Acute myocardial infarction (AMI) seriously threatens human life. In this study we aimed to systemically analyze the function of key gene modules in human platelets in AMI. We used weighted
The impact of chromosomal fusions on 3D genome folding and recombination in the germ lineThe impact of chromosomal fusions on 3D genome folding and recombination in the germ line
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The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of
The impact of cross-kingdom molecular forensics on genetic privacyThe impact of cross-kingdom molecular forensics on genetic privacy
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Recent advances in metagenomic technology and computational prediction may inadvertently weaken an individual’s reasonable expectation of privacy. Through cross-kingdom genetic and metagenomic forensics, we can already predict at least a
Expression of Escherichia coli araE and modified lacY genes in Campylobacter jejuni is not sufficient for arabinose transportExpression of Escherichia coli araE and modified lacY genes in Campylobacter jejuni is not sufficient for arabinose transport
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Introduction: Unlike Escherichia coli , Campylobacter jejuni is unable to import a range of sugars, including arabinose, which makes common expression vectors, such as pBAD33, non-functional in these bacteria. Aim: The aim of this study was
Gene Flow and Individual Relatedness Suggest Population Spatial Connectivity of Sinogastromyzon sichangensis (Cypriniformes: Balitoridae) in the Chishui River, ChinaGene Flow and Individual Relatedness Suggest Population Spatial Connectivity of Sinogastromyzon sichangensis (Cypriniformes: Balitoridae) in the Chishui River, China
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Sinogastromyzon sichangensisis a hillstream loach endemic to the upper Yangtze River, China. It is unclear whether this fish lives in a very restricted area or may be dispersed over
Genetic variations in autoimmune genes and VKH diseaseGenetic variations in autoimmune genes and VKH disease
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Purpose: Vogt-Koyanagi-Harada (VKH) disease is a rare autoimmune disease. The autoimmune response in VKH disease is against the melanin-producing cells; therefore, in affected individuals melanocyte-containing organs manifest disease symptoms including eyes,
The development and controversy of competitive endogenous RNA hypothesis in non-coding genesThe development and controversy of competitive endogenous RNA hypothesis in non-coding genes
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As a momentous post-transcriptional regulator, microRNAs (miRNAs) are attracting more and more attention. The classical miRNAs regulated mechanism shows it binds to the targets’ 3’UTR thus play the role in
ePath: an online database towards comprehensive essential gene annotation for prokaryotes.ePath: an online database towards comprehensive essential gene annotation for prokaryotes.
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Experimental techniques for identifying essential genes (for example) in prokaryotes are generally expensive, taking a long time and sometimes unrealistic. Emerging silico methods provide alternative methods for for example prediction,
A Simple Method for Sample Preparation to Facilitate Efficient Whole-Genome Sequencing of African Swine Fever Virus.A Simple Method for Sample Preparation to Facilitate Efficient Whole-Genome Sequencing of African Swine Fever Virus.
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In recent years, African swine fever has become the main threat of animal health for the pig industry. To facilitate the rapid genetic analysis of its causal agent, the African
Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics.Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics.
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Despite hundreds of sequentered arabidopsis genomes, very few things are known about the degree of genomic collinearity within a single species due to the low number of assemblies at the