay after µLtraviolet radiation. Phosphorylates TIAR following DNA damage, releasing TIAR from GADD45A mRNA and preventing mRNA degradation. The p38 MAPKs may also have kinase-independent roles, which are tho µght to be due to the binding to targets in the absence of phosphorylation. Protein O-Glc-N-acylation catalyzed by the OGT is reg µLated by MAPK14, and, altho µgh OGT does not seem to be phosphorylated by MAPK14, their interaction increases upon MAPK14 activation induced by glucose deprivation. This interaction may reg µLate OGT activity by recruiting it to specific targets such as neurofilament H, stim µLating its O-Glc-N-acylation. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, thro µgh reg µLation of EPO gene expression. Isoform MXI2 activation is stim µLated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform EXIP may play a role in the early onset of apoptosis. Phosphorylates S100A9 at \'Thr-113\'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK14
Research Areas : Cancer; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : MAP kinase 13 antibody; MAP kinase p38 delta antibody; MAPK 13 antibody; MAPK-13 antibody; Mapk13 antibody; MGC99536 antibody; Mitogen activated protein kinase 13 antibody; Mitogen-activated protein kinase 13 antibody; Mitogen-activated protein kinase p38 delta antibody; MK13_HUMAN antibody; OTTHUMP00000016282 antibody; OTTHUMP00000016283 antibody; p38 delta antibody; P38delta antibody; PRKM13 antibody; SAPK 4 antibody; SAPK4 antibody; Stress activated protein kinase 4 antibody; Stress-activated protein kinase 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15264
Immunogen : Recombinant Human Mitogen-activated protein kinase 13 protein (1-365AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cell µLar responses evoked by extracell µLar stim µLi such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated thro µgh phosphorylation and further phosphorylate additional targets. Plays a role in the reg µLation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling thro µgh phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-reg µLation of the gene expression of CXCL14. Plays an important role in the reg µLation of epidermal keratinocyte differentiation, apoptosis and skin tumor development. Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway. MAPK13 also phosphorylates and down-reg µLates PRKD1 during reg µLation of ins µLin secretion in pancreatic beta cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK13
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracell µLar signal-reg µLated kinase 6 antibody; MAP kinase 12 antibody; MAP kinase p38 gamma antibody; MAPK 12 antibody; Mapk12 antibody; Mitogen Activated Protein Kinase 12 antibody; Mitogen activated protein kinase p38 gamma antibody; Mitogen-activated protein kinase 12 antibody; Mitogen-activated protein kinase p38 gamma antibody; MK12_HUMAN antibody; P38 GAMMA antibody; P38GAMMA antibody; PRKM12 antibody; SAPK 3 antibody; SAPK-3 antibody; SAPK3 antibody; Stress Activated Protein Kinase 3 antibody; Stress-activated protein kinase 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53778
Immunogen : Recombinant Human Mitogen-activated protein kinase 12 protein (314-367AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cell µLar responses evoked by extracell µLar stim µLi such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAPKAPK2, which are activated thro µgh phosphorylation and further phosphorylate additional targets. Plays a role in myoblast differentiation and also in the down-reg µLation of cyclin D1 in response to hypoxia in adrenal cells s µggesting MAPK12 may inhibit cell proliferation while promoting differentiation. Phosphorylates DLG1. Following osmotic shock, MAPK12 in the cell nucleus increases its association with nuclear DLG1 thereby causing dissociation of DLG1-SFPQ complexes. This function is independent of its catalytic activity and co µLd affect mRNA processing and/or gene transcription to aid cell adaptation to osmolarity changes in the environment. Reg µLates UV-induced checkpoint signaling and repair of UV-induced DNA damage and G2 arrest after gamma-radiation exposure. MAPK12 is involved in the reg µLation of SLC2A1 expression and basal glucose uptake in L6 myotubes; and negatively reg µLates SLC2A4 expression and contraction-mediated glucose uptake in ad µLt skeletal muscle. C-Jun (JUN) phosphorylation is stim µLated by MAPK14 and inhibited by MAPK12, leading to a distinct AP-1 reg µLation. MAPK12 is required for the normal kinetochore localization of PLK1 prevents chromosomal instability and supports mitotic cell viability. MAPK12-signaling is also positively reg µLating the expansion of transient amplifying myogenic precursor cells during muscle growth and regeneration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK12
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Human p38Beta MAP kinase mRNA complete cds antibody; MAP kinase 11 antibody; MAP kinase p38 beta antibody; MAPK 11 antibody; Mapk11 antibody; Mitogen activated protein kinase 11 antibody; Mitogen activated protein kinase p38 2 antibody; Mitogen activated protein kinase p38 beta antibody; Mitogen-activated protein kinase 11 antibody; Mitogen-activated protein kinase p38 beta antibody; MK11_HUMAN antibody; p38 2 antibody; p38-2 antibody; p38B antibody; p38Beta antibody; P38BETA2 antibody; PRKM11 antibody; Protein kinase mitogen activated 11 antibody; SAPK2 antibody; SAPK2B antibody; Stress activated protein kinase 2 antibody; Stress activated protein kinase 2b antibody; Stress-activated protein kinase 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15759
Immunogen : Recombinant Human Mitogen-activated protein kinase 11 protein (310-362AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK11 is one of the four p38 MAPKs which play an important role in the cascades of cell µLar responses evoked by extracell µLar stim µLi such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK11 functions are mostly redundant with those of MAPK14. Some of the targets are downstream kinases which are activated thro µgh phosphorylation and further phosphorylate additional targets. RPS6KA5/MSK1 and RPS6KA4/MSK2 can directly phosphorylate and activate transcription factors such as CREB1 ATF1 the NF-kappa-B isoform RELA/NFKB3, STAT1 and STAT3, but can also phosphorylate histone H3 and the nucleosomal protein HMGN1. RPS6KA5/MSK1 and RPS6KA4/MSK2 play important roles in the rapid induction of immediate-early genes in response to stress or mitogenic stim µLi, either by inducing chromatin remodeling or by recruiting the transcription machinery. On the other hand, two other kinase targets, MAPKAPK2/MK2 and MAPKAPK3/MK3, participate in the control of gene expression mostly at the post-transcriptional level, by phosphorylating ZFP36 (tristetraprolin) and ELAVL1 and by reg µLating EEF2K, which is important for the elongation of mRNA during translation. MKNK1/MNK1 and MKNK2/MNK2, two other kinases activated by p38 MAPKs, reg µLate protein synthesis by phosphorylating the initiation factor EIF4E2. In the cytoplasm, the p38 MAPK pathway is an important reg µLator of protein turnover. For example, CFLAR is an inhibitor of TNF-induced apoptosis whose proteasome-mediated degradation is reg µLated by p38 MAPK phosphorylation. Ectodomain shedding of transmembrane proteins is reg µLated by p38 MAPKs as well. In response to inflammatory stim µLi, p38 MAPKs phosphorylate the membrane-associated metalloprotease ADAM17. Such phosphorylation is required for ADAM17-mediated ectodomain shedding of TGF-alpha family ligands, which res µLts in the activation of EGFR signaling and cell proliferation. Additional examples of p38 MAPK substrates are the FGFR1. FGFR1 can be translocated from the extracell µLar space into the cytosol and nucleus of target cells, and reg µLates processes such as rRNA synthesis and cell growth. FGFR1 translocation requires p38 MAPK activation. In the nucleus, many transcription factors are phosphorylated and activated by p38 MAPKs in response to different stim µLi. Classical examples include ATF1 ATF2, ATF6, ELK1 PTPRH, DDIT3, TP53/p53 and MEF2C and MEF2A. The p38 MAPKs are emerging as important mod µLators of gene expression by reg µLating chromatin modifiers and remodelers. The promoters of several genes involved in the inflammatory response, such as IL6, IL8 and IL12B, display a p38 MAPK-dependent enrichment of histone H3 phosphorylation on \'Ser-10\' (H3S10ph) in LPS-stim µLated myeloid cells. This phosphorylation enhances the accessibility of the cryptic NF-kappa-B-binding sites marking promoters for increased NF-kappa-B recruitment.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK11
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : c Jun kinase 3 antibody; c-Jun N-terminal kinase 3 antibody; cJun N terminal kinase 3 antibody; FLJ12099 antibody; FLJ33785 antibody; JNK3 alpha protein kinase antibody; JNK3 antibody; JNK3A antibody; MAP kinase 10 antibody; MAP kinase antibody; MAP kinase p49 3F12 antibody; MAPK 10 antibody; Mapk10 antibody; MGC50974 antibody; mitogen activated protein kinase 10 antibody; Mitogen-activated protein kinase 10 antibody; MK10_HUMAN antibody; p493F12 antibody; p54bSAPK antibody; PRKM10 antibody; protein kinase mitogen activated 10 antibody; SAPK1b antibody; Stress activated protein kinase 1b antibody; stress activated protein kinase beta antibody; Stress activated protein kinase JNK3 antibody; Stress-activated protein kinase JNK3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53779
Immunogen : Recombinant Human Mitogen-activated protein kinase 10 protein (133-316AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracell µLar stim µLi such as proinflammatory cytokines or physical stress stim µLate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus reg µLates AP-1 transcriptional activity. Plays reg µLatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtub µLe reg µLator STMN2. Acts in the reg µLation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic reg µLation of the circadian clock (PubMed : 22441692).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK10
Research Areas : Neuroscience; Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ERK 2 antibody; ERK-2 antibody; ERT1 antibody; Extracell µLar Signal Reg µLated Kinase 2 antibody; Extracell µLar signal-reg µLated kinase 2 antibody; MAP kinase 1 antibody; MAP kinase 2 antibody; MAP kinase isoform p42 antibody; MAPK 1 antibody; MAPK 2 antibody; Mapk1 antibody; MAPK2 antibody; Mitogen-activated protein kinase 1 antibody; Mitogen-activated protein kinase 2 antibody; MK01_HUMAN antibody; P38 antibody; P40 antibody; P41 antibody; p42-MAPK antibody; P42MAPK antibody; PRKM1 antibody; PRKM2 antibody; protein kinase, mitogen-activated, 1 antibody; protein kinase, mitogen-activated, 2 antibody; protein tyrosine kinase ERK2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P28482
Immunogen : Recombinant Human Mitogen-activated protein kinase 1 protein (310-360AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cell µLar context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation thro µgh the reg µLation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and reg µLation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the reg µLation of transcription upon stim µLation. However, other substrates are found in the cytosol as well as in other cell µLar organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the reg µLation of the endosomal dynamics, including lysosome processing and endosome cycling thro µgh the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis. The substrates include transcription factors (such as ATF2, BCL6, ELK1 ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1 MAP2, MAPT, PXN, SORBS3 or STMN1), reg µLators of apoptosis (such as BAD, BTG2, CASP9, DAPK1 IER3, MCL1 or PPARG), reg µLators of translation (such as EIF4EBP1) and a variety of other signaling-related molec µLes (like ARHGEF2, DCC, FRS2 or GRB10). Protein kinases (such as RAF1 RPS6KA1/RSK1 RPS6KA3/RSK2, RPS6KA2/RSK3, RPS6KA6/RSK4, SYK, MKNK1/MNK1 MKNK2/MNK2, RPS6KA5/MSK1 RPS6KA4/MSK2, MAPKAPK3 or MAPKAPK5) and phosphatases (such as DUSP1 DUSP4, DUSP6 or DUSP16) are other substrates which enable the propagation the MAPK/ERK signal to additional cytosolic and nuclear targets, thereby extending the specificity of the cascade. Mediates phosphorylation of TPR in respons to EGF stim µLation. May play a role in the spindle assembly checkpoint. Phosphorylates PML and promotes its interaction with PIN1 leading to PML degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAPK1
Research Areas : Neuroscience; Signal transduction; Stem cells

Volume : 50 µL
Clone Number :
Aliases : FLH21957 antibody; FLJ10410 antibody; FLJ20373 antibody; FLJ90111 antibody; Hepatocyte progenitor kinase like/germinal center kinase like kinase antibody; HGK antibody; HPK/GCK like kinase antibody; HPK/GCK like kinase HGK antibody; HPK/GCK-like kinase HGK antibody; KIAA0687 antibody; M4K4_HUMAN antibody; MAP4K4 antibody; MAPK/ERK kinase kinase kinase 4 antibody; MEK kinase kinase 4 antibody; MEKKK 4 antibody; MEKKK4 antibody; Mitogen activated protein kinase kinase kinase kinase 4 antibody; Mitogen-activated protein kinase kinase kinase kinase 4 antibody; Nck interacting kinase antibody; Nck-interacting kinase antibody; NIK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95819
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 4 protein (866-1104AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP4K4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B lymphocyte serine/threonine protein kinase antibody; B lymphocyte serine/threonine-protein kinase antibody; BL44 antibody; GC kinase antibody; GCK antibody; Germinal center kinase antibody; germinal centre kinase (GC kinase) antibody; M4K2_HUMAN antibody; Map4k2 antibody; MAPK/ERK kinase kinase kinase 2 antibody; MEK kinase kinase 2 antibody; MEKKK 2 antibody; Mitogen activated protein kinase kinase kinase kinase 2 antibody; Mitogen-activated protein kinase kinase kinase kinase 2 antibody; Rab8 interacting protein antibody; Rab8 interacting protein, formerly antibody; Rab8-interacting protein antibody; RAB8IP antibody; RAB8IP, formerly antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q12851
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 2 protein (386-469AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway. Required for the efficient activation of JNKs by TRAF6-dependent stim µLi, including pathogen-associated molec µLar patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin. To a lesser degree, IL-1 and engagement of CD40 also stim µLate MAP4K2-mediated JNKs activation. The requirement for MAP4K2/GCK is most pronounced for LPS signaling, and extends to LPS stim µLation of c-Jun phosphorylation and induction of IL-8. Enhances MAP3K1 oligomerization, which may relieve N-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. Mediates also the SAP/JNK signaling pathway and the p38 MAPKs signaling pathway thro µgh activation of the MAP3Ks MAP3K10/MLK2 and MAP3K11/MLK3. May play a role in the reg µLation of vesicle targeting or fusion. reg µLation of vesicle targeting or fusion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP4K2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DKFZp779A1753 antibody; MAP-4 antibody; MAP4 antibody; MAP4_HUMAN antibody; MGC8617 antibody; Microtub µLe associated protein 4 antibody; Microtub µLe-associated protein 4 antibody; OTTHUMP00000210723 antibody; OTTHUMP00000210725 antibody; OTTHUMP00000210727 antibody; OTTHUMP00000210730 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P27816
Immunogen : Recombinant Human Microtub µLe-associated protein 4 protein (575-818AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-neuronal microtub µLe-associated protein. Promotes microtub µLe assembly.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP4
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : M3K9_HUMAN antibody; Map3k9 antibody; MEKK9 antibody; Mitogen activated protein kinase kinase kinase 9 antibody; Mitogen-activated protein kinase kinase kinase 9 antibody; Mixed lineage kinase 1 (tyr and ser/thr specificity) antibody; Mixed lineage kinase 1 antibody; MLK1 antibody; PRKE1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P80192
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 9 protein (864-1098AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cell µLar responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade thro µgh the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway reg µLates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K9
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AURA2 antibody; c COT antibody; Cancer Osaka thyroid oncogene antibody; CCOT antibody; COT antibody; COT proto oncogene serine/threonine protein kinase antibody; EST antibody; ESTF antibody; Ewing sarcoma transformant antibody; FLJ10486 antibody; M3K8_HUMAN antibody; MAP3K 8 antibody; MAP3K8 antibody; MEKK8 antibody; Mitogen activated protein kinase kinase kinase 8 antibody; Mitogen-activated protein kinase kinase kinase 8 antibody; Proto oncogene cCot antibody; Proto-oncogene c-Cot antibody; Serine/threonine protein kinase cot antibody; Serine/threonine-protein kinase cot antibody; TPL 2 antibody; TPL-2 antibody; TPL2 antibody; Tumor progression locus 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P41279
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 8 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the reg µLation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection thro µgh negative reg µLation of type I interferon (IFN) production. In vitro, activates MAPK/ERK pathway in response to IL1 in an IRAK1-independent manner, leading to up-reg µLation of IL8 and CCL4. Transduces CD40 and TNFRSF1A signals that activate ERK in B-cells and macrophages, and thus may play a role in the reg µLation of immunoglob µLin production. May also play a role in the transduction of TNF signals that activate JNK and NF-kappa-B in some cell types. In adipocytes, activates MAPK/ERK pathway in an IKBKB-dependent manner in response to IL1B and TNF, but not ins µLin, leading to induction of lipolysis. Plays a role in the cell cycle. Isoform 1 shows some transforming activity, altho µgh it is much weaker than that of the activated oncogenic variant.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K8
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : MAP3K7CL antibody; C21orf7 antibody; TAK1LMAP3K7 C-terminal-like protein antibody; TAK1-like protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P57077
Immunogen : Recombinant Human MAP3K7 C-terminal-like protein (1-142AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K7CL
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : M3K7_HUMAN antibody; MAP3K 7 antibody; Map3k7 antibody; MEKK7 antibody; Mitogen activated protein kinase kinase kinase 7 antibody; Mitogen-activated protein kinase kinase kinase 7 antibody; TAK1 antibody; TGF beta activated kinase 1 antibody; TGF-beta-activated kinase 1 antibody; TGF1a antibody; Transforming growth factor beta activated kinase 1 antibody; Transforming growth factor-beta-activated kinase 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43318
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 7 protein (101-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cell µLar responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade thro µgh the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1 MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1 but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K7
Research Areas : Cancer; Cardiovasc µLar; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Apoptosis signal reg µLating kinase 2 antibody; Apoptosis signal-reg µLating kinase 2 antibody; ASK2 antibody; EC 2.7.11.25 antibody; M3K6_HUMAN antibody; MAP3K6 antibody; MAPKKK6 antibody; MEKK6 antibody; MGC125653 antibody; MGC20114 antibody; Mitogen-activated protein kinase kinase kinase 6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95382
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 6 protein (905-990AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K6
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Apoptosis signal reg µLating kinase 1 antibody; Apoptosis signal-reg µLating kinase 1 antibody; ASK 1 antibody; ASK-1 antibody; ASK1 antibody; M3K5 antibody; M3K5_HUMAN antibody; MAP/ERK kinase kinase 5 antibody; MAP3K5 antibody; MAPK/ERK kinase kinase 5 antibody; MAPKKK5 antibody; MEK kinase 5 antibody; MEKK 5 antibody; MEKK5 antibody; Mitogen activated protein kinase kinase kinase 5 antibody; Mitogen-activated protein kinase kinase kinase 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99683
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 5 protein (363-431AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cell µLar responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway thro µgh mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS). Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade thro µgh the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1 MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs). Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K5
Research Areas : Cardiovasc µLar; Cell biology

Volume : 50 µg
Clone Number :
Aliases : dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody; FLJ42439 antibody; KIAA0213 antibody; M3K4_HUMAN antibody; MAP three kinase 1 antibody; MAP/ERK kinase kinase 4 antibody; MAP3K4 antibody; MAPK/ERK kinase kinase 4 antibody; MAPKKK4 antibody; MEK kinase 4 antibody; MEKK 4 antibody; MEKK4 antibody; Mitogen-activated protein kinase kinase kinase 4 antibody; MTK1 antibody; predicted protein of HQ0412 antibody; PRO0412 antibody; RP3-473J16.4 antibody; SSK2/SSK22 MAP kinase kinase kinase; yeast; homolog of antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y6R4
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 4 protein (53-145AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K4
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dJ862P8.3 antibody; KIAA1804 antibody; M3KL4_HUMAN antibody; Mitogen activated protein kinase kinase kinase antibody; Mitogen-activated protein kinase kinase kinase MLK4 antibody; Mixed lineage kinase 4 antibody; MLK 4 antibody; Mlk4 antibody; RP5 862P8.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5TCX8
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 21 protein (640-794AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Negative reg µLator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K21
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : M3K2_HUMAN antibody; Map3k2 antibody; MAPK/ERK kinase kinase 2 antibody; MEK kinase 2 antibody; MEKK 2 antibody; MEKK2b antibody; Mitogen activated protein kinase kinase kinase 2 antibody; Mitogen-activated protein kinase kinase kinase 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2U5
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 2 protein (357-619AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of a protein kinase signal transduction cascade. Reg µLates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : MAP3K19 antibody; RCK antibody; YSK4Mitogen-activated protein kinase kinase kinase 19 antibody; EC 2.7.11.1 antibody; Reg µLated in COPD antibody; protein kinase antibody; SPS1/STE20-related protein kinase YSK4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q56UN5
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 19 protein (45-168AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K19
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : EC 2.7.11.25 antibody; Leucine zipper bearing kinase antibody; Leucine zipper-bearing kinase antibody; LZK antibody; M3K13_HUMAN antibody; MAP3K13 antibody; MEKK13 antibody; MGC133196 antibody; Mitogen activated protein kinase kinase kinase 13 antibody; Mitogen-activated protein kinase kinase kinase 13 antibody; Mixed lineage kinase antibody; MLK antibody; OTTHUMP00000210397 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43283
Immunogen : Recombinant Human Mitogen-activated protein kinase kinase kinase 13 protein (506-835AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Activates the JUN N-terminal pathway thro µgh activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to reg µLate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MAP3K13
Research Areas : Signal transduction