PinX1 rabbit pAb - 50 μL

Domain: The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity. function: Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. similarity: Belongs to the PINX1 family. similarity: Contains 1 G-patch domain. subcellular location: In nucleoli and at telomere speckles. subunit: Binds to MCRS1, TERT and TERF1. tissue specificity: Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.