EEA1 rabbit pAb - 100 μL

Disease: Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. Domain: The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. similarity: Contains 1 C2H2-type zinc finger. similarity: Contains 1 FYVE-type zinc finger. subunit: Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.