IF5A1 rabbit pAb - 50 μL

Function: The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond. PTM: eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine). similarity: Belongs to the eIF-5A family. subunit: Found in a complex with Ran and XPO4. The hypusine modification increases the interaction with XPO4. tissue specificity: Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level).