CASS4 rabbit pAb - 50 μL

Alternative products: Experimental confirmation may be lacking for some isoforms, function: Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading. PTM: Phosphorylated on tyrosines by SRC. similarity: Belongs to the CAS family. similarity: Contains 1 SH3 domain. subunit: Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus). tissue specificity: Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.