IL-1F7 rabbit pAb - 50 μL

The protein encoded by this gene is a member of the interleukin 1 Cytokine family. This Cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This Cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a Cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],