Dab1 (Phospho Tyr220) rabbit pAb - 50 μL

Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins. function: Adapter molecule functioning in neural development. May regulate SIAH1 activity. PTM: Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. similarity: Contains 1 PID domain. subunit: Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.